All articles - Neuroscience and Neurology
Number of articles: 594
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Тройничный нерв, пятая пара черепно-мозго вых нервов является самым крупным из 12 пар че репных нервов. Он относится к нервам смешанно го типа, включает чувствительные и двигательные волокна. Тройничный нерв берет свое начало в по лости черепа, в Гассеровом нервном узле. От этого узла отходит чувствительный корешок нерва, ко торый почти сразу делится на 3 ветви. Они выхо дят на поверхность через естественные отверстия в костях черепа и обеспечивают чувствительность лица к прикосновению, боли, теплу и холоду. I ветвь иннервирует лоб, бровь и глаз, II ветвь от вечает за чувствительность щеки, носа, верхней губы, верхней челюсти и неба, III - охватывает подбородок, нижнюю губу нижнюю челюсть. -
In recent years, the incidence of ischemic stroke has increased everywhere. This fact is explained by the increase in the number of elderly people and the prevalence of risk factors for stroke, such as arterial hypertension, diabetes, obesity, heart disease, etc., more than 80% of survivors are disabled. To date, neuroprotective therapy is the most important treatment in the treatment of this disease, and this article really describes its improving properties. -
Predictive study of penetrating ability 5% glucose solution into insulin- dependent organ cells mice exposed to ionizing radiation.The article reflects the results of an experimental study of the effect of ionizing radiation on the organs of animals of 30 intact opposite-sex BALB / c mice, 15 individuals of each sex. The age of the animals ranged from 2 to 3 months. Body weight from 18 to 22 grams.
Medicine and innovations -
эашагкапа siaic mcuicai insuiure, затагкапа. uzocKisian In the modern medical literature, discussions continued about neuropathies of the facial nerve in children, disease factors, clinical and neurological features, the severity of the course, the difficulties of diagnosis and prognosis of the disease. The work is devoted to the analysis of the neuropathy of the facial nerve in children and adolescents, depending on the clinical forms of the disease, using electroneurosympathetic indicators, the latency period, the blinking reflex and the nature of the lesion of the facial nerve accompanied by pain syndrome. -
Features of psychopathological and autonomic disorders in patients with chronic pain syndrome with radiculopathies of compression-ischemic genesisIn patients with radiculopathies of various origins, along with chronic pain syndrome (CHS), psychopathologi-cal and autonomic disorders are observed. In groups of patients with radiculopathies, the state of asthenia, anxiety, and autonomic changes was studied using psychological scales (2). Research on the Spielberg-Khanin scales of reactive and personal anxiety revealed a fairly high level of anxiety. The identification of mild and moderate depression on the Beck scale was especially significant. The results of the Kerdo index indicated damage to the autonomic nervous system in all patients, with a predominance of parasympathicotonic manifestations.
Doctor's Herald -
Features of comorbid anxiety-depression disorders and personal changes in type 2 diabetes mellitusThis article describes the polymorphism of mental disorders in patients seeking help in medical institutions of a somatic profile, is high. According to the WHO, more than half of patients suffering from moderate to severe somatic diseases have some kind of mental disorder. High prevalence, chronic course of the disease, polyetiology, polymorphism of somatic and mental disorders make diabetes mcllitus the most suitable model for the study and systematization of mental disorders in somatic patients.
Doctor's Herald -
PATHOGENETIC MECHANISMS AND CLINICAL VARIANTS OF PAIN SYNDROME IN PARKINSON’S DISEASEThe main features of Parkinson's disease arc the progressive nature and variety of motor and non-motor symptoms. A number of diverse non-motor symptoms develop, which often go unnoticed by neurologists and lead the patient to such specialists as urologists, ophthalmologists, therapists. Undiagnosed, these symptoms escalate, leading to frequent hospitalizations and reducing the quality of life of patients.
