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Ветеринарно-санитарный контроль продуктов убоя крупного рогатого скота при болезнях лёгких и печени незаразной этиологии
целей исключительно безопасного в санитарном отношении продукта [1, 2]. Организация производственного ветеринарно-санитарного контроля при переработке больных животных должна исключить выпуск некачественных и небезопасных в ветеринарно-санитарном отношении мяса и субпродуктов. В результате исследований установлено, что говядина, полученная при убое больного бронхопневмонией и гепатозом молодняка крупного рогатого скота, по сравнению с мясом контрольных животных, имеет пониженные товарные качества.
Ветеринария илм-фанининг истиқболлари ва соҳани ривожлантиришдаги муҳим вазифалар
Анатомия и хирургия грудного лимфатического протока
АКЦИЯЛАР БОЗОРИДАГИ МУАММОЛАР ВА УЛАРНИ БАРТАРАФ ЭТИШ ЙЎЛЛАРИ
иқтисодиётни молиялаштиришда муҳимлиги айни ҳақиқат. Лекин мамлакатимизда бу
имкониятдан етарлича фойдаланилмаётганлигини ҳам шу ўринда алоҳида
таъкидлашимиз лозим. Қуйида айнан корпоратив қимматли қоғозлар бозори, хусусан
акциялар бозорини ривожлантиришга тўсқинлик қилаётган омиллар ва уларни
бартараф этиш масалаларига тўхталиб ўтамиз. Мамлакатимизда корпоратив қимматли
қоғозлар бозорини, умуман қимматли қоғозлар бозорини ривожлантириш учун молия
тизимида корпоратив молиянинг бирламчи аҳамият касб этишини таъминлашимиз
лозим.
Zootechnical indicators of agricultural poultry using anti-stress additive
Zoobiocenosis, insect, zoophile, drug, karatin, disinfestation, fly control, animal husbandry
Zashchitim scot ot teylorioza
Young animals in the aral sea regions the course of colibacteriosis and salmonellosis
Work is underway to further develop livestock farming in the country based on the development strategy of the new Uzbekistan
Ways to prevent fish bronchiomycosis and factors that cause it
Ways to determine the freshness of meat in the markets
products, sampling rules, preparation of extracts, techniques for determining the concentration (pH) of hydrogen ions.
Ways and methods of radiation impact reduction use of milk and meat
Water pathogens present in the wastewater flow of a large dairy in the summer and winter
Violation of protein- carbohydrate- lipid exchange, and dystrophy of a liver at cows
The actuality and necessity of the theme of the dissertation. Now in many countries of the world in livestock production the illness rate of productive cows’ violations of metabolism and diseases of a liver reaches up to 40-50 percent. The successful solution of these problems is important in case of the most complete satisfaction of requirement of the population of the country to animal products and ensuring food security.
Thanks to the undertaken agrarian reforms and basic changes in republic animal husbandry production the quantity of animals increases from year to year and considerably their productivity increases. The large-scale measures directed to prevention and elimination of diseases of animals including the measures directed to development and enhancement of methods of early diagnostics, successful therapy and prevention of a metabolic disorder and diseases of a liver at productive cows arc in this case carried out.
In recent years in the world in different geoecological conditions at productive cows depending on age, the periods of a lactation and pregnancy, and also diet types, pathology of metabolic disorders and dystrophy of a liver began to be shown in different forms and currents that dictates enhancement of traditional methods of diagnostics and trcatmcnt-and-prophylactic measures as obsolete and incapable to struggle against pathological conditions of difficult nature as the mixed pathology of a metabolic disorder with liver dystrophy. Proceeding from it, the researches directed to creation of a cartogram of level of proteinaceous, carbohydrate and lipid exchange at productive cows depending on their age, the periods of a lactation and pregnancy, types of a diet and geoecological conditions, scientific reasons for an etiology of metabolic disorders and dystrophy of a liver, studying of etiopatogcnctic communication of violations of that and other type of exchange with functions of a liver, development of methods of early diagnostics, group prevention and etiopatogcnctic therapy of violation of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver as the prevailing pathology in violation of exchange at productive cows, today, arc urgent.
This dissertation research to some extent serves accomplishment of the tasks provided in implementation planned by the Law of the Republic of Uzbekistan "On veterinary" and Resolutions of the President of the Republic of Uzbekistan of ПП-842 of April 21, 2008 "About additional measures for strengthening of stimulation of increase in a livestock of the cattle in personal subsidiary, Dchkan both farms and to expansion of production of animal husbandry products" and ПП-2460 of December 29, 2015 "About Measures for Further Reforming and Development of Agricultural Industry for 2016-2020", and also other standard legal documents accepted in this sphere.
