All articles - Pathology
Number of articles: 179
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ВЫСОКИЕ ГУБЫ И НЕБО У ДЕТЕЙ С ВРОЖДЕННОЙ ХЛЫСТОВОЙ ТРАВМОЙ ПАТОЛОГИЯ ПОЛОСТИ НОСА И БОКОВЫХ ПОЛОСТЕЙ НОСА ЭНДОСКОПИЧЕСКАЯ ДИАГНОСТИКАВ данной работе было проведено подробное эндоскопическое исследование полости носа и придаточных пазух носа у детей с врожденной расщелиной верхней губы и неба на этапах хирургического лечения врожденных пороков для определения влияния, данного аномалия на развития патологии в этих органах. Это, в свою очередь, увеличивает успешность раннего выявления и реабилитации патологических процессов в полости носа и придаточных пазух носа.
Medicine and innovations -
INTERRELATION OF TEMPOROMANDIBULAR DISORDERS WITH THE OCCLUSAL ALTERATIONS OF PRIMARY DENTITION114 children with certain pathological changes in the dento-maxillary system with a permanent bite were taken under medical supervision for orthodontic treatment. Examination of the temporomandibular joint of patients with muscular-articular dysfunction was carried out by computer tomography (CT). In 71.4% of children with a distal bite, the head of the joint of the lower jaw is shifted up and back, while only in 28.6% of the head of the joint is located in the center. In 73.3% of children with a deep bite, the head of the joint of the lower jaw is displaced up and back, whereas in 26.7% of the displacement was not observed. According to our results, pathological bites occupy one of the main places in the pathogenesis of muscular-articular dysfunction of the mandibular joint, since displacement of the head of the joint of the lower jaw is more common with a distal and deep pathological bite.
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The article is devoted to the problem of restoring bladder functions in disorders of its central and peripheral innervation, issues of the so-called neurogenic bladder in spinal cord injuries. Despite numerous modem studies, bladder function, bladder innervation and the mechanisms of its coordinated activity, as well as their correction in spinal disorders, remain important issues of modem medical science and require their solution in the context of neurorehabilitation. -
Ray visualization of breast pathology in women depending on thyroid statusAnalyzed the results of X-ray sonography of 200 women with mammary gland pathologies. In women with mammary gland pathologies, thyroid hypothyroidism was noted in a somewhat prevalent percentage of observations, confirmed by radiometry and laboratory data. When ypothyroidism is determined by an in-crease in the number of observations of fibroaden and diffuse fibrotic mastopathies, characterized by pro-nounced fibrosis processes and a violation of regression of the glandular tissue. The reverse situation is ob-served in the occurrence of mammary gland cysts and normal tissue structure, the number of such observations in patients with hypothyroidism was significantly less than in patients without hypothyroidism. In women with hypothyroidism and without hypothyroidism, almost the same number of cases of breast cancer
Journal problems of biology and medicine -
This article deals with the complications of pregnancy in women with toxoplasmosis along with impact of it to the fetus and the course of pregnancy and its outcomes. The article gives advices about prenatal counseling and pre-conccptional care of women with toxoplasmosis. -
Quality of children and adolescents life with pulmonary tuberculosis depend- Ing on existence of the accompanying pathologyWork is devoted to studying of life quality parameters of children and adolescents with tuberculosis. Laboratory and instrumental methods examination of patients do not cover all aspect of tuberculous infection and do not allow valuing the condition of children and adolescents with pulmonary tuberculosis. At analysis of life’s quality there is full possibility to define the influence of the disease on physical, psychological and social aspects of the organism’s functioning. The analysis of quantitative indexes children and adolescents quality of life was conducted depending on accompanying pathology. For research was used the questionnaire of Pediatric Quality of Life Inventory - PedsQL. Questionnaire of PedsQL 4.0. includes 23 questions, incorporated in 4 scales. Every question has 5 variants of answers: "no", "hardly ever", "sometimes", "often" and "almost always", from which it is needed to choose one, most going near a situation.
