All articles - Infectious Diseases
Number of articles: 758
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Evaluation of the effectiveness of complex treatment of herpetik keratoconjunctivitis with the use of ozone through orion-si glassesWe examined 26 patients (26 eyes) with herpetic keratitis in age from 17 to 63 years. Men were - 15, women - 11. A study group comprised 14 patients (14 eyes) who used traditional conservative therapy with the use of ozone therapy and the control group consisted of 12 patients (12 eyes) who used only the traditional medical therapy. As a result of comparative clinical studies and the comprehensive application of the method of ozone therapy and traditional medical treatment of herpetic keratitis showed that combined application allows you to increase the effectiveness of treatment, improves clinical outcomes.
Journal problems of biology and medicine -
Quality of children and adolescents life with pulmonary tuberculosis depend- Ing on existence of the accompanying pathologyWork is devoted to studying of life quality parameters of children and adolescents with tuberculosis. Laboratory and instrumental methods examination of patients do not cover all aspect of tuberculous infection and do not allow valuing the condition of children and adolescents with pulmonary tuberculosis. At analysis of life’s quality there is full possibility to define the influence of the disease on physical, psychological and social aspects of the organism’s functioning. The analysis of quantitative indexes children and adolescents quality of life was conducted depending on accompanying pathology. For research was used the questionnaire of Pediatric Quality of Life Inventory - PedsQL. Questionnaire of PedsQL 4.0. includes 23 questions, incorporated in 4 scales. Every question has 5 variants of answers: "no", "hardly ever", "sometimes", "often" and "almost always", from which it is needed to choose one, most going near a situation.
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Our investigations were performed with purpose to study 30 infectious and somatic diseases complicated by otoantritis. It was found that among young children at the age under 14 boys were 4 (33,3%), and girls were 8 (66,7%), in 24 (40%) there was spontaneous perforation of tympanum. In 5 (41.6%) patients the diagnostic tym-panopuncture was performed and in 12 of patients antrotomy was made. Of 12 patients with otoantritis in 2 (16.7%) patients complications were developed, such as otogenic sepsis and in 3 (24.1%) patients otogenic meningitis; in 3 (24.1%) patients - paresis of facial nerve; and lethal outcome in one (1,6%) patient. Thus, it is necessary to perform tympanopuncture, paracentesis, antrotomy in combination with antibacterial, for diagnosis and treatment otoantritis in infants. -
Among all the factors of the so-called physiological immunosuppression that contribute to the spread and reactivation of cytomegalovirus infection, the first place belongs to pregnancy. Cytomegalovirus infection (CMVI) - a disease caused by a DNA-containing virus from the herpesvirus family, refers to infections, the clinical manifestation of which becomes possible in conditions of primary or secondary immunodeficiency. At immunocompetent persons in most cases proceeds without clinical symptoms. It is this circumstance that determines the special interest in the problem of CMVI during pregnancy [1, 2, 3]. -
Острый средний отит (ОСО) у ВИЧ-инфицированных детей относится к неотложной ЛОР- патологии и является проблемой не только для оториноларингологов, но и педиатров, детских инфекционистов. На основании ретроспективного анализа автором отмечается рост заболеваемости ОСО, учащение негнойных форм отита. Клинико-лабораторные данные обследования 35 ВИЧ-инфицированных больных детей с использованием ПЦР- тестирования и бактериологического исследования позволили автору судить об активности стрептококков, микоплазм, вирусов, хламидий и др. возбудителей в этиологии ОСО. Предложено комплексное лечение больных ОСО в оториноларингологическом, инфекционном отделении под наблюдением оториноларинголога с учетом этиопатогенеза заболевания.
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Estimation of efficiency of application of minimally invasive technologies in diagnostics and treatment of tuberculosis obstructive forms of the urinary waysPercutaneous nephrostomy and stenting for tuberculosis of the kidneys with supravesical obstruction creates the conditions for normalizing the passage of urine. The accumulated experience allows us to positively assess the role of PKNS as a method of choice for the release and assessment of the reserves of renal function against the background of tuberculous changes in the upper urinary tract, and stenting for tuberculosis of the kidneys with supravesical obstruction creates the conditions for normalizing the passage of urine.
