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FEATURES OF ECHOCG PARAMETERS IN CHILDREN WITH
TYPE 1 DIABETES MELLITUS WHO SUFFERED COVID-19
Mukhtor O.D. Student of II - Pediatric and medical-biological faculty
Referral pediatric case group 211
Supervisor: Associate Professor Sadirkhodjaeva A.A. Department of Propaedeutics
of Childhood Diseases, hematology TashPMI
Introduction.
Diabetes mellitus (DM) is one of the main problems of scientific and
practical medicine around the world. DM is a disease with a chronic metabolic disorder that
affects all stages of childhood in one way or another. The manifestation of diabetes begins in the
womb and affects newborns, babies, children. Its cardiovascular complications account for a
significant portion of morbidity in such an active age due to metabolic impairment, associated
dyslipidemia, atherosclerosis, hypertension, and autonomic dysfunction.
Purpose of the study.
Study changes in EchoCG in children with type 1 diabetes mellitus
who have undergone Covid-19
Research materials and methods.
The paper presents an analysis of the results of
observation, instrumental methods of studies of 49 children with type 1 diabetes in children who
have undergone Covid-19, aged 4 to 18 years, the comparison group was 65 children with type
1 diabetes, the control group was 30 practically healthy children of similar age.
Results of the study and their discussion.
Doppler EchoCG in 20.1% of children from
the first group revealed diastolic LV dysfunction by the ratio of flow rates in the early and late
diastolic LZh<1,0 filling phases. Based on morphometric studies of children with diastolic LV
dysfunction, myocardial hypertrophy with increased diastolic rigidity was observed, manifested
by an increase in myocardial volume, thickness of the interventricular septum and posterior LV
wall, a decrease in the index of the final diastolic volume with a tendency to increase the size of
the DP.
Central hemodynamics in children of the comparative group is expressed by increased
CR (43,6±2,0ml at 34,2±0,9 mL in the control group, p < 0.001) with an increase in HR (87 per
min at 72 per min in the control group, p < 0.001). In group 1, 77.1% of children had a
hyperkinetic type of central hemodynamics (p < 0.001 to group 1). In the comparison group, the
maximum LV ejection fraction was stated (69% at 65% in the control group), EF was 69%,
stating an increase in LV myocardial contractility. Children with diabetes mellitus who have
undergone COVID-19 had low EF rates up to 59,9±1,9% (p < 0.01).
When determining the mass of myocardial (MM) LV, the examined children of the 2nd
group showed a tendency to reduce MM (68,1±2,0), while in children who underwent COVID-
19 these values tended to increase depending on the parameters of the control group (76,8±1,14
g).
Conclusions.
Thus, according to EchoCG data, it was established. that one of the early
signs in the development of diabetic cardiopathy is a decrease in the rate of LV myocardial
relaxation against the background of pathological types of transmitral diastolic blood flow curves
and a decrease in myocardial contractility. The established mutual agreement of the disease and
EchoCG indicators, which leads to the depletion of energy reserves in the compensation of
myocardial functions and the development of already irreversible changes in the microstructures
of the heart muscle
References:
1.
Мирзаева, У. З., С. И. Исмаилов, and Х. К. Насырова. "НАРУШЕНИЕ
УГЛЕВОДНОГО ОБМЕНА У ПАЦИЕНТОВ COVID-19." BARQARORLIK VA
YETAKCHI TADQIQOTLAR ONLAYN ILMIY JURNALI 2.9 (2022): 117-122.