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Modern views on the pathology of echinococcosis of the liverGeneral characteristics and prevalence of echinococcosis. Echinococcosis (Echinococcosis) (syn.: single-chamber (hydatidosis-echinococcosis, echinococcosis, echinicoccus granulosus, echinococcus disease - English) is a chronic disease in which solitary or multiple cystic formations develop in the liver, lungs, and much less often in other organs. The causative agent is the larval stage of tapeworm Echinococcus granulosus [23, 25]. The larval stage, growing, developing and living in the human body for decades, is represented by a round or oval cyst filled with liquid.
Journal problems of biology and medicine -
Prognostic evaluation of the risk of chronic pathologies among tubcontacts of children in educational institutions sanatoriumThe method of questionnaire survey of parents to study the characteristics of regime moments and conditions of education in 1175 of children in preschool tuberculosis sanatorium profile - the main group ( 220 children) and in preschool general types - the control group (955 children). Number of children in the study group with the breastfeeding duration of 12 months or more was 1,8 times less than in the control group; the number of children in the main group 1,1 times more educated in beshik, and those children with the period of stay from 1,5 to 2 years were 1,3 times more. On average, 60% of children received the information about the elements of a healthy lifestyle in the family, 32% - in the preschool education and 8,5% - as a result of watching television, using the Internet and children's publications. Almost 70% of the duration of outdoor exercise, diurnal sleep, watch TV and play on the computer of preschool chil- dren exceded hygienic standards. The increase in the risk of chronic disease in children tubcontacts consistently influenced by factors such as the duration of the games on your computer, feeding children breast milk, watching TV, outdoor activities and education of the child in beshik
Journal problems of biology and medicine -
Modern methods of treatment in children with chronic respiratory diseases pneumoniaThe usage of endobronchial autotransplantation of macrofagle cells of respiratory tract with poliox-idoniym, UFI, ozon fluid, lazer stimulation in children with chronic pneumonia positively influencedon the flow of inflammatory process in bronchus, that is has been confirmed by improvement of leukocyte index of intoxica-tion, endoscopic picture and cytologic bronchoalveolar – lavash fluid
Journal problems of biology and medicine -
Uterine malformations are congenital changes in the female genital organs, from underdevelopment to non—fusion of the Muller ducts with the formation of septa. According to some authors, abnormalities of uterine development occur in 25% of patients with disorders in the reproductive system. -
Hereditary, exogenous, multifactorial factors lead to the causes of anomalies in the development of female genital organs. The occurrence of genital malformations is attributed to the critical period of intrauterine development. It is based on the absence of fusion of the caudal sections of the paramesonephral Muller ducts, deviations in the transformations of the urogenital sinus, as well as the pathological course of gonad organogenesis, which depends on the development of the primary nocturnal. These deviations account for 16% of all anomalies. Anomalies of the development of the genitals often occur during the pathological course of pregnancy in the mother at different periods of pregnancy. These are early and late gestosis, infectious diseases, intoxication, endocrine disorders in the mother's body. In addition, anomalies in the development of female genital organs can occur under the influence of harmful environmental factors, occupational harmful effects in the mother, poisoning with toxic substances. Along with anomalies of the genitals, in 40% of cases there are anomalies of the urinary system (unilateral kidney agenesis), intestines (atresia of the anus), bones (congenital scoliosis), as well as congenital heart defects. -
Peculiarities of the acute of acute surgical pathology in hiv infected / aids patientsWith acute diseases of the abdominal cavity, 10 patients were hospitalized, 4 of them for acute appendi-citis, 3 for perforated ulcers, 1 for acute cholecystitis, 1 for gastrointestinal bleeding and 1 for infiltrates and phlegmon retroperitoneal space. Studies were conducted to analyze the immune status of patients taking into account the phagocytic activity of neutrophils, humoral and cellular immunity. HIV infection is not an excuse for refusing surgery in patients with acute surgical pathology. Observations showed that the HIV-associated infection burdens the course of the postoperative period. In patients, there is a prolonged phenomenon of intox-ication, pain, prolonged course of suppuration of the wound, as well as a difficult cleansing of the wound
Journal problems of biology and medicine -
The purpose of the work is to determine the frequencies, flow characteristics, aspects of treatment and prevention of trophic ulcers in children with spinal pathology. The development of a trophic ulcer was observed in 22 (25.3%) of 87 patients with various trophic disorders (symmetrical, asymmetrical limb atrophy, deformities in the joints of the lower limbs, disproportion of various parts of the body) among 252 children with spinal hernias (SH) 2016 years. Trophic ulcers arose in severe forms of SH and its combinations with other spinal cord anomalies, including in primary and secondary tetring syndrome. The article presents the clinical course, tactics and results of treatment. -
