JOURNAL OF IQRO – ЖУРНАЛ ИҚРО – IQRO JURNALI – volume 15, issue 02, 2025
ISSN: 2181-4341, IMPACT FACTOR ( RESEARCH BIB ) – 7,245, SJIF – 5,431
ILMIY METODIK JURNAL
Azimova Gulnoza Ravshanovna
Senior Lecturer, PhD, Department of General Surgery, FMIOPH, Fergana, Uzbekistan
ravshanovnagulnoza@gmail.com
Ismailov Davlatbek Dilshod ugli
Valijonov Burkhoniddin Jasurovich
Resident, Department of General Surgery, FMIOPH, Fergana, Uzbekistan
burkhon.valizhonov@gmail.com
MORPHOLOGICAL BASIS OF PRACTICAL RECOMMENDATIONS ON
CONFOCAL MORPHOMETRIC INDICATORS OF TAILBONE INJURY
Abstract:
Modern confocal multiplex morphometry was used to morphometrically substantiate
the specificity of changes in bone tissue in digital imaging of tailbone injuries. To establish age-
related changes in tailbone injuries, pre-prepared microsamples were scanned, measured at
appropriate points, and analyzed. According to the analysis results, the highest indicator of
reparative regeneration following tailbone injury was observed at ages 34-48 years. In older
adults, these indicators confirmed the intensification of osteoporosis as a result of destructive and
degenerative changes in bone tissue.
Keywords
: tailbone, osteoporosis, confocal morphometry.
Introduction
Confocal morphometry, while not explicitly detailed in the provided contexts, can be inferred to
utilize various morphological indicators to assess the severity of tailbone injuries, drawing
parallels from the methodologies used in vertebral and other bone injury assessments.
Morphometric quantitative approaches, such as those used in vertebral fracture assessments,
involve measuring vertebral div heights and can be adapted for tailbone injuries to evaluate
changes in bone structure and alignment[1]. The classification of endplate injuries into mild,
moderate, and severe categories based on morphological characteristics, such as fissure-type and
irregular depression-type injuries, provides a framework that could be applied to tailbone injuries
to predict long-term outcomes like disc degeneration and loss of intervertebral height[2] [5].
Additionally, the study of trabecular bone damage intensity and its relationship with vertebral
creep rate suggests that similar morphometric measurements could be used to predict progressive
deformity in tailbone injuries[4]. The use of CT and MRI imaging to classify injury severity and
predict outcomes, as seen in thoracolumbar fractures, could also be relevant for tailbone injuries,
allowing for a detailed analysis of bone and soft tissue changes[6]. These methodologies
highlight the importance of detailed morphometric analysis in understanding the severity and
potential progression of tailbone injuries, providing a comprehensive approach to injury
assessment and management.
Relevance of the problem.
An increase in obesity rates among the world's population is
observed, with an average weight gain of 1.57-3.85 kg per year of age compared to the baseline
at age 1. Among the populations of the USA, European countries, and South America, the
average weight gain after the age of 40 is increasing by approximately 3.57 kg per year. This
indicates an average increase in div weight of 35 kg or more at ages 40-59. This figure was
found in 23% of women over 40 years of age on average in the USA, Europe, and South
America [1]. As a result, the development of osteochondrosis, osteoarthritis, and osteoporosis
occurs in the spine, consequently leading to the adoption of a sedentary lifestyle. Specifically, in
JOURNAL OF IQRO – ЖУРНАЛ ИҚРО – IQRO JURNALI – volume 15, issue 02, 2025
ISSN: 2181-4341, IMPACT FACTOR ( RESEARCH BIB ) – 7,245, SJIF – 5,431
ILMIY METODIK JURNAL
sedentary populations, injuries related to the coccyx account for 3.47% of all injuries, indicating
that an average of 25 million women aged 40-59 worldwide suffer from this condition. This, in
turn, further confirms the relevance of this problem. In the Russian Federation and CIS countries,
this indicator is most common among people aged 50-59, with an average annual weight gain of
2.27-5.55 kg. One of the main causes of obesity among women aged 50-59 in the population of
Uzbekistan is the cessation of sexual activity at an average age of 48-53 years. This decline in
sexual activity is characterized by changes in the endocrine system and the occurrence of
osteoporosis in a diffuse form. As a result, among the population of our country, the incidence of
diseases associated with the spine in women aged 48-59 years averages 42.85%, of which 5.8%
are diseases associated with the coccyx. This necessitates the immediate initiation of research on
this topic.
