The success of modern dentistry is largely due to the development and implementation in practice of new tools and methods that allow painlessly carry out long and large — scale interventions in the oral cavity. The most effective and safe way of anesthesia on an outpatient dental reception is local anesthesia (M. G. Panin, 1969; A. F. Bizyaev, 1998; S. F. Gritsuk 1998; S. A. Rabinovich, 2000; R. S. Brown, 1994; S. Malamed, 1994, 1997; etc.). For the time being. The most effective of them are recognized drugs created on the basis of articaine, due to the peculiarities of its pharmacokinetics and pharmacodynamics (H. Lemay, 1984; R. Rahn, 1996, S. Malamed, 1997; A. J. Petrikas, 1997; L. A. Grigoryants, A. P. Shafransky, 1999; E. V. Zoryan, E. N. Anisimova, 2002; S. A. Rabinovich et al., 2005, 2006; E. V. Zoryan, S. A. Rabinovich, 2005; S. A. Rabinovich, E. V. Zoryan, 2006; etc.).The articaine containing products produced by various foreign companies and is known for its proprietary trade names: al-fakin (Densply, France), Articaine of INIBSA (Inibsa, Spain), Prilocain (Russia), Primaquin (France), Septanest (Septodont, France), Ubistesin (ZM ESPE, Germany), Ultracain (Sanofi-Aventis, Germany), Cytokeratin (Italy). The main component of all these drugs is a local anesthetic — articaine, which determines, on the one hand, the General features of the action of all these drugs, and on the other-their distinctive features in comparison with drugs created on the basis of lidocaine or mepivacaine. Articaine, lidocaine and mepivacaine are international nonproprietary names (INN), which are indicated along with trade names (E. V. Zoryan, S. A. Rabinovich)