Importance of the level of urinary acid in the clinic and pathogenesis of acute coronary syndrome58 patients with acute coronary syndrome with asymptomatic hyperuricemia were examined. The results of the study showed that ACS is accompanied by an increase in the level of uric acid in the blood, which tends to decrease during the recovery of circulation in the ischemic myocardium, which characterizes the significant activation of the enzyme xanthine oxidase, which generates active forms of oxygen
Journal problems of biology and medicine -
Results vertebroplastik treatment of patients with fragility fractures at vertebral hemangiomasThe achieved results confirm a high pain-relieving efficacy of percutaneous vertebroplasty. A choice of vertebroplasy technique depends on a nature of pathology and peculiarities of vertebral anatomy. Application of cement based on calcium phosphate, bioceramic and bonemorphogenetic proteins improves the long-term outcomes of percutaneous vertebroplasty
Journal problems of biology and medicine -
Diagnosis of the combined pathology of the cancer of the bladder and benign hyperplasia of the prostateTo date, the diagnostic and therapeutic aspects of the combined disease of prostate adenoma and bladder cancer (RMP), which continue to attract the attention of urologists due to the constant improvement and introduction of new treatment methods, have not been sufficiently covered in the specialized literature. The question of the scope and sequence of interventions for these mutually aggravating pathologies remains still poorly developed. The detection of combined diseases in the preoperative period, if they are unexpectedly detected during or after adenomectomy, dictates the use of various tactical options. The literature data on this issue contain an analysis of a small number of observations and are evaluated very inconsistently.
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Acute esophagogastroduodenopathy in traumatic disease. Morphogenesis and private pathology of erosive damagesIn the study of biopsies obtained during fibrogastroduodenoscopy (43 men, 268 biopsies) and autopsy (9 people) affected by severe concomitant injury that centralization of blood circulation at the level of the digestive system that leads to local circulatory hypoxia with morphological changes ranging from mild reversible ischemia to necrosis were detected. Polietiology and monopathogenesis of shock in general and traumatic disease in particular, mean flexibility of mechanisms of alterative components development. Morphologically stressful, immunopathological and circulatory changes are expressed in the development of acute esophagogastroduodenopathy in form of acute erosions and ulcers with severe hemorrhagic component. Clinically it is manifested in the form of dynamic ileus, dyskinesia of the stomach and duodenum, pyloric insufficiency of duodenal bile reflux
Journal problems of biology and medicine -
According to world statistics, in recent decades, the frequency of chronic pathology among the child population has significantly increased. Almost 60% of children have chronic diseases. The prevalence of allergic [4], cardiovascular, bronchopulmonary diseases, diseases of the urinary system, gastrointestinal tract, and nasopharynx is more than 50%. Social damage due to this pathology is exacerbated by the tendency to its chronicity. -
Brucellosis (synonyms: Maltese fever, Bangui's disease) is a disease caused by various types of brucella, prone to chronic course, characterized by damage to the musculoskeletal system, nervous, reproductive and other systems. Chronic brucellosis (BC) is a zoonotic infectious-allergic disease that causes caused by bacteria of the genus Brucella, which lasts more than six months, is characterized by a pronounced polymorphism of clinical manifestations with a predominant lesion of the musculoskeletal, nervous, genitourinary, and other systems, with a tendency to recurrent course. The share of children under the age of 14 in the total incidence of "newly diagnosed" CD increased almost 3 times - from 5 to 15%, which is an indicator of the tense epidemiological situation for this infection. Group diseases of people with the number of cases of 10 or more cases are periodically recorded [10]. -
Role of beam diagnostic methods at pathological changes of the hip joint before endoprosthesis replacementEndoprosthesis replacement - operational treatment of diseases and damages of hip joint. The problem of prevention of complications and their negative effects is extremely actual [1] today. However the role of different beam techniques in identification of adverse effects and complications of endoprosthesis replacement of joints is studied insufficiently. Results of clinic and diagnostic and beam researches of 40 patients with pathology of hip joint arc analyzed. The used beam methods of research - roentgenography, multispiral computer tomography. At presurgical stage the main objective was detection of pathology of joint, definition of indications and planning of operative measure. Situation and relationship of components of endoprosthesis, condition of bone tissue, and also bone cement round cup and leg of prosthesis were key parameters of radiological assessment of outcomes of endoprosthesis replacement. Complex use of radiological techniques (roentgenography and spiral computer tomography) allows to specify and add semiotics of changes of bone tissue at the level of acetabular hollow and proximal department of femur after endoprosthesis replacement.
