Meaning and role of mycoplasma infection for children with bronchial asthma small studied. By us was inspected 39 children with BA in age from 2 to 14, from them 27 (69,2%) boys and 12 (30,8) girls. Obtained data from PChR testing is shown: among the children of patients with BA for 33,3% (13/39) patients found out M. pneumoniae.; for 66,7% (26/39) patients and for all children of control group M. pneumoniae. it is not discovered (table.№1). For children in a range 2-5, the more than half (53,8%) of children-asthmatics was got positive results of PChR; among the investigated children in age 6-14, only at 46,2% patients had M. pneumonia. Except it, among patients with BA, for 69,2% boys and 31% girls made the positive result of PChR, and correlation of sexes was made by 2,2: 1.
Atkinson T.P., Balish M.F., Waites KB. Epidemiology, clinical manifestations,pathogenesis and laboratory detection of Mycoplasma pneumoniae infections. - FEMS Microbiol. Rev.- 2008.-№32(6).-С.956–73.
Cengizlier M.R., Misirlioglu E.D. Evaluation of risk factors in patients diagnosedwith bronchial asthma. AllergolImmunopathol (Madr).-2006.-№34(1).-С.4–9.
Esposito S., Blasi F., Arosio C., Fioravanti L., Fagetti L., Droghetti R et al.Imporance of acute Mycoplasma pneumoniae and Chlamydia pneumonia infections in children with wheezing. EurRespir J.- 2000.-№16(6).С.1142–6.
Lee KY. Pediatric respiratory infections by Mycoplasma pneumoniae. Expert. Rev AntiInfect Ther.- 2008.-6(4).С.509–21.
MacDowell AL, Bacharier LB. Infectious triggers of asthma. Immunol AllergyClin North Am.- 2005.№25(1).-С.45–66.
Maclennan C, Hutchinson P, Holdsworth S, Bardin PG, Freezer NJ. Airwayinflammation in asymptomatic children with episodic wheeze. PediatrPulmonol.- 2006.-№41(6).-С.577–83.
Narita M. Pathogenesis of extrapulmonary manifestations of Mycoplasmapneumoniae infection with special reference to pneumonia. JInfectChemother.-2010.-№16(3).-С.162–9.
Agapova. O. Bronchial asthma: receptor interactions and not only ... On the search for new approaches in tactics and treatment and ongoing research. // Honey. gas. - 2017. - No. 74. - S. 12-13.
Bazhenov EE, Akhmedov VA, Ostapenko VA Clinical and pharmacological foundations of modern pulmonology: a textbook for the system of postgraduate professional education of doctors. / Moscow: BINOM. Knowledge laboratory, 2015.-55 p.
Belevsky AS Global strategy for the treatment and prevention of bronchial asthma (revision 2014) - Moscow: Russian Respiratory Society, 2015. - 148 p.
Geppe N.A. The urgency of the problem of bronchial asthma in children // Pediatrics. - 2012. - T. 91, No. 3. -S. 76-82.
Zakharova I.A., Belevsky A.S. Possibilities of treating virus-induced bronchial asthma // Bronchial asthma. - 2017. - No. 3. From 3-5.
Ilyenkova NA Concentrations of cytokines in bronchial asthma in patients depending on the degree of disease control // Doctor.RU. - 2018. - No. 4. - P. 44-47.
Kostinova M.P., Chuchalina A.G., Guide to clinical immunology in respiratory medicine / Moscow: ATMO, 2016. - 128 p.
Kostromina V.P., Strizh V.O., Matvianko Yu.O., Rechkina OO, Yaroshchuk L.B., Doroshenkova A.S. Clinical-and-nological criteria for differential diagnosis of bronchial asthma and bronchitis with broncho-obstructive syndrome in children // Asthma and allergy. - 2012. - No. 3. - S. 24-27.
Kupaev V.I. Cough variant of bronchial asthma // Asthma and Allergy. - 2018. - No. 3. From 13-15.
Kurbacheva OM, Pavlova KS Phenotypes and endotypes of bronchial asthma: from pathogenesis and clinical picture to the choice of therapy // Russian Allergological Journal. - 2013. - No. 1. - S. 15-24.
Lebedenko A. A. Analysis of the association of polymorphic variants of growth factors genes with the risk of developing bronchial asthma in children // Pulmonology. -2018- Vol.-28. No. 1. S. 7-12.
Marshalko O.V., Karpovich A.I. Therapy in 3 parts., Study guide / Minsk: RIPO, 2016 - Part 1: Pulmonology. - 2016 .-- 202 p.
Smolnikova M.V., Smirnova S.V., Ilyenkova N.A., Konopleva O.S. Immunological markers of uncontrolled course of bronchial asthma in children // Medical Immunology. - 2017. Vol.19, No. 4. S. 453-460.
Starostina L.S. Acute respiratory viral infection in children with bronchial asthma // Otorhinolorhinogology and Pulmonology. - 2017.- No. 3. 59-64.
Chernussky V.G., Odinets Yu.V., Morozova A.D. The influence of the alpha-blocker pyrroxan on the parameters of bronchial patency in children with bronchial asthma // Medicine of the Year and Tomorrow. - 2010. - No. 1. -S. 118-120.
Chernysheva OE, MODERN PREDICTIONS ON THE PATHOGENESIS OF AD IN CHILDREN "Child's Health", 2014 - ISSN 2224-0551 ¹ 5 (56) • 2014.