CURRENT APPROACHES AND NEW RESEARCH IN
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International scientific-online conference
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THE EFFECTIVENESS OF PRP THERAPY FOR THE TREATMENT OF
VITILIGO
Zh.M.Umarov
F.Kh.Abboskhanova.
B.R.Parpiev
Tashkent medical academy
Department of dermatovenerology and cosmetology
https://doi.org/10.5281/zenodo.15195022
Relevance.
Vitiligo is the most common type of hair loss and affects up to
80% of men and 40% of women. In pathogenesis, the main role is assigned to
the androgen-converting enzyme 5a-reductase, which catalyzes the conversion
of testosterone into the more active form 5a-dehydrotetosterone. The decrease
in length and diameter, as well as the decrease in density, is the result of a
combination of changes in the hair growth cycle and the miniaturization of
follicles into flesh to complete hair loss in androgen-dependent areas of the
scalp. In addition, baldness affects the psycho-emotional state of a person, which
significantly reduces the quality of life. the purpose of the study. To study the
effectiveness of PRP therapy in the treatment of vitiligo.
Material and methods.
32 male patients with vitiligo were monitored,
including 1,53 Dermatovenerology and Aesthetic Medicine No. 3/2023 and stage
2 of the disease, aged 18 to 32 years. The duration of the disease ranged from
several months to 5 years. 27 (84.37%) patients had changes in dynamics for the
better. The results of the study. In our study, all patients were prescribed and
treated with a PRP therapy course of 1 procedure with an interval of 7 days for
two months, followed by 1 procedure with an interval of 14 days for one month.
The results
of the study were evaluated using a dermatoscope before and
after three months of PRP therapy in patients withvvitiligo , during which
positive results were obtained from plasma injections on skin and their
morphometric parameters in adult vitiligo. Table 1. Dynamics of morphometric
parameters of hair growth before and after the course of PRP therapy.
Skin growth parameters hair density per cm2 proportion, (%) average
diameter of all hair/ terminal hair, microns before treatment 170 21 after
treatment. Dynamics before treatment 203 0 11 58/68 62/68- 47, 6 % +4/0 ( +
6, 9 %/0 %) after treatment +71 ( +15, 4 %)- 5 0 % +12/+10 ( +20,1 %/15,3 %)
proportion of telogen hair, % 31 15- 51.6% + 66 %
Conclusions:
clinical studies have shown that PRP therapy has a positive
effect on hair growth and their morphometric parameters in vitiligo.
CURRENT APPROACHES AND NEW RESEARCH IN
MODERN SCIENCES
International scientific-online conference
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