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Purpose of work. In the fluid of echinococci parasitizing in humans, the following species of microorganisms were found: Staphylococus aureus, Staphylococus albus, Proteus vulgaris, Bacillis sereus, Escherichia coli, Escherichia freundii, Aerobacterae rogenes, Paracolobactrum coliformi, Enterococus faecium, Ent.liguefaciesvar. Zymogen, Corynobacterium pyogenes, Streptococus uberis, Bruceii amelitensis, Mycobacterium tuberculosis. Materials and methods of research. Of the 187 samples studied, 112 of them were examined in patients and assigned to the 1st age group, 15-to the 2nd and 32-to the 3rd age group, containing different microflora. The remaining 25 cchinococcal bladders were bactcriologically sterile. Research result. Of the 187 samples examined, the contents of cchinococcal cysts were infected in 112 cases. Of these, 52 bubbles were localized in the lungs; 22 bubbles localized in the lungs had aerobic bacteria, since the bacteria penetrated by airborne droplets, with weak immunity. With a single lesion of the liver alone, we identified 44 cases of infected echinococcal bladder. Bacterial infection depends on the modification of echinococcal bladders. Summary. In echinococcal cysts are also detected pathogenic protozoa, dangerous to the health of patients. Any Echinococcus in the patient's body is a potential focus of purulent infection. -
Clinical diagnostic features of cns infectious defects in hiv-infected patientsAmong the observed patients, the predominant route of HIV infection was injection. The Epstein – Barr virus, Toxoplasma and Mycobacterium tuberculosis were the most frequent pathogens affecting the CNS in HIV-positive patients. The disease developed mainly in young people, regardless of gender. Infectious lesions of the CNS in HIV-positive patients develop gradually and manifest themselves clinically against the back-ground of deep immunodeficiency
Journal problems of biology and medicine -
Complex research in the diagnostics of chronic viral hepatitis in childrenThe object of the study were 120 children from 3 to 18 years old, patients with chronic viral hepatitis. General clinical, biochemical, specific laboratory, instrumental, radiation: complex echographic studies, MSCT, MRI, SI of the liver, spleen, biliary tract were used, histological criteria of liver damage, as well as sta-tistical research methods were studied. The use of a set of methods of instrumental methods, along with clinical laboratory and, according to indications, histological studies in chronic viral hepatitis in children, makes it possible to formulate a definitive and reliable diagnosis in the early stages of the disease and carry out ade-quate therapy, prevent complications and transition to a more severe degree of activity or cirrhosis the liver
Journal problems of biology and medicine -
The incidence of cutaneous leishmaniasis in Uzbekistan in recent years has no tendency to decline. In Uzbekistan for the first time in recent years, in the Scientific Research Institute of Medical Parasitology named after L.M. Isaev using molecular-biological diagnostic methods (PCR) was diagnosed species affiliation of the causative agents of cutaneous leishmaniasis. The results of the conducted studies revealed prevalence of the pathogen agent and vectors of the anthroponotic form of cutaneous leishmaniasis in traditionally considered regions. -
Rationale for treatment of patients with echinococcosis, taking into account the functional state of the hepatobiliary systemThe main biochemical indicts of hepatic functions the aktivifres of alanine aminotransferase aspartate aminotransferase. Concentration of bilirubin, were studied in the sera of 72 patients with liver echinococcosis. There were detected the cytolycitic syndrome in 15, 25%, mesenchymal – inflammatory syndrome in 41,2% and cholestasis in 25,3% cases of disease. Test results medicated that ursodeoxycholic acid had hepatoprotective effect. It shoold be used in combine usage with albendazole to correct the liver function, which disturbed by action of Echinococcosis ghanulosis and albendazole
Journal problems of biology and medicine -
The prevalence of neurocirculatory dystonia in hiv-infected population as a function of the marital status, an accessory to the ethnical and religious groupAn analysis of the prevalence of NDCs in the HIV infected population of Fergana has been performed, depending on the age, marital status, as well as belonging to the ethnic and religious group. It is a comprehensive assessment of the unique nature of the course of the disease in patients of different sex and age, as well as with different marital status, enabling the doctor to improve early diagnosis and prevention, for further planning an individual approach to treatment.
