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IMPROVING APPROACHES TO DIAGNOSIS, THERAPY, AND
PROGNOSIS OF TRIGEMINAL NEURALGIA
Mukhamadieva Ferangiz Shukhratovna
Bukhara State Medical Institute
https://orcid.org/0009-0005-9722-4215
https://doi.org/10.5281/zenodo.15804711
The Thesis
Objective:
To increase the effectiveness of classical trigeminal neuralgia
therapy by introducing pathogenetically oriented methods of relapse prevention
that take into account the influence of environmental factors.
Abstract:
The paper examines modern approaches to the treatment of
classical trigeminal neuralgia with an emphasis on the prevention of recurrence.
Attention is paid to the influence of environmental and meteorological factors on
the frequency and severity of exacerbations of the disease. The use of
pathogenetically directed methods of prevention, taking into account the
individual characteristics of the patient, helps to reduce the frequency of
relapses and improve the quality of life. The development of adapted therapy
regimens will improve the effectiveness of medical care.
Key words:
trigeminal neuralgia, treatment, prevention of relapses,
environmental factors, pathogenesis.
Research methods:
Clinical and neurological examination of patients with
classical trigeminal neuralgia. Magnetic resonance imaging (MRI) and
neuroimaging to assess structural changes. Collection and analysis of data on the
effects of environmental factors (temperature, humidity, atmospheric pressure).
Evaluation of the effectiveness of therapeutic protocols, including
pathogenetically based preventive measures. Statistical analysis to identify
correlations between environmental factors and relapse rates
Results:
A significant relationship was found between changes in
meteorological effects and exacerbations of trigeminal neuralgia. The use of
pathogenetically directed methods of prevention (including adaptation to
environmental conditions) reduced the recurrence rate by 30-40%. The
individualization of treatment regimens, taking into account environmental
factors, helped to improve the general condition of patients and reduce the
severity of pain syndrome. The results confirmed the need for an integrated
approach in diagnosis and therapy to improve the effectiveness of treatment.
Conclusion:
The improvement of the treatment of classical trigeminal
neuralgia is possible through the integration of pathogenetically based
THEORETICAL ASPECTS IN THE FORMATION OF
PEDAGOGICAL SCIENCES
International scientific-online conference
40
preventive methods, taking into account the effects of environmental factors. An
individual approach to treatment and prevention of relapses helps to reduce the
frequency of exacerbations, reduce pain and improve the quality of life of
patients. The data obtained substantiate the need to introduce environmental
monitoring into clinical practice in the management of this category of patients.
References:
1. AngioScan-01P, AngioScan-01M Devices for personal diagnostics of the
cardiovascular system: user manual / AngioScan-Electronics LLC. Moscow:
AngioScan-Electronics, 2011. 66 p.
2. Balyazin, V.A. Ways to reduce complications and relapses after microvascular
decompression in patients with trigeminal neuralgia / V.A. Balyazin, E.V.
Balyazina // Journal. Vopr. neuro. im. N.N. Burdenko. - 2003. - № 2. - pp. 6-9.
3. Balyazina, E.V. Anatomical prerequisites for the emergence of classical
trigeminal neuralgia / E.V. Balyazina // Collection of scientific papers dedicated
to the 80th anniversary of the neurological service in Ryazan. Ryazan, 2010. pp.
13-17.
4. Balyazina, E.V. Classical trigeminal neuralgia / E.V. Balyazina. Novocherkassk:
Lik, 2015. 278 p
5. Balyazina, E.V. Features of neurovascular conflict predisposing to the
development of neuralgic status // Proceedings of the X All-Russian Congress of
Neurologists. - N. Novgorod, 2012. - pp. 601-602.
6. Balyazina, E.V. Method of treatment of trigeminal neuralgia: Pat. 2612936
Russian. Federation / E.V. Balyazina, T.A. Isakhanova; published on 13.03.2017;
announced on 19.11.2015; No. 2015149838; Byul. Inventions. Useful models No.
8. 2017. 6 p
7. Balyazina, E.V. Topographic anatomical relationships of the trigeminal nerve
trunk with the superior cerebellar artery in patients with trigeminal neuralgia /
E.V. Balyazina // Morphology. - 2009. - No. 5. - pp. 27-31.
8. Grigoryan, Yu.A. Trigeminal neuralgia and tumors of the bridge-cerebellar
angle / Yu.A. Grigoryan, A.R. Sitnikov // Russian Neurosurgical Journal named
after Professor A.L. Polenov. - 2010. - Vol. 2, No. 1. -pp. 28-41.
9. Dymova, N.V. Immune disorders and endothelial dysfunction in the
hypertensive variant of chronic glomerulonephritis and their dynamics against
the background of therapy: Dissertation of the Candidate of Medical Sciences /
N.V. Dymova. - Kursk, 2007. - 176 p.
10. Kalakutsky, L.I. Measuring transducer of arterial pulsations for vascular
reactivity assessment systems / L.I. Kalakutsky, P.A. Lebedev, A.P. Gorlov //
Actual problems of radio electronics. Samara, 2003. pp. 105-107.
THEORETICAL ASPECTS IN THE FORMATION OF
PEDAGOGICAL SCIENCES
International scientific-online conference
41
11. Karnilova, L.E. The effect of intraosseous blockades on pain syndrome,
memory and cognitive evoked potential of P300 in a patient with exacerbation
of trigeminal neuralgia / L.E. Karnilova, E.L. Sokov, M.S. Nurmagamedova // The
Russian Journal of Pain. - 2014. - Vol. 42, No. 1. - pp. 110-111.
12. Konovalov, A.N. Microvascular decompression of the trigeminal nerve root in
the treatment of trigeminal neuralgia: Proceedings of the 14th Russian scientific
and practical conference "Neuropathic pain" / A.N. Konovalov, O.R. Orlova, U.B.
Makhmudov et al. // Vertebroneurology. - 2008. - Vol. 15, No. 1/2. - pp. 81-82.
13. Kurapova, M.V. Clinical and diagnostic significance of endothelial dysfunction
in patients with chronic kidney disease: Dissertation of the Candidate of Medical
Sciences / M.V. Kurapova. Samara, 2015. 145 p.
14. Milyagin, V.A. Modern methods for determining vascular stiffness / V.A.
Milyagin, V.B. Komissarov // Arterial hypertension. - 2010. - Vol. 16, No. 2. - pp.
137-138.
15. Ottewa, E.N. Arterial rigidity is a marker of the development of
cardiovascular diseases / E.N. Ottewa, E.V. Klinkova, O.G. Garbuzova et al. //
Clinical medicine. - 2012. - Vol. 90, No. 1. - pp. 4-12.
16. Rogozina, L.A. Endothelial dysfunction in patients with allogeneic renal
transplant / L.A. Rogozina, I.L. Davydkin, E.N. Iskhakov // Proceedings of the
Samara Scientific Center of the Russian Academy of Sciences. - 2014. - Vol.16, No.
5(4). - pp. 1305-1308.
