In Uzbekistan, the sphere of ART is relatively new and the problems of pregnancy after ART procedures remain both a socio-psychological and economic problem. The article discusses the effect of melatonin use on the probability of pregnancy as the first clinical trials in this country. A comparative analysis of the results between groups of women who used melatonin and a control group is made. The physiologic mechanisms of melatonin action, its effect on reproductive health and the prospects for its use in clinical practice are highlighted. Clinical trials using melatonin in the field of assisted reproductive technologies (ART) are conducted for the first time in Uzbekistan. This is an innovative approach aimed at studying the effectiveness and safety of this drug in improving reproductive indicators in patients.
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