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Epidemiological model and algorithms of prevention Of neurocyryculatory dystony in hiv-infected population under the conditions of the fergana valley of uzbekistanIn the course of the epidemiological research, were identified 18 major risk factors in the formation of NCDs among the HIV-infected population. Based on the data obtained, was developed an algorithm for the early detection and prevention of NCD in an HIV-infected population of the Fergana Valley of Uzbekistan.
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Epidemiological-clinical peculiarities of comorbid pathology in hiv infected patients with neurocirculatory dystoniaThe research, which we conducted, is based on an epidemiological analysis of the results of a questionnaire of 341 HIV-infected persons with NCDs. This study was conducted using specially developed questionnaires, as well as instrumental diagnostic methods. The results of the research showed that the clinical diagnosis of NCDs in HIV-infected patients with comorbid pathology is a big challenge. In turn, this indicates the importance of carrying out complex instrumental and special diagnostic methods for patients in this group.
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Spectral analysis of the cardianium in pregnant infectious risk groupsIn the article features of vegetative regulation of hemodynamics in pregnant women with infectious risk on the basis of heart rate variability (HRV) are considered. The state and correlation of parameters of sympathetic, parasympathetic and humoral regulation are described. Spectral analysis of cardiac rhythm can be recommended as a method for screening the state of metabolic supply, neurovegetative regulation of hemodynam-ics, the possibilities of compensatory-adaptive mechanisms and the level of anti-stress resistance of the organism of a pregnant woman
Journal problems of biology and medicine -
Role and place of ecgography methods in diagnosis of chronic viral hepatitis in childrenThis study is based on the results of a comprehensive clinical, laboratory and instrumental examination of 270 children aged 3 to 18 years with chronic viral hepatitis. Clinical manifestations of CVH were represent-ed by the following syndromes: asthenovegetative, dyspeptic, cytolytic, hemorrhagic, cholestatic. The frequency and severity of all clinical syndromes increased as the activity of CVH increased, but did not depend on the etiology of the disease. In this regard, the analysis of the results of clinical and biochemical studies is given by the degree of activity of the pathological process in the liver. Each of the studied methods of ultrasound has a definite role and place in the refined diagnosis of chronic hereditary hypertension in children. The highly in-formative technologies of echographic diagnostics studied by us are recommended for wider implementation in various parts of health care. For this purpose, a program for the phased use of a set of ultrasound hepatology technologies in pediatric practice is proposed.
Journal problems of biology and medicine -
In babies with sepsis, there is a change in the quantitative and qualitative composition of the microbiota, manifested by an increase in the feces of oil and propionic acids, which indicates the activation of opportunistic flora and severe anaerobes. The displacement of the aerobic index in the region of sharply negative values and a sharp increase in the ratio of the level of iso-acids and the ratio of isovaleric acid to valeric acid, indicates an increase in the activity of aerobic microflora with proteolytic activity in the lumen of the intestine in patients with sepsis. The increase in agglomeration properties of leukocytes is associated with an increase in the content of butyric acid in the blood of patients with sepsis. -
Clinical laboratory course of hepatitis “a ”in children with lyambliaThis article presents data on 47 patients from 3 to 14 years, infected hepatitis A and hepatitis A in con-junction with giardiasis intestines. From 47 patients were identified in 23 (48,9%) for the hepatitis A in con-junction with intestinal giardiasis. Giardiasis intestines in conjunction with hepatitis A is more common in boys aged 11 to 14 years. hepatitis A in conjunction with intestinal giardiasis has its own characteristics: longer during the incubation and prodromal period; in icteric period often revealed intoxication and dyspeptic syn-dromes; long bounces back blood biochemical parameters in the recovery period; passion for the frequency of relapses in a period of convalescence
Journal problems of biology and medicine -
The relevance of the problem is determined by the high level of chickenpox, the omnipresence of the pathogen, increasing the proportion in the total infectious diseases, significant economic damage, inefficiency of implemented in practice prevention measures (isolation of patients, quarantine). During chickenpox the rash in adults are often massive, accompanied by fever, general toxic phenomena, severe itching. Despite the low level of chickenpox in adults, the risk of severe complications and even deaths is higher than in children -
The peculiarities of neurologic symptomatics in the serious memeting of the enterherous etiology41 patients with serous enteroviral meningitis were examined, the results of the analysis of clinical and neurological manifestations of enteroviral meningitis showed that it was more often characterized by an acute onset with pronounced neurologic symptoms and a good curative effect from spinal puncture as well as cases of pleocytosis of neutrophil and mixed character.