The purpose of the study is development of methods of early diagnostics, etiopathogcnetic therapy and group prevention of violation of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver at cows depending on age, the periods of a lactation and type of a diet in different geoecological conditions of Uzbekistan.
Scientific novelty of the research is as follows:
for the first time in three geoecological (rather adequate, extreme and sharp and extreme) conditions of the republic the cartograms of level of protein, carbohydrate and lipid metabolism at heifers and cows is determined;
the etiopathogcnetic communication of disturbance of proteinaceous and carbohydrate and lipid exchange with a liver dystrophyarc and the etiology at cows is defined;
the technique of early diagnostics of disturbance of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver at cows based on the principles of medical examination special the hephatoclinical and the hcphatobiochimical tests is developed;
proteinaceous and vitamin and mineral feed additive “Ultrakctost”, the fabric medicine "Gcpastimulin" and germinal extract “Fekhoselcn” as highly effective trcatmcnt-and-prophylactic means at violation of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver at the cows consisting of local means the environmentally friendly, easily produced and cheap means arc developed and the order and conditions of their application arc made;
the technique of group prophylaxis of disturbance of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver at cows based on use of proteinaceous and vitamin and mineral additive “Ultrakctost”, the fabric drug "Gcpastimulin", germinal extract "Fckhoselen" and Trivit in the recommended doses and orders is developed;
the technique of treatment hypo - and atony of prcstomachs, a nutritional dystrophy, a ketosis, a nutritional osteodystrophy and a hepatodystrophy as typical illnesses of disturbance of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver at cows is improved.
CONCLUSIONS
1. Among cows of farms Samarkand (adequate), Kashkadarya (extreme) and Bukhara (it is sharp - extreme) the areas of the Republic of Uzbekistan violations of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver from which economic damage was averaged by 1,7-1,9 million sum on each head of cows in a year arc widely widespread.
2. Level of proteinaceous exchange at productive cows of increase in age, strengthening of a lactation and increase in degree of salinity of the soil goes down that in adequate conditions covers 60-90%, in extreme and sharp and extreme conditions-80-100%, including, strong lowering covers 10-20 and 10-40% of animals, respectively.
3. Level of carbohydrate exchange at productive cows of increase in age, strengthening of a lactation and increase in degree of salinity of the soil goes down that in adequate conditions covers 30-100%, in extreme and sharp and extreme conditions-60-100%, including, strong lowering covers 10-50 and 10-80% of animals, respectively.
4. At productive cows lipid exchange is exposed to peculiar changes depending on age, the periods of a lactation and pregnancy of animals, so quantity of general lipids, NEFA and general cholesterol on age of cows and strengthening of a lactation dynamically increased (to 522,4±20,55 mg of %, 13,6±0,91 mg of % and 3,4±0,10 mmol/1, respectively), amount of phospholipids, triglycerides, beta lipoproteids and air of cholesterol, generally went down (to 234,5±5,60 mg of %, 86,6±0,77 mg of %, 328,5±6,26 mg of % and l,30±0,05 mmol/1, respectively).
5. Disturbances of protein, carbohydrate and lipid metabolism at productive cows with rising of age, intensifying of a lactation and augmentation of degree of salinity of the soil (in the conditions of hay concentrated feeding, is even stronger) arc exposed to an excavation and pass a dystrophy of a liver which infectiousness in adequate conditions reaches to 31,5 - 38,0, in extreme to 33,3 - 44,0 and into sharp and extreme - to 36,0 - 48,0%.
6. At disturbance of proteinaceous and carbohydrate and lipid exchange and a dystrophy of a liver at cows special hcpatoclinical signs, characterized by tachycardia, a dyspnea, hypo and an atony of prestomachs, a licking disease, yellowness of visible mucosas, augmentation of border and morbidity of area of a liver and also the special hcpatobiochimical changes which arc characterized by decrease in a blood of quantity of hemoglobin, the total protein, albumins, urea, glucoses, Aethers of cholesterol, triglycerides, phospholipids, beta lipoproteins and activities of HE, augmentation of quantity of the general bilirubin, ketone bodies, NEFA, the general cholesterol and rising of activities the AsAT, the A1AT, LDG, SDG and GGT.
