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THE EFFECTIVENESS OF TOOTHPASTE WITH CARLOVY VARY SALT FOR TREATING
PATIENTS WITH INFLAMMATORY PERIODONTAL DISEASES
Xaydarov Ulug’bek
Samarkand State Medical University, Uzbekistan
Axmedov Alisher Astanovich
Samarkand State Medical University, Uzbekistan
AB O U T ART I CL E
Key words:
Toothbrush, gingivitis, periodontitis,
clinical study, cytomorphological examination.
Received:
20.06.2024
Accepted
: 25.06.2024
Published
: 30.06.2024
Abstract:
The effectiveness of a toothpaste
containing carbazbad salt was studied in patients
with inflammatory periodontitis, a group of 20
people. Ten of them suffered from chronic
catarrhal gingivitis.During dental examination,
the indicators of CPU, PMA, Green-Vermillion and
interdental papillary bleeding PBI were measured
before, 7, 14 and 30 days after the first application
of the paste.
The results of the study were measured. The
presence of allergic reactions to hygiene products
was also determined using the R. Voll drug test.
The R. Voll drug test was used for determination.
The results of the use of toothpaste with Karlovy
Vary salts in patients with chronic systemic
catarrh. The use of toothpaste with Karlovy Vary
salt in patients with chronic catarrhal gingivitis
led to a 2.3-fold decrease in the PMA index. The
PMA index decreased 2.3 times, the Green-
Vermilion hygiene index - 3.4 times, the
interdental papillary bleeding index PBI - 2.7
times.
INTRODUCTION
Inflammatory periodontal disease is a fairly common lesion of the oral cavity.
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Pages: 187-195
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Inflammatory periodontal diseases are a fairly common lesion of the oral cavity, the incidence of which
reaches 98% [6]. Initial Clinical manifestations are manifested in the form of halitosis and bleeding.
Halitosis and bleeding
It often manifests itself in the form of bleeding gums. At this stage, timely diagnosis is necessary,
Rational treatment and preventive measures will
contribute to the patient's recovery. they contribute to the patient's recovery. A special role in
successful treatment Preventive measures play a special role in successful treatment. Oral hygiene,
choice of means and methods. It is the choice of Basic hygiene products used in complexes. One of the
main hygiene products used in the complex treatment of inflammatory periodontal diseases is
toothpaste with an anti-inflammatory effect. Today there is a wide range of toothpastes.
The competition for such pastes is very fierce. New products must have an effective composition and
New products must have an effective composition,
they should be liked by the consumer and be useful for treatment and prevention. Karlov toothpaste.
DAR toothpaste manufactured by DENAS-MS (Russia) contains natural ingredients. Karlovy Vary
mineral salts. For 400 years, irrigation of the oral cavity with spring water from a Czech resort has been
improving the condition of the gums and oral mucosa, speeding up the healing process and improving
the condition of the oral cavity.Improves the condition of the oral mucosa, promotes wound healing,
has anti-inflammatory properties and helps to cleanse the interdental spaces, prevents plaque
formation. It has been proven that she is. Induces regenerative processes in the oral cavity without
changing the pH level. Thyme oil is a natural ingredient that helps maintain fresh breath
and a pleasant smell after using toothpaste. It helps to keep fresh breath and a pleasant aftertaste after
using toothpaste. In addition, it reduces the sensitivity of the neck of the tooth, has an anti-inflammatory
effect and gives the Karlov Dar toothpaste a pleasant aroma. Mussel hydrolysate is a highly biologically
active product secreted by mussels. It is a highly active biological product.
It is a natural "cement". It is a natural "cement" contained in the shells of shellfish. As part of the
toothpaste, mussel hydrolysate penetrates into the micropores of the enamel and strengthens it, helps
prevent caries. Do not forget about the ingredients of toothpaste. The ingredients of toothpaste can alter
the regenerative processes of the epithelium of the oral mucosa and immunological reactions, as well
as cause allergic, toxic and immunological reactions. The development of allergic reactions is extremely
common [3, 5]. Therefore, individual tolerance should be evaluated to reduce the likelihood of side
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effects and allergic reactions. Reducing the likelihood of side effects and allergic reactions is a modern
urgent task of modern dentistry [7].
