Efficiency of pharmacotherapy in combined treatment of extended purulent peritonitis

Despite the progression and improvement of methods of surgical interventions, the number of peritonitis spread among emergency operations performed is 20-35%, of which 19-60% of cases end in mortality. The main key factor in the etiopathogenesis of peritonitis remains the bacterial link. At the same time, the appearance of highly virulent microflora contributes to the antibiotic resistance of drugs associated with the presence of beta-lactamases [1; 2; 6; 7].