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Comparative characteristics and diagnostic value of the taxonomic characteristics of pathogens of infectious inflammatory diseases of humansThe aim was a comparative study of the variability of some taxonomic characters sown E.coli from sick women urinary tract infections. It was found that E.coli strains isolated from different habitats of the body healthy and sick women with varying frequency detected taxonomic characteristics, which are associated with the adhesiveness of the pathogen. The strains exhibit variability mainly by fermentation of mannitol, sucrose, arabinose, glucose, sodium citrate, hemolytic activity.
Journal problems of biology and medicine -
State of blood flow data of ultrasound angiography in tuberculosis of kidneysUltrasonic angiography in nephrotuberculosis is a highly informative method in assessing renal blood flow. The use of ultrasonic angiography in the destructive forms of tuberculosis of the kidneys allows us to specify the tactics of management and treatment of patients
Journal problems of biology and medicine -
Informativity of magnetic-resonance tomography in diagnosis of tuberculosis spondilites and its complications89 magnetic resonance tomograms, which were performed by 72 patients with TS, were analyzed. A spe-cific process was localized in the cervical spine in two patients, in the thoracic and thoracolumbar - in 38, in the lumbar and lumbosacral in 32 patients. Isolated lesions of one or two vertebrae were observed in four cas-es, contact destruction in 48, a combination of contact and isolated destruction at 15. Combination of MRI and X-ray methods broadens the notion of morphological changes in the spine, the stage of the tuberculous process, allows one to study the patterns of development And the dynamics of TC, the effectiveness of conservative and operative treatment
Journal problems of biology and medicine -
Peculiarities of the acute of acute surgical pathology in hiv infected / aids patientsWith acute diseases of the abdominal cavity, 10 patients were hospitalized, 4 of them for acute appendi-citis, 3 for perforated ulcers, 1 for acute cholecystitis, 1 for gastrointestinal bleeding and 1 for infiltrates and phlegmon retroperitoneal space. Studies were conducted to analyze the immune status of patients taking into account the phagocytic activity of neutrophils, humoral and cellular immunity. HIV infection is not an excuse for refusing surgery in patients with acute surgical pathology. Observations showed that the HIV-associated infection burdens the course of the postoperative period. In patients, there is a prolonged phenomenon of intox-ication, pain, prolonged course of suppuration of the wound, as well as a difficult cleansing of the wound
Journal problems of biology and medicine -
Clinical features chronic hepatitis b in patients with hiv infectionImmunodeficiency arisen because HIV accelerates HBV. In limited to users with mixed infections of HIV and HBV, there is a clear inflammation liver tissue and fibrosis processes clinical features chronically hepatitis have been studied in patients with HIV infection. In diseases like hepatitis B chronically co infection HIV pa-tients with overt clinical signs of hepatitis B is not observed, the disease is on the background of associated diseases and symptoms of drug abuse. HIV exacerbates HBV infection. Infection with HBV and HIV affects in the main reproductive and working-age segment of the population. As a consequence carries problems not only social, but also economic.
Journal problems of biology and medicine