RESEARCH OBJECTIVES
To increase the effectiveness of therapeutic and preventive measures in chronic generalized gingivitis
[7]. In chronic generalized gingivitis Karlovy Vary toothpaste "Karlovy Vary". Mineral salt "Natural
freshness". Based on subjective and objective data Based on subjective and objective data.
MATERIALS AND METHODS OF RESEARCH
The study included 20 healthy patients aged 18-20 years. The participants of the clinical trial were
divided into The participants of the clinical trial were divided into two groups. 10 people in each group:
group 1 - healthy patients (comparison group Comparison group) and group 2 - patients with chronic
generalized gingivitis (ICD-10 code K05.1). Groups). 7-14 days before the start of the study.
All participants received: specialized hygienic treatment of the oral cavity with the removal of the soft
tissues of the tooth Specialized hygienic treatment of the oral cavity with the removal of soft dentin ,
removal of supra-gingival tartar and polishing. Fluoridation of teeth, fillings and tooth enamel. All
volunteers should be trained in individual oral hygiene and recommend the Leonard dental cleaning
method. Each patient was examined for complaints, medical history and life history, an examination
was carried out and the condition of the teeth was determined. The KPU index and the gingivitis index
RMA were measured in each patient, Index of hygiene of green teeth, index of interdental bleeding index
of interdental papillary bleeding PBI. Then the device "DiaDENS-PKM" was used.
The diagnosis was carried out according to the method of R. Voll. Diagnosis and detection of hidden
pathologies was carried out according to the measurement method. CT scan of the lymphatic system,
LPS of the lymphatic system, LPS of allergy, LPS of connective tissue degeneration, LPS of the endocrine
system; all
All measurement points were located on the patient's arm All measurement points were located on the
patient's arm. Measurements were carried out with the right and left hand. Measurements were carried
out with the left hand. Each patient was
A test for the compatibility of toothpaste.
Karlovy Vary toothpaste using R. Voll's dosing test. Dosing test
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It consists in recording changes in electropuncture parameters when a passive electrode is inserted
into the circuit.
The passive electrode is inserted into the circuit of the passive electrode of the subject. Plastic bioinert.
The flask. Five grams of Karlov-Dahl toothpaste were placed in a flask. Toothpaste "Karlov-Dahl"
(Weighing was carried out using electronic scales Trony. Trony electronic scales, model. T-KS2003EG).
The use of Karlov-Dahl toothpaste. The use of Karlov Dar toothpaste in each examined patient was
allowed on the basis of a complete examination.
(clinical examination and electropuncture). The criterion for the correctness of the drug test was the
normalization of the indicators of the four meridians.
That is, the value in the corridor is from 50 to 70. Getting the indicators into the 50-70 corridor and
eliminating the "down" arrow of most indicators.
The number of indicators. Due to a certain subjectivity When implementing the above-described
methodology , the studies were conducted in all cases by
the same doctor. A computer system. The operating system Microsoft Windows 10 and the
electrodiagnostic device "DiaDENS-PC" were used.
The included software. The software "DiaDENS-PC" was used (a product of the company "DENAS. MS").
The obtained results of all studies were statistically processed using the Vortex 7.0 program. Using the
Vortex 7.0 program
, the arithmetic mean was determined by the method of variational analysis, and the Student's t-test
was used to determine confidence intervals. Determination of confidence intervals. By default,
confidence intervals are determined by the program. For the Vortex 7.0 application, the confidence
interval is set to <0.05.
This is a 95% probability. Make sure that the percentage value is within the range.
Package. Dental examinations. Preliminary inspection, after the first application,
12 hours after application - 7 days, 14 days and 1 month to determine the rate of plaque formation.
After 7 days, 14 days and 1 month. Cytomorphological studies [2]. Cytomorphological studies [2] were
conducted at the Department of Histology of the Federal State Budgetary Educational Institution.
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The study was conducted at the UGMU University. Buccal epithelial scrapings were taken from all
patients before, 7 days, 14 days and 1 month after the start of toothpaste application. Before, 7 days, 14
days and 1 month after the start of the toothpaste application. After 14 days of Scraping. Stained with
Pappenheim stain, 500 cells. Absolute values and percentages. Absolute and percentage of epithelial
cells (basal, parabasal, intermediate and superficial). and keratin scales. The parameters of maturation
and differentiation of epithelial cells were determined.
