Volume 03 Issue 08-2023
15
American Journal Of Agriculture And Horticulture Innovations
(ISSN
–
2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.
471
)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
In this article, Rubia tinctoru L technology of obtaining a dry extract of a medicinal plant . Rubia tinctoru L the plant It
is used in medicine and folk economy and dyeing fabrics and materials natural chemicals extracted from plants as
paint their uses are highlighted.
KEYWORDS
Rubia tinctoru L , Rubia iberica, technology, alizarin, anthracene, ruberythric acid, galiosin, purpurin, xanthopurpurin,
pseudopurpurin, rubiadin-glucoside, munistin, lucidin, ibericin, urinary tract stone, kidney stone, gall bladder stone,
gout , cotton, fabric, natural dye.
INTRODUCTION
Research Article
PAINTER ROYAN TECHNOLOGY OF OBTAINING DRY EXTRACT OF
PLANT ROOTS
Submission Date:
August 20, 2023,
Accepted Date:
August 25, 2023,
Published Date:
August 30, 2023
Crossref doi:
https://doi.org/10.37547/ajahi/Volume03Issue08-04
Asishmuratova
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan
BT Ibragimov
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan
Astoraev
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan
Jmashurov
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan
TA Khajibaev
Institute Of Chemistry Of Plant Substances Named After Academician S. Yu. Yunusov Of The Faculty Of Arts Of
The Republic Of Uzbekistan, Uzbekistan
AX Islamov
Institute Of Bioorganic Chemistry Named After Academician Ossadikov Of The Uzrfa, Uzbekistan
Journal
Website:
https://theusajournals.
com/index.php/ajahi
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 03 Issue 08-2023
16
American Journal Of Agriculture And Horticulture Innovations
(ISSN
–
2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.
471
)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
Today's per day on a global scale extensive measures
are being taken to organize scientific research at a high
level in the direction of developing the creation of
effective drugs based on local raw materials and to
provide the national pharmaceutical market with
quality drugs. On the basis of the measures
implemented in this direction, a number of important
practical results are being achieved in terms of
organizing
the
development
of
competitive
preparations based on natural plant raw materials. As
it is known , studying the biology of Rubia tinctorum
plant species, which has been used by people for many
years, and preparing a cheap and high-quality medicine
that replaces imports by separating natural medicines
from local raw materials is the first step. creation of
material bases is of urgent importance. Such
preparations can be isolated from the medicinal plant
Rubia tinctorum and used in medical practice and folk
economy.
THEORETICAL PART
Dyed roan - Rubia tinctorum L. and Georgian roan
Rubia iberica C. Koch. (Rubia tinctorum L. var. Iberica
Fisch. ex DC) belongs to the Rubicaeae family. It is
found in Ukraine, Moldova, in the south and southeast
of the European part of Russia, in the Caucasus
(Azerbaijan, Georgia, Armenia, Dagestan) and Central
Asia. in Uzbekistan Basically ditch on the sides , bushes
_ between , channels along , in the fields and in the
gardens grows [1-4]
Colorful dream The species of the plant is a perennial
plant with a height of 30-150 cm. The rhizome is long,
creeping, branched, cylindrical, thick, jointed, multi-
headed. The stem is covered with several, four-
pointed, jointed, spiky and looped coarse hairs. The
leaf is oval-ovate, shiny, the veins on the lower side are
covered with coarse hairs with loops, and they are
arranged in bundles of 4-6 on the stem with a very
short band. The flowers are small, greenish-yellow in
color, gathered in a semi-umbrella growing from the
axils of the leaves, forming a bag-shaped inflorescence.
The calyx is not clearly known, the corolla is 5, united,
funnel-shaped, the paternity is 5, the maternal node is
2-digit, located below. The fruit is a 1-2-seeded,
spherical, first red, later turning black wet fruit. It
blooms in June-August, the fruit ripens in August-
September. Rubia tinctorum .
Volume 03 Issue 08-2023
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American Journal Of Agriculture And Horticulture Innovations
(ISSN
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2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
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(2021:
5.
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(2022:
5.
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)
(2023:
7.
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)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
Figure 1. Colorful dream Above ground and below (root) part of the plant
Colorful dream The finished product of the harvested plant consists of rhizomes and root pieces. The thickness of
rhizome pieces depends on the year they were dug up from the ground. One-year-olds are thin, two-year-olds are
thick, and they get thicker every year. The upper side is reddish brown. When it is cut crosswise, the bark layer is red-
brown, and the wood part is red. The product has a characteristic weak smell, sweeter at first, and then a slightly sour
and bitter taste. The rhizome turns the water brownish-red. The underground part (root) of the Rubia tinctorum plant
is shown to be thin in the first year and to grow in the second and third year (Fig. 2).