Doctor's Herald -
MORPHOLOGICAL CHANGES IN THE SPLEEN TISSUE OF LABORATORY RATS ON THE THIRD DAY AFTER A TRAUMATIC BRAIN INJURYLaboratory studies were conducted on 26 white mongrel rats of 3 months of age. This study was conducted three days after receiving a traumatic brain injury. The animals were fixed on a device made by hand in the form of a vehicle on wheels, the fixed animals were accelerated on the vehicle and hit the wooden barrier with the frontal part of the head. The speed of the vehicle was 6.7 km per hour. As a result of this experiment, two rats died on the spot. In 3-month-old rats, during the experiment, it was revealed that there were no macroscopic changes outside the organ, but there were some changes in the tissue structures of the white and red pulp of the spleen.
Doctor's Herald -
ROLE OF POLIMORPHISM OF GENE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF), HYPOXIA INDUCED FAKTORA-1Α (HIF-1α) AND INTERLEUKIN 17A (IL-17A) IN AGGRESSIVE PITUITARY ADENOMASPituitary adenomas are considered benign, however, in 20-50% of cases they have an aggressive course. The main criteria for aggressiveness arc frequent recurrences after surgical adenomectomy, resistance to traditional therapy, and massive invasion into nearby structures. The aim of the study was to study the molecular genetic features of invasive aggressive pituitary adenomas (APA). Gene polymorphism of VEGFA, HIF-la, and IL-I7A have been studied in 81 patients (main group) with invasive and non-invasivc pituitary adenomas (main group) and 83 healthy (control group). As a result of the study, it was found that the frequency of occurrence of the studied polymorphisms is more often observed in invasive adenomas and the detection of genotypes varies depending on the course of APA.
Doctor's Herald -
It is known that the thymus gland is one of the organs responsible for the main immunity in the body. The thymus gland undergoes evolutionary influence after the age of 14, which leads to a decrease in the body's immune reactivity and a decrease in the protective reaction to any external influences. With age. a person becomes more susceptible to chronic diseases. It should be noted that natural evolutionary processes in the thymus develop early due to morphometric changes observed in the thymus gland after TBI. This leads to premature aging of the body, increased susceptibility to various infectious diseases due to a decrease in immune reactivity. That is. complications from the thymus gland observed after TBI lead to an increase in mortality in young people. -
THE EFFECTIVENESS OF OXYBRAL IN THE CORRECTION OF LIPID PEROXIDATION DISORDERS IN CHILDREN WITH THE CONSEQUENCES OF PERINATAL DAMAGE TO THE NERVOUS SYSTEMThe results of researches have shown, that at children with prenatal damages CNS reveal significant infringements in processes a lipid peroxidation (LPO), which is possible were characterized as decreasing and in some cases their misbalancc. The assignment of oxibral to children with prenatal damages of CNS alongside with normalization of parameters a LPO to faster improvement of neurological symptoms: children become quiet, active, the dream normalizing. Intra skull pressure on a background of prescription Oxibral was reduced much faster. The opportunity of correction neurological infringements with oxibral opens prospect of rehabilitation and promotes significant to reduction of percent of children with the residual phenomena of prenatal damages CNS.
Doctor's Herald -
The course of Meniere’s disease is observed in every second patient and even more often. Despite the high frequency of monosymptomatic development of the disease, many authors regarded this as an atypical course of Meniere’s disease and even distinguished its cochlear and vestibular forms. In our opinion, no convincing arguments in favor of this point of view are given. 52 people were examined who underwent otorhinolaryngological examination, detailed audiometric and vestibulometric examination. In each of the examined groups of patients, a decrease in excitability on the side of the lesion was the most typical reaction of the vestibular system to the hydrops of the labyrinth. -
MODERN ASPECTS OF ELECTROENCEPHALOGRAPHIC CORRELATES OF SOME COMPLICATED FORMS OF MIGRAINEThe aim of the study was to study the electroencephalographic correlates of the brain in some complicated forms of migraine. 133 (100%) patients with migraine were under observation, 66 (49.6%) with migraine status, 67 (50.4%) with chronic migraine. A 16-channel apparatus of the company «Neurosoft» carried out EEG. Thus, neurophysiological parameters of EEG were objective indicators of complicated forms of migraine, determining the zoning of the pathological process, the presence of exacerbation and aura.