Discussion and results.
It was determined that the volumetric area of bone trabeculae relative to
the cavity in the coccygeal bone of 18-44 year-olds was 394.02 ±4.17 mm3. In the 2nd group,
consisting of 45-59 year-olds, the volumetric area of bone trabeculae relative to the cavity was
217.96 ±6.93 mm3, which is 1.8 times less than in the 1st group.
In the 3rd group, consisting of 60-74 year-olds, the volumetric area occupied by bone trabeculae
relative to the cancellous bone substance was 64.99±1.34 mm3 out of 13000 μm3, which is 4.9%.
This is 2.24 times less than in the 1st group and 1.6 times less than in the 2nd group. These
differences indicate that they are also similar in terms of differences in other parts, confirming
that most changes are age-related.
In the 4th group, at the age of 75-90 years, the volume of 13000 μm3 was 0.53±0.01 mm3, and
the average occupied area was 2.34%. It decreased by 6.1 times compared to the 1st group, by
3.35 times compared to the 2nd group, and by 2 times compared to the 3rd group.
In the 5th group, consisting of those 90 years and older, it decreased by 12 times compared to
the 1st group, by 8.5 times compared to the 2nd group, by 5.4 times compared to the 3rd group,
and by 2 times compared to the 4th group. Of course, these indicators, in their age-related
aspects, confirm the role of duration in coccygeal bone injuries.
Based on the results obtained, the following practical recommendations are suggested:
1. Considering that morphologically, muscle-vascular and nerve adhesions arising from
tailbone injuries cause pain syndrome, this information is used as a basis for recommending
palliative or radical corrective procedures to patients.
2.
Taking into account the active lifestyle of patients aged 18-44 years with tailbone injuries,
the highest probability of developing coccydynia is morphologically substantiated, which allows
for a prospective prediction of the onset of pain syndrome in these patients.
3.
In patients aged 75-90 and over 90 years, tailbone injuries are milder compared to those
aged 18-44 and 45-59 years, and the lack of necessity for surgical intervention is
morphologically justified, which forms the basis for prescribing conservative treatment.
4.
From a histochemical perspective, tailbone injuries in patients aged 60-74 years are
associated with a high probability of developing foci of pathological calcification. To prevent
urinary issues in the pelvic cavity and irritation of the large intestine, closed reduction is required.
Conclusion
1. Based on clinical and anamnestic data, it was found that destructive and degenerative changes
in the coccyx occurring within 3-9 months after acute injury were most prevalent in the age
groups of 45-59 and 60-74 years. Regarding gender-related aspects, the highest incidence was
JOURNAL OF IQRO – ЖУРНАЛ ИҚРО – IQRO JURNALI – volume 15, issue 02, 2025
ISSN: 2181-4341, IMPACT FACTOR ( RESEARCH BIB ) – 7,245, SJIF – 5,431
ILMIY METODIK JURNAL
observed in the female contingent aged 35-48 years, with a total of 81.6% of women and 18.4%
of men affected.
2. Concerning age-related pathomorphological changes of the coccyx, the process of reparative
regeneration prevails in individuals aged 18-44 years, while in those aged 45-59 years, it
continues with the development of resorption cavities. In the 60-74 age group, changes mainly
manifest as cystic dilation of the coccyx, destruction of bone trabeculae, fusion of lesions, and
the occurrence of osteoporosis.
3. Histochemical examination of the coccyx revealed age-related aspects, showing that the
formation of fuchsinophilic fibers was more pronounced in the 45-59 age group compared to
those aged 18-44 years. A sharp decrease in fuchsinophilic fibers in individuals aged 60-74 years
and older was found to predispose the coccyx to secondary injuries.