Figure 2. Colorful dream The root of the plant is thin in the first year and grows in the second and third year
Colorful dream the moisture content of the product
harvested from the plant is 13%, total ash is 10%, other
parts of the plant (stems, leaves, etc.) are 1.5%, organic
compounds are 1% and mineral compounds are more
than 1%, the content of the product the amount of
anthraglycosides (those united in the form of
glycosides) should not be less than 3% [5-7] .
rhizome of Rubia tinctorum contains up to 5-6%
anthracene compounds (alizarin, ruberythric acid,
galiosin, purpurin, xanthopurpurin, pseudopurpurin,
rubiadin-glucoside, munistin, lucidin, ibericin, etc.).
Anthracene Alizarin Ruberythric acid
Volume 03 Issue 08-2023
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American Journal Of Agriculture And Horticulture Innovations
(ISSN
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VOLUME
03
ISSUE
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Pages:
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(2022:
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OCLC
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Publisher:
Oscar Publishing Services
Servi
Purpurin Pseudopurpurin lucidin
In addition to anthracene products, organic acids in plant roots contain up to 15% sugars, proteins, pectin substances,
ascorbic acid , and citric, malic, and tartaric acids. occurs.
ascorbic acid citric acid malic acid tartaric acid
The root of Rubia tinctorum plant contains carbohydrates, phenolic acids and their derivatives, coumarin,
anthraquinone, triterpenoids, flavonoids (quercetin, kaempferol, apigenin).
antiroquinone quercetin kaempferol apigenin
Colorful dream In medicine, the plant has antispasmodic and diuretic effects, as well as softening of kidney stones
(phosphates). Therefore, medicinal preparations are used in ureteral stones, kidney stones, gall bladder stones and
gout . [5-7]
Colorful dream In addition to the medicinal use of the plant, dyeing with natural chemicals extracted from the royan
plant as a natural dye for dyeing threads, glam, fabrics, and materials grown in our Republic, which is mainly produced
from silk and cotton , leads to an increase in the number of jobs [ 5-7], (Fig. 3).
Volume 03 Issue 08-2023
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American Journal Of Agriculture And Horticulture Innovations
(ISSN
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2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
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FACTOR
(2021:
5.
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(2022:
5.
705
)
(2023:
7.
471
)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
Figure 3 . Colorful dream yarn dyed with natural chemicals extracted from plants
DISCUSSION OF RESULTS
Today's in the day a new product developed in the field
of pharmaceuticals and medicine through a scientific
approach based on natural medicinal plants in the
world if a bioactive additive (BFQ) is created and put
into production and jobs are created, the number of
unemployed is reduced and Satisfying the internal
demand of our republic and creating the opportunity
to export abroad according to many our scientists
scientific research are taking Colorful dream "ZPG 150"
that allows drying of 200 l of solution per hour in the
scientific and technological center adapted to GMP
conditions, launched in cooperation with the scientists
of the Institute of Bioorganic Chemistry named after
academician OSSadikov of the UzR FA . » (PRC)
experiments were carried out in the device that allows
extraction methods to be carried out in a spray drying
extractor as follows. Paint coating on the extraction
device plant 10.0 kg was crushed into 4-6 mm size and
100.0 l (hydromodule 1:10) of 80% etonol was poured ,
then water vapor was sent to the "steam jacket" of the
extractor and heated to a temperature of 60 C.
heated and left for 24 hours. The extract is drawn from
the lower part of the extractor by a specially installed
pump, driven in a specially equipped rotor equipment
with 80% ethanol , and dyed. Aqueous extract of the
plant was collected and poured. The extraction
process was carried out under the same conditions as
the first one. For this purpose, another 100.0 l
(hydromodule 1:10) of 80% etonol was prepared from
the extracted ethanol and drained from the upper part
of the extractor again by raining. extraction was
performed three times in this way. At the end of the
extraction process, the extract (60, l) was poured and
the results were analyzed (Table 1).
Table 1
Rubia tinctorum plant with 80% ethanol under 60 C temperature
Number
of extract
infusions
Raw material
weight kg
Extraction
time, hours
Raw
materials
and 80%
ethanol
80% ethanol extract
(ml)
Station %
1
10
24
1:10
100
-
2
again
24
1:10
100
-
3
again
24
1:10
100
total
10
24
1:10
300
16.9
Production and drying of Rubia tinctorum dry extract
technological general block sx was developed . Rubia
tinctorum plant is crushed in a mill (1) in size 4-6 mm,
weighed on a scale (2), placed in an extractor (5) in the
amount of 10 kg, and from a scale (3, 4) 100 l
(hydromodule 1:10) 80 % etonol was placed and stewed
for a day for 24 hours. In this method, the raw material
was extracted 3 times. The resulting 280 l extract was
filtered on a notch filter (8) and collected in a vessel (9)
and condensed in a vacuum evaporator (10) until 25 l,
Volume 03 Issue 08-2023
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American Journal Of Agriculture And Horticulture Innovations
(ISSN
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2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
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FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.