Doctor's Herald -
Features of cognitive frustration at chronic ischemia of the brainThe results received by us specify that at chronic ischemia of the brain the phenomenon of corticosub-cortical and corticocortical dissociation observed in the majority of clinical cases is the cornerstone of cogni-tive frustration. The leading role at this pathology presumably belongs to defeat of white matter of a brain, es-pecially bonds of frontal departments with other structures of the central nervous system, especially at patients with AG.
Journal problems of biology and medicine -
The article is intended for pediatricians, pediatric neurologists and general practitioners. It provides data on the possible causes of convulsive syndrome in children, as well as tactics and the algorithm of management, care for this category of patients by general practitioners. An integrated approach allows for timely and correctly identify of the cause of convulsive activity in children of different ages, based on objective clinical, laboratory and instrumental (EEG. CT, MRI, etc.) research methods. -
PERINATAL DAMAGES OF THE CENTRAL NERVOUS SYSTEM AND THEIR CONSEQUENCES (REVIEW OF LITERATURE ON EPIDEMIOLOGY, CLASSIFICATION AND TERMINOLOGY)Hypoxic-ischemic lesions of the central nervous system (CNS) in the perinatal period (synonyms - perinatal asphyxia, hypoxic-ischemic encephalopathy, congenital craniocerebral trauma) are characterized by symptoms of secondary ischemia of the nervous system, which develop as a result of chronic or utkir hypoxia (asphyxia) and are confirmed by clinical and laboratory tests. According to the criteria of the organization for the protection of health of the whole world for newly born jackals and births, new cul kilingai with tsgishli for fertility is carried out according to the conditions in the Kui, that is, in the period of 22 weeks the weight of the child should be at least 500 gr or less (with kupson), the height of dirty [2, 4, 5, 19, 22, 23]. The possibilities of living with a child who was born out of wedlock a few decades ago are very rare bulsa, apply now
Doctor's Herald -
Treatment of satanic States depends on the reasons that make it thick. Quickly identify the causes and eliminate it in the uz vaccine allows you to burden some types of satanic cases without uttering an anticonvulsant (anti-Satanic) treatment. Recommended weight loss anticonvulsant therapy should be avoided, both choosing them causes feverish attacks and is prescribed carob in Kharkiv. In the first place, measures to eliminate hypoxia are established. During satiation, the demand for oxygen content increases by 5 times. Therefore, for the first time it is necessary to adequately provide oxygenation of the mine. To do this, the marrow is given with the help of an oxygenated nasal catheter, a enema, a mask, an oxygen chamber, when it is necessary to find (when breathing disorders, satiety attacks last more than 30 minutes), the trachea is intubated. Adskvat oxygen gives the effect of treatment to the bruise burden, it is better to use a transcutaneous monitor (pulsometer) to clarify the vision of the deposit into oxygen. The factors that lead to them in cases of hypoxia in the aloxia, which is accompanied by CyHi-pa metabolic disorders, lead to weight loss. -
The review presents current data on the problem of sleep disorders in pregnant women, as well as the impact ot sleep disorders on the course of pregnancy, the development of obstetric complications and birth outcomes. -
Variants of the clinical course of the effects of perinatal hypoxic lesions of the central nervous systemThe objective of this study was to identify variants of the clinical course of central nervous system thera- py. The examined children were divided into groups with coarse focal lesions such as cerebral palsy and chil- dren with elevated functional impairment and minimal brain dysfunction. All children underwent a clinical and neurological examination of the neurophysiological EEG, TCDG. Identified brain immaturity, epileptiform ac- tivity, reduced blood flow to the vessels of the carotid pool
Journal problems of biology and medicine -
