«Современные тенденции в психиатрии и медицинской психологии:
интегрированный подход к социальной психиатрии,
лечению аддикций и повышению комплаенса»
I Международная научно
-
практическая конференция
«Исмаиловские чтения»
34
С
LINICAL FEATURES OF THE COURSE OF CEREBRAL PATHOLOGY
IN PATIENTS WITH ENDOGENOUS DISEASES
Irmukhamedov T.B.
Tashkent Pediatric Medical Institute
Annotation.
Mental disorders in somatic non-infectious, infectious diseases,
and intoxications are psychoses. The main role in their occurrence is played by
exogenous factors. Psychosis from Greek means a disturbed mental disorder
accompanied by pronounced mental activity while mental reactions are
contradictory to the real situation, which significantly affects the perception of the
real world as well as the disorganization of behavior.
Objective
of the research
To study the features of the dynamic clinical course of paranoid
schizophrenia combined with chronic neurological and somatic diseases.
Material and methods of the research
53 patients with paranoid schizophrenia (F20.XX according to ICD-10) aged
from 38 to 65 years, combined somatic pathology without exacerbation were
examined. The duration of the somatic disease was at least 6 years.
Results
The study found that most often (15 patients
–
44.1 %) were diseases of the
cardiovascular system (hypertension, coronary heart disease). Diseases of the
digestive system: chronic hepatitis, cholecystitis, gastritis, and colitis were
detected in 10 cases (29.4 %). 5 patients (14.7 %) had respiratory diseases
(mainly chronic bronchitis). In the last place (4 patients, 11.8 %) were kidney
diseases: urolithiasis, and chronic pyelonephritis. The risk of coronary heart
disease among patients with paranoid schizophrenia is significantly higher in
women over 55 years of age (77.6 %), with concomitant somatic diseases
(hypertension, diabetes mellitus), overweight (44.4%), or underweight (33.3%).
In patients with paranoid schizophrenia, combined with cardiovascular diseases,
there is a similarity in PANSS indicators (the average value of positive symptoms
is 52 points). In the clinical picture, they have undistinguished delusional
symptoms (3 points), depressive symptoms predominate (with anxiety in
hypertension and apathy in coronary heart disease), and hallucinatory symptoms
(5 points) with a significant decrease in criticism (5 points) or a shallow defect
(average values of the scale of negative syndromes 46 points, anergy 46 points).
Encephalopathy of various origins
–
40% of patients with schizophrenia with
positive symptoms and 16.9% of patients with negative (p<0.05); birth trauma in
«Современные тенденции в психиатрии и медицинской психологии:
интегрированный подход к социальной психиатрии,
лечению аддикций и повышению комплаенса»
I Международная научно
-
практическая конференция
«Исмаиловские чтения»
35
the anamnesis-25% of patients with schizophrenia with positive symptoms and
7.7% of patients with negative symptoms. negative (p<0.05) increases the risk of
neurological complications in patients with schizophrenia with positive
symptoms and requires additional use of nootropic drugs. All patients have a
strong decrease in criticality and awareness of the disease (PANSS average
–
5
points) not only about mental illness but also concomitant somatic pathology.
This can lead to complications when prescribing psychotropic therapy, as well as
reduce the quality and life expectancy of this category of patients.
Conclusions
Thus, our research allowed us to identify the need for a differentiated
approach to the organization of care for patients with combined mental,
neurological, and somatic pathology and to determine the directions of treatment
and rehabilitation recommendations for use in practice by psychiatrists and
general practitioners.
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«Современные тенденции в психиатрии и медицинской психологии:
интегрированный подход к социальной психиатрии,
лечению аддикций и повышению комплаенса»
I Международная научно
-
практическая конференция
«Исмаиловские чтения»
36
9.
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аутистическими расстройствами." Российский педиатрический журнал 22.5
(2019): 284-285.
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CHARACTERISTICS OF VASCULAR DISEASES OF BRAIN IN PATIENTS WITH
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(2021): 13080-13085.
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(2021): 13080-13085.
