Features Of The Clinical And Laboratory Course Of Tuberculosis Lymphadenopathy In Patients Without And With HIV Infection

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Mirazim Alimovich Khakimov , ., & Zarifa Abduraubovna Muminova , . (2021). Features Of The Clinical And Laboratory Course Of Tuberculosis Lymphadenopathy In Patients Without And With HIV Infection. The American Journal of Medical Sciences and Pharmaceutical Research, 3(09), 90–95. https://doi.org/10.37547/TAJMSPR/Volume03Issue09-15
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Abstract

Tuberculous lymphadenopathy without HIV infection, in comparison with those with HIV infection, was characterized by a more favorable clinical course, limited lesion and, especially important, limited caseous-necrotic changes. Analysis of the histological picture of the removed lymph nodes in patients with HIV-i made it possible to distinguish three activities of tuberculous lymphadenopathy: an inactive phase (with a predominance of a productive cellular reaction) - in 3 patients (5.3%), an active (with a predominantly productive-necrotic tissue reaction) - in 11 patients (19.3%), the phase of progression of the pathological process (mainly necrotic lesions, suppuration and formation of fistulas) - in 43 patients (75.4%). It was found that the inactive phase is 5.5 times more common in patients without HIV than in patients with HIV (29.3% and 5.3%, respectively, P˂0.001), while the active phase and the progression phase was 1.5 and 1.3 times more frequent in patients with HIV than in patients without HIV (19.3% and 13.1, respectively, P˃0.5; 75.4% and 57, 6%, respectively, P˂0.02).

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