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The short-time results of early rehabilitation after tetralogy of fallot repair with functioning subclavian-pulmonary artery anastomosisThe paper presents the experience and results of early rehabilitation after subclavian-pulmonary artery anastomosis and tetralogy of Fallot repairs performed in RSCS named after acad. V.Vakhidov over a period of 40 years. The efficiency of regulated anastomosis application after Blalock-Taussig shunting was proved and the intensive care tactic in early postoperative period was optimized.
Journal problems of biology and medicine -
Prevalence of postmenopausal osteoporosis in bukhara regionQuestioning for 378 women from 50 to 80 years of age who are in menopause and live in Bukhara re-gion. The prevalence of osteoporosis among surveyed postmenopausal women living in Bukhara region com-prised 24.1%, osteopenia - 33.6%.With increase of age there the number of women with normal BMD signifi- cantly declines (from 50.5% at age of 50-59 to 5,0% - at ≥70).Dairy products were regularly consumed by less than half of the women (43.7%) and 46.3% were physically active during at least 30 minutes daily. Early men-opause was significantly more common among women with osteoporosis (39.6%), than in women with nBMD (20.6%). Irregular consumption of dairy products, low physical activity and the duration of menopause were the risk factors in the studied group of women
Journal problems of biology and medicine -
Medical and surgical activities carried out in simultaneous pathology (combination of gynecological and surgical pathology) in womenNumerous studies in recent years indicate not only the wide dissemination of simultaneous abdominal diseases, but unsatisfactory results of treatment of these diseases. In addition, a one-time surgical treatment of patients with two or three abdominal diseases is complex and not completely solved the problem.
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Frequency of occurrence small anomalies of development in children in the region PriaralyaWe examined 988 children aged from 3 till 6 years living in the Khorezm area and control group of 150 children of of Tashkent. The following methods were applied to inspection of children: kliniko-anamnesticheskiya, according to the analysis of fizikalny survey and primary medical documentation, and also instumentalny methods of research. By results of our research small anomalies of development and congenital defects of bodies and systems vyyavlit at children in ecologically unsuccessful regions by 3 times more often than at their contemporaries in ecologically safe region, a thorax and a backbone (50,3%) are characterized by the high frequency of combinations various the fenotipicheskikh and congenital morphogenetic options of development of skin (96,2%), the sky (81,6%), extremities and joints (77,5%).
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The role of trace elements in the development of thyroid diseaseThe study of trace element status in diffuse toxic goiter appropriate, depending on the functional activity of the thyroid gland. Investigated a number of elements that are "goitrogenic" or "strumogen" factors - the essential trace elements such as selenium, cobalt, copper, manganese and others. The study included 51 pa-tients with diffuse toxic goiter. The survey included: general clinical research study of thyroid status, study trace element status (determination of the content in the hair of patients with iron, selenium, manganese, co-balt, copper, zinc). The studies revealed deficiency of trace elements (iron, manganese, cobalt, copper, zinc) in diffuse toxic goiter, as well as the ability of hair to reflect long-term trends in trace element status of the body allow us to consider the above micronutrient deficiency as a risk factor for diffuse toxic goiter.
Journal problems of biology and medicine
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