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DEVELOPMENT OF ANTI-TONZILITIC AND ANTI-MOLCHE TECHNOLOGY
Turayeva S.S.
1
Sayfullayeva X.A.
2
1
Samarkand city Instructor of the Department of
Preclinical Sciences at Zarmed University
2
Samarkand city Student of group 103 of the Faculty of
Pharmacy, Zarmed University
https://doi.org/10.5281/zenodo.15174663
Abstract
. As a result of the research, the composition of a caramel paste against tonsillitis
and expectoration based on a decoction of walnuts and pomegranate peel was developed. At
the same time, a method for preparing the caramel mass, adding it to the medicinal product,
and a technological scheme for the pastille were proposed.
Keywords.
Pastila, walnuts, pomegranate peel, decoction, tannin, tannins.
Introduction.
A complication of diseases of the upper respiratory tract, such as
bacteriological and viral inflammation of the throat, tonsillitis, pharyngitis, influenza (acute
respiratory infections), allergic cough, is a chronic cough with severe pain, which is now
widespread among the population.
According to statistics from the World Health Organization (WHO), tonsillitis,
inflammation of the throat, affects 10-15% of the world's population, including 20-25% of
young children. Due to insufficient attention to this disease, in 99% of developing countries,
deaths from acute inflammation of the upper respiratory tract affecting the lower respiratory
tract are observed in children under 5 years of age [1].
Currently, the use of plant raw materials in the production of medicines is common as an
alternative to synthetic drugs. The pharmacological effect of preparations based on plant
materials is not inferior to synthetic drugs, and their side effects are relatively insignificant.
Today, 112 species of medicinal plants grow in Uzbekistan, of which 70 are used in the
pharmaceutical industry [2].
The medicinal form of Pastilla has been used to treat throat infections since ancient times
(1000 BC). The earliest version of this remedy was made in Egypt using various products such
as honey, medicinal herbs, citrus fruits, and spices. These pastilles were modified by the Smith
Brothers in 1852 and by Luden in 1879. To increase the effectiveness of the pastilles, a small
amount of heroin and morphine was added to their composition [3].
Materials and methods of research.
To obtain a decoction of pomegranate peel and
walnut leaves in a 1:10 ratio, the AU-3 (Russia) infusion apparatus was used. Electronic scales
VK-300.1 were used to determine the average weight of the pastila. The tannin content of the
pastilles was determined by permanganatometry, and the moisture content of the finished
product was determined on the "MB35" Ohaus Corp. equipment from China.
Results.
The initial stage of the research began with the preparation of pomegranate peel
(Punica Granatum L.) raw materials. This variety was chosen due to the high content of tannin
in the hard-shelled "tuya tish" variety of pomegranate with a sour taste. After separating the
bark of both plants and drying at room temperature, a decoction was prepared in an infusion
apparatus in a 1:10 ratio. Caramel pastries were prepared based on the decoction. To prevent
the viscosity of the sugar syrup from increasing, apple cider vinegar was added to its
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composition. Our caramel paste was prepared by pouring into molds. The molds were cleaned
and lubricated with vegetable oil for better separation of the pastilles from the mold.
Conclusion.
As a result of the research, the optimal composition of a caramel paste from
a decoction of pomegranate peel and walnuts was selected, and a technology was developed.
The quality of the resulting paste was evaluated.
Foydalanilgan adabiyotlar/Используемая литература/References:
1.
Iskandarova Sh.F, Zohidova N.F. Oddiy anor (Punica granatum L.) po’stlog’i asosida
yo’talga qarshi karamelli pastilka tarkibini va texnologiyasini ishlab chiqish. Farmatsiya va
farmakologiya №1 (7) - 2024
2.
S. M. Aliqulov, I. M. Rasulov, F. X. Abdullaev, X. Yu. Nazarmetov. Dorivor oʻsimliklar
xalqimizning tabiiy boyligidir. Multidisciplinary Scientific Journal. Volume 3 | Issue 5 | 2022
984- 990 b.
3.
R. Axmedova Sredstva vozdeystviya na tannin v granatovom soke i kojure. Pishevaya
promishlennost\\ 2\\ 2016. – S. 36-38
.