471
)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
i.e. 15% dry residue, and cooled (12). Then (13) was
poured into a vessel and spray-dried in an Anhydro No.
2 (Denmark) device . It was dried in a spray dryer with
hot air inlet at 170°C, outlet at 80°C, air pressure 0.2
MPa for 50 minutes (RS-12). The dry extract substance
(M-16) with a content of not less than 16-17% of the
obtained product was crushed and packaged as a
finished product. The technological process and device
scheme for extracting dry extract from the plant was
developed (Scheme 1).
Scheme 1
Technological scheme of the process of obtaining the substance " Rubia tinctorum ".
(1-mill, 2-weighing, 3,4- (60°C 80% etonol) tank, 5,6,7-extractor, refrigerator, trolley for shot, 8-filter, 9-container for
filtered extract, 10 -vacuum evaporator equipment, 11-container for extracted solvent, 12-(for settling) separation
funnel, 13-container, RS-12 spray dryer, M-16 grinder, 17- drying cabinet .
Colorful dream The appearance of the substance obtained by the extraction method of the plant root extract in 80%
ethanol in a spray drying extractor is presented in (Fig. 4).
Volume 03 Issue 08-2023
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American Journal Of Agriculture And Horticulture Innovations
(ISSN
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2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
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FACTOR
(2021:
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(2022:
5.
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)
(2023:
7.
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)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
Figure 4. Colorful dream the substance of the root of the plant and its extract in 80% ethanol.
Colorful dream The root extract of the plant in 80%
ethanol was extracted by spray drying extractor. In the
spray dryer, the inlet of the hot air stream was set to
170°С, and the outlet to 80°С. The amount of the
obtained product is not less than 16-17% dry extract
substance was crushed and packaged as a finished
product.
CONCLUSION
1. A painting The protective substance was extracted
by spraying the extract of the root of the plant in 80%
ethanol in an extractor , and it was determined that the
amount of the obtained product should not be less
than 16-17%.
2. Colorful dream When extracting the substance of
the root of the plant in the spray drying device , the
inlet of the hot air stream was set at an average of
170°C, and the outlet at 80°C.
REFERENCES
1.
Life is natural. V 6 t. T. 5. Ch. 2. Tsvetkovye rasteniya
/ P od ed. A. L. Takhtadzhyana . - M.:
Prosveshchenie, 1981. - S. 358.
2.
Botany. Encyclopedia "Vse rasteniya mira" / Per.
English (ed. Grigorev D. and Dr.) - Konemann , 2006
(Russian edition). -S . 802. - ISBN 3-8331-1621-8 .
3.
Pharmacognosy (H. Kholmatov, O'. Ahmedov) Abu
Ali ibn Sina Tashkent 1997.
4.
Kh.Kholmatov, O'.A.Ahmedov, Pharmacognosy:
textbook, Tashkent, NMB named after Ibn Sina,
1995.
5.
Islamov.
A.Kh.,
Ishmuratova.A.S.,
Gaybullaeva.O.O.,
Kadirova.Sh.O.
,Tashpulatov.F.N.,
Khudoynazarov.M.,
Abdug'aniev.A., G'aniev.Q. // Medicinal use of the
root of Rubia Tinctorum L and determination of
micro and macroelements // O' zMU modern status
and prospects of functional polymers science
professors
and
young
scientific-practical
conference of scientists materials (March 19-20,
2020) B.315-316
6.
Ishmuratova AS , Islamov AX , Abdimalikov II //
Ruby tintorum l plant mineral elements of the root
and in medicine application // ARES, Academic
Research In Educational Sciences Volume 3 . Issue
5 . 202 2 \ 05 . ISSN :2181-1385 . Gite - Factor : 0,89 /
SIS :1,12 SJIF 5,7 / UIF :6,1 DOL :10.24412/2181-1385-
2022-5-1214-1220
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Ishmuratova AS Islamov A.Kh. // DETERMINATION
OF THE TOXICITY OF RUBIA TINCTORUM L. ROOT
EXTRACT// Acad. S. Yu. Yunusova Institut khimii
rastitelnyx veshchestv AH RUz mejdunarodnaya
nauchno-teknicheskaya konferensiya Aktualnye
Volume 03 Issue 08-2023
22
American Journal Of Agriculture And Horticulture Innovations
(ISSN
–
2771-2559)
VOLUME
03
ISSUE
08
Pages:
15-22
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.
471
)
OCLC
–
1290679216
Publisher:
Oscar Publishing Services
Servi
problemy
khimii
prirodnyx
soedineniy
posvyashchaetsya
80-letiyu
akademii
nauk
respubliki uzbekistan 15-16 marta. Tashkent, 2023.-
P .-164.