The absolute number of leukemic cells in 25 visual fields. The absolute number of leukemic cells and
connective tissue and the index of inflammation-destruction (according to A.S. Grigoryan) [4]. Analysis.
Spontaneous formation of bacterial colonies [1]. Epithelial cells were analyzed by counting 100
epithelial cells.
100 epithelial cells were included. Adhesion potential (10 or more microorganisms). The percentage of
adhesion. The average number of microorganisms and adhesins per 100 epithelial cells was
determined.
The rate of adhesion per epithelial cell (index of colony formation of buccal epithelium). (epithelium).
Statistical data processing Statistical data processing
was carried out using the Microsoft Excel program. The results of the study and their discussion The
results of the clinical study At the time of initiation of treatment, patients presented the following
symptoms Complaints of bleeding gums (36%), the presence of dental deposits (21%), unpleasant
halitosis (32%).
halitosis (32%). An objective examination confirmed the data of the patient survey. Clinical examination
revealed inflammatory changes in the gums in some patients.
Inflammatory changes were observed in the papillary and marginal gum in some patients, but gum
attachment was not impaired. Inflammatory changes were observed in the papillary and marginal gum,
but the attachment of the gum was not impaired. Dental surfaces Cervical and alveolar regions Soft
plaque from the approximal surfaces of the teeth. All patients The index was evaluated in all patients:
CPI index - 5.7 ± 0.4, oral hygiene index The Green-Vermilion oral hygiene index was 1.52 ± 0.32, the
gingivitis index RMA was 32.85 ± 2.44%, the interdental bleeding index The index of interdental
papillary bleeding PBI is 1.46±0.26 1.46±0.26. Occlusion disorders were detected in 25
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identified in cases. A week after the first treatment. All patients who used the new Karlov Dar toothpaste
In all patients who used Karlov Dar toothpaste, oral hygiene improved and the evaluation index
significantly decreased. Oral Hygiene Index
The index of oral hygiene in green vermilions decreased by an average of 20% and amounted to 1.20 ±
0.16. The value was 1.20 ± 0.16. Patients noted that the cleansing ability of the paste The feeling of
freshness in the mouth persisted for several hours. it lasted for several hours. Besides. The paste is
homogeneous and foams well, after use there was no itching or burning of the oral mucosa. Examination
of the oral cavity and According to the results of the oral cavity examination and the index assessment,
the RMA was 31.76 ± 2.10%, and the PBI was 1.39 ± 0.18. Two weeks after the start of the toothpaste
application, the patient did not complain, there was a decrease in bleeding gums. The condition of the
oral cavity was satisfactory. Oral hygiene was good. Oral hygiene, swelling and hyperemia of the mucous
membrane were not observed. The results of the index assessment. IG - 0.76 ± 0.14, PMA - 24.52 ±
1.67%, pbi - 0.88 ± 0.16.
A month after applying the paste, the PMA index clinically decreased as follows.
14.38 ± 1.50%, pbi - 0.55 ± 0.12; GreenVermilion index was 0.45 ± 0.12.
The suggested one was good. The results of the weekly questionnaire. 89 %.
- 89% - The toothpaste is homogeneous. Foams well, - 92% - the toothpaste is hygienic.
CONCLUSIONS
1. As a result of the use of Karlov Dar toothpaste in patients with chronic generalized gingivitis, a
decrease in the values of the PMA index was observed by an average of 2.3 times, the Green-Vermillion
hygienic index by 3.4 times, and the bleeding index of the interdental papillae PBI by 2.7 times. 2. An
individual test of the compatibility of toothpaste using the R. Voll drug test showed that the paste
does not cause allergic reactions. 3. The use of Karlov Dar toothpaste causes an increase in the
percentage of epithelial cells of the terminal stages of differentiation, a decrease in the activity of the
inflammatory process,
an increase in the nonspecific resistance of the mucous membrane, which is reflected in the increased
bacterial colonization of cells.
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