4. Regarding the age-related morphometric aspects of the coccyx, it was found that in 90-year-
olds, the thickness of the bone trabeculae in the cancellous substance of the coccyx was
30.01±1.79 μm, indicating osteoporosis. In comparison to coccyx injuries, it was determined that
the thickness decreased by 4.93 times compared to the 1st group, 4.4 times compared to the 2nd
group, 3.77 times compared to the 3rd group, and up to 2.7 times overall reduction in bone
trabeculae thickness was observed.
References:
1. Тўхтаев, Ж. Т., Ботиров, Н. Т., & Нишонов, Э. Х. (2023). Болдир-ошиқ бўғими
шикастланишларини ташхислаш ва даволаш. Zamonaviy tibbiyot jurnali (Журнал
современной медицины), 1(1), 27-39.
2. Мусаева,
Ю.
А.
(2025).
АЛКОГОЛЛИ
ПАНКРЕАТИТДА
ЛИМФА
ТУГУНЛАРИНИНГ ГИСТОКИМЁВИЙ ЎЗГАРИШЛАРИ. MODERN EDUCATIONAL
SYSTEM AND INNOVATIVE TEACHING SOLUTIONS, 1(7), 29-31.
3. Латибжонов, А., & Умарова, С. (2023). Технологии искусственного интеллекта в
медицине. in Library, 1(1).
4. Ёкубов, Д., & Мазалова, А. (2024). On differential diagnostics of spinal cord pathology of
organic and functional genesis. Актуальные вопросы фундаментальной медицины: сегодня и
в будущем, 1(1), 36-36.
5. Ёкубов, Д. (2025). Роль анатомических и гормональных факторов в патогенезе
варикоцеле у детей и методы его профилактики (обзор литературы). in Library, 1(1), 26-30.
6. Xamedxuja o‘g‘li, N. E. IMPROVEMENT OF TREATMENT METHODS FOR CALF-
ASIK JOINT INJURIES.
7. Xamedxuja o‘g‘li, N. E. (2023). Pathogenetic Mechanisms of the Development of Severe
Functional Disorders in Injuries of the Calf-Acorn Joint. SCIENTIFIC JOURNAL OF APPLIED
AND
MEDICAL
SCIENCES,
2(11),
427–429.
Retrieved
from
https://sciencebox.uz/index.php/amaltibbiyot/article/view/8628
8. Ravshan o'g'li, K. S., & Mavlonjon o’g’li, Q. J. (2024). Review Of The Use Of
Tomosynthesis For The Diagnosis Of Injuries And Diseases Of The Musculoskeletal
System. Frontiers in Health Informatics, 13(6).
9. Qoraboyev Jasurbek Mavlonjon O‘G‘Li, & Raximova Ruxshona Shavkat Qizi (2024).
KATTALARDAGI OG‘IR MIYA SHIKASTLANISHI. Eurasian Journal of Medical and
Natural Sciences, 4 (2), 156-162. doi: 10.5281/zenodo.10776140
10. Meliboev, R. A., & Eminov, R. I. (2025). EXPLORING METHODS TO IMPROVE THE
TREATMENT
OF
COMPLICATIONS
ARISING
FROM
ENDOUROLOGICAL
OPERATIONS FOR URINARY STONE DISEASE (LITERATURE REVIEW). mortality, 4, 13.
JOURNAL OF IQRO – ЖУРНАЛ ИҚРО – IQRO JURNALI – volume 15, issue 02, 2025
ISSN: 2181-4341, IMPACT FACTOR ( RESEARCH BIB ) – 7,245, SJIF – 5,431
ILMIY METODIK JURNAL
11. Karabaev Jasurbek Mavlyanjanovich. (2025). CURRENT CHALLENGES AND
ADVANCES IN PEDIATRIC TRAUMATOLOGY. International Multidisciplinary Journal for
Research
&
Development,
12(05),
157–160.
Retrieved
from
https://www.ijmrd.in/index.php/imjrd/article/view/3051
12.
Alpersovna, M. Y., & Erkinjon o‘g‘li, L. A. (2025). ALKOGOLLI PANKREATIT:
SABABLARI, BELGILARI VA DAVOLASH USULLARI. ZAMONAVIY TA'LIMDA FAN
VA INNOVATSION TADQIQOTLAR JURNALI, 3(2), 17-22.