7. Neediness of a ration on Saccharum (for 40,7-53,2%), to Carotinum (for 48,6-60%) and to phosphorus (for 20-28,6%), excess of a calcium (for 30-66,8%), low Saccharum -protein (0,42-0,50) and high calcium and phosphorus the relations (2,33-3,33) in it arc the main reasons for disturbance of proteinaceous and carbohydrate and lipid exchange and a dystrophy of a liver at cows, and age (a biological factor), the lactation height period (an operational factor) and salinity of the soil (a geoecological factor) arc the contributing factors of this pathology.
8. Again developed means as proteinaceous and vitamin and mineral top dressing "Ultrakctost", the fabric medicine "Gcpastimulin" and rudimentary extract "Fckhoselen" in case of complex application in certain doses and conditions render on an organism of cows the vicar, adsorbent, laxative, haemo poetic, antioxidatic, anti-toxic, antioxidant, hepatogenous, estrogenic, and also nonspecific stimulating action, within 50-60 days promote improvement of the clinical status and digestion, normalization of proteinaceous, carbohydrate and lipid exchange, stimulation of a hemapoiesis, strengthening bile formed and bile excretory, detoxicational, albumin-synthesizing, glycogen-synthesizing, urea formed, bilirubin-conjugating, lipid-synthesizing and the lipid - oxidizing functionsof the liver, there by brakes dystrophic processions in it, recovers the immune status of an organism and will give the chance of increase the average live mass of cows for 15-15,5%, dairy productivity for 7-7,1%, to fertility for 8-10%, the average live mass of calfs in case of the birth for 8-8,4% and a decrease of degree of contamination of a liver dystrophy for 10-11%. Cost efficiency on each head of cows in a year averages 410000-410800 sum.
9. In case of treatment of the diseases developing against the background of violation of proteinaceous and carbohydrate and lipid exchange and dystrophy of a liver, application of an advanced method of etiotrophieal therapy of the based on use in the established doses and combinations of proteinaceous and vitamin and mineral additive "Ultrakctost", fabric medicine "Gcpastimulin" and rudimentary extract "Fckhoselen" in combination with traditional methods of treatment gives the chance to reduce treatment term by 2-6 days, to prevent danger of a forced face for 33,3%, to thereby gain economic effect counting on one head of a cow from 21200 to 1 million 65760 sum.
10. To realize early diagnostics of disturbance of proteinaceous and carbohydrate and lipid exchange and a dystrophy of a liver in respect of medical examination and at the same time to conduct the planned clinical trials referred on identification special the hcpatoclinical of the signs consisting of a licking disease hypo - and atony of prestomachs, accelerations of pulse and respiration, yellowness of mucosas, morbidities in a liver and augmentation of its border, developing on the basis of the general metabolic syndrome and the planned laboratory researches referred on identification special the hcpatobiochimical of the changes indicating (oligacmy, hypoprotcinacmy, hypoalbuminacmy, hypoglucacmy, hypouraraemy, a blood of quantity decrease in of Aethers of a cholesterol, triglycerides, phospholipids beta lipoproteins, activity of HE and augmentation of gammaglobulins, general bilirubin, not esterified fatty acids, general cholesterol and rising of activities A1AT, AsAT, SDG, LDG and GGT).
11. For prophylaxis of disturbance of proteinaceous and carbohydrate and lipid exchange and a dystrophy of a liver 60-day group preventive therapy based on use since third month of a lactation is recommended, to cows, in addition to the main ration, to give daily in an admixture with compound feed in a dose of 0,5 g/kg proteinaceous and vitamin and mineral additive "Ultrakctost", every other day (after each 10 injections 20 daily break) subcutaneously in a dose of 5 ml / 100 to kg of the fabric drug "Gcpastimulin", inside daily (after each 10 receptions a 20-day break) in a dose of 0,5 ml/kg of rudimentary extract "Fckhoselen" and intramuscularly weekly in a dose of 10 ml of Trivit.
12. For treatment of illnesses of the cows developing on the basis of disturbance of proteinaccousand carbohydrate and lipid exchange and a dystrophy of a liver as Also an atony of prestomachs, the Nutritional dystrophy, the Ketosis, the Nutritional osteodystrophy and Hcpatodystrophy, is recommended the method of advanced etiopatogcnctic therapy based on use in addition to traditional methods and agents daily in an admixture with compound feed in proteinaceous and vitamin and mineral additive "Ultrakctost", fabric drug "Gcpastimulin" and rudimentary extract "Fckhoselen" in definite dosis and in definite conditions.