Comprehensive assessment of postural control in stabilometric studyThe paper presents data on the features of the manifestation of the syndrome of falls in patients 65-74 years. Since it is known that from 50 to 70 % of all falls in the elderly and senile age occur during walking, we conducted a comparative analysis of the parameters of walking in patients with and without falling syndrome. Estimation of parameters of the walk was carried out with the help of computerized stabilometric complex "Smart Equitest Balance Manager". The decrease in adaptive abilities to complex motor acts in elderly women with fall syndrome was revealed. In addition, a significant change in the indicators "reversal time" and "fluctu- ation in the reversal" of the test "Rapid reversal" in women 65-74 years of fall syndrome, which indicates a decrease in visual and vestibular information in balance control, deterioration of neurophysiological mecha- nisms and dysfunction of the musculoskeletal system
Journal problems of biology and medicine -
Comparative evaluation of the pre-stroke forms of cerebrovascular pathology in young personsThis article presents the data of a comparative analysis of the clinical symptoms of the pre-stroke forms of cerebrovascular pathology on the background of hypertensive disease. It was found that a significant pro- portion of young patients have a clinical manifestation of the CVP on the background of HD. The development of CVP on the background of HD does not depend on the duration of the disease, but largely depends on the severity of the etiological vascular disease and the level of blood pressure. Patients with hypertension fall into the field of the view of neurologists later, and therefore, the available cardiovascular manifestations underes- timated, causing the performance of treatment of CVP with some delay and the risk of stroke is also increased
Journal problems of biology and medicine -
A case from expert practice is described that is associated with an unrecognized, during life, stratified aneurysm of the ascending aorta in a 19-ycar-old man who was in a specialized boarding school for more than 10 years and was repeatedly examined by doctors. The disease had an acute course. The rupture of the aneurysm caused cardiac tamponade. which was the cause of death of Mr. U. The case is of interest to clinicians of various specialties and practitioners, GPs. -
Features of cerebral hemodynamics and concentration of neuron-specific enolase in the expert assessment of traumatic brain injury in children and adolescentsThis work describes results of studying of neurologic status, cerebral hemodynamic and concentration of neurospecific Enolase as a marker of injury of neural tissue in children during expert assessment of cranio- cerebral injury. Were examinated 68 children from 8 to 18 years old , who were treated in the department of traumatology, orthopedics and neurosurgery of TashPMI. It was established that improving the accuracy of forensic medical diagnostics in children of different ages with СBI, it is advisable to include assessment crite- ria in determining the severity of injury to age-dependent features of cerebral hemodynamics and neurospecific Enolase concentration.
Journal problems of biology and medicine -
Diagnostic meaningfulness of cochleobestibular violations for patients with illness of meniere23 patients were plugged in research, suffering БМ with the hemilesion of internal ear. In a interap-proachable period a voice-frequency threshold audiometry, video-nystagmography, caloric test, videoimpulsive test, was conducted all patients. For БМ absence of the hidden spontaneous nystagmus is most characteristic, however the positive test of shaking of head can register oneself. The presence of asymmetry of results of calor- ic test and normal values of data of videoimpulsive dough are also characteristic in period. At the analysis of character of decline of rumor and coefficient of asymmetry in the labyrinth (CASTLE) revealed a tendency to increase hearing thresholds with increasing CASTLE
Journal problems of biology and medicine -
Results of clinical and neurological examination and treatment of children with cerebral palsySurveyerd children with cerebral palsy. The division was according to the forms of the disease and de-pending on the treatment received. Traditional treatment included all previously known medical and physio-therapeutic procedures. The results indicated that the traditional treatment was insufficiently effective, which was determined by the persistence of a high frequency of motor disorders and necessitated the use of more ef-fective rehabilitation methods
Journal problems of biology and medicine
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