The article describes the results of an experiment on the scientific topic 2P / 21 during the outbreak of theileriosis of cattle in Akmola region in June-August 2021. Using the methods of epizootological, clinical and microscopic studies, 43 individuals of young Aberdino-Angus and Kazakh white-headed breeds under the age of two years spontaneously ill with theileriosis were isolated, of which two groups were formed: an experimental group of 22 and a control group of 21 heads. The animals of the experimental group were treated according to the developed scheme with the use of specific (buparvaquone and oxytetracycline) and nonspecific drugs. The cattle of the control group were treated according to the previously proposed method using butalex and avicyclin.