CURRENT APPROACHES AND NEW RESEARCH IN
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RESTORATION OF FERTILITY AFTER SURGERY TO REMOVE
UTERINE FIBROIDS IN PATIENTS OF THE OLDER REPRODUCTIVE
GROUP.
Razzakova Nilufar Saydaxmatovna
Qosimova Hadicha Jahongir qizi
Tashkent Medical Academy, Tashkent, Uzbekistan
https://doi.org/10.5281/zenodo.14986996
Keywords:
uterine fibroids, myomectomy, late reproductive age, ovarian
reserve, fertility.
Razzakova N.S.
1
, Qosimova H. J.
1
Relevance.
Myomectomy is a method of choice in women of reproductive
age. Despite significant research, this literature data is contradictory regarding
the indications and contraindications for this operation, as well as the operative
approach and technique of the operation [2, 8, 7]. At the same time, the
effectiveness of infertility treatment largely depends on the condition of the
ovarian reserve in each specific case. In the last decade, the concept of "ovarian
reserve" and its significance in choosing infertility treatment methods have been
widely discussed [3, 6, 15].
It is one of the most common diseases in women,
reaching 12-25% of all gynecological diseases. The highest incidence of uterine
fibroids occurs during the late reproductive period and before menopause.
There is an opinion that the true prevalence of myoma is significantly higher and
exceeds 70% both in Russia and abroad.
Purpose
.
Study of the significance of the myomectomy method for the
implementation of reproductive function in the presence of single myomatous
nodes that do not damage the uterine cavity.
Research material and methods.
In order to analyze the effectiveness of
myomectomy in relation to the restoration of fertility in older women of
reproductive age, for whom infertility was the main indication for surgical
intervention, a clinical and statistical analysis of the long-term results of the
operation was conducted.
Discussion of results.
By analyzing the frequency of pregnancy in patients
with uterine fibroids (UF) of older reproductive age with reduced and low
ovarian reserve (OR), the following conclusions can be drawn.
With reduced ovarian reserve, pregnancy occurred in 3 out of 7 patients
(14.2%). In patients with low ovarian reserve, independent pregnancy after
ovulation stimulation was not recorded. The use of assisted reproductive
technologies (ART) - extracorporeal fertilization (ECO) allowed achieving
pregnancy in 1 out of 11 patients (5.2%).
CURRENT APPROACHES AND NEW RESEARCH IN
MODERN SCIENCES
International scientific-online conference
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Thus, when establishing an initially reduced ovarian reserve, the patient
should be informed of a more pronounced disruption of the morphofunctional
state of the ovaries after myomectomy and, as a consequence, possible failure in
the implementation of reproductive function. With initially low ovarian reserve
after myomectomy, reproductive function can only be achieved through IVF. If
there is no need to perform it, if the patient wishes, it is advisable to perform
myomectomy only for organ-preserving purposes.
Literature:
1.
Nargund G. et al. The impact of ovarian cystectomy on ovarian response
during IVF cycles// Hum. Repr.- 1996. - Vol. 11 - p. 81 - 83.
2.
Nezhat F.R., Roemisch M., Nezhat G.H. et al. Recurrence rate after
myomectomy. // J. Am. Assoc. Gynecol. Laparosc. - 1998. - № 15. -p. 237-240.
3.
Pritts E.A. Fibroids and infertility: a sistematic review of the evidens //
Obstet. Gynecol. Surv. – 2001. – V.56. - №8. – P.483-492.
