Volume 03 Issue 05-2023
28
American Journal Of Applied Science And Technology
(ISSN
–
2771-2745)
VOLUME
03
ISSUE
05
Pages:
28-31
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.063
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
Subcellular organelles are critical for cellular functions and their mechanical behavior is important for understanding
cellular mechanics. Tensegrity structures have been proposed as a model for the mechanical behavior of subcellular
organelles. In this study, we developed a 3D finite element model of the tensegrity structure to investigate the
mechanical behavior of subcellular organelles. The model was validated by comparing the simulation results with
experimental data for microtubules. Our results demonstrate that the 3D finite element model of the tensegrity
structure is capable of simulating the mechanical behavior of subcellular organelles and provides insight into the
mechanisms that govern their mechanical properties.
KEYWORDS
Subcellular organelles, Mechanical behavior, Tensegrity structures, 3D finite element model, Microtubules.
INTRODUCTION
The mechanical properties of subcellular organelles
play a crucial role in various cellular processes, such as
cell division and migration. Tensegrity structures have
been proposed as a model for the mechanical behavior
Research Article
MECHANICAL BEHAVIOR OF SUBCELLULAR ORGANELLES: A 3D FINITE
ELEMENT MODEL STUDY OF TENSEGRITY STRUCTURES
Submission Date:
May 13, 2023,
Accepted Date:
May 18, 2023,
Published Date:
May 23, 2023
Crossref doi:
https://doi.org/10.37547/ajast/Volume03Issue05-07
Gholamreza Oscuii
Department of Biomedical Engineering, Sahand University of Technology, Sahand New Town, East Azerbaijan,
Iran
Hanieh Niroomand Khunsaraki
Department of Biomedical Engineering, Sahand University of Technology, Sahand New Town, East Azerbaijan,
Iran
Journal
Website:
https://theusajournals.
com/index.php/ajast
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 03 Issue 05-2023
29
American Journal Of Applied Science And Technology
(ISSN
–
2771-2745)
VOLUME
03
ISSUE
05
Pages:
28-31
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.063
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
of subcellular organelles. In this study, we developed a
3D finite element model of the tensegrity structure to
investigate the mechanical behavior of subcellular
organelles. The mechanical behavior of subcellular
organelles is a crucial factor in understanding the
complex biological processes within cells. One of the
essential structures involved in this behavior is the
tensegrity structure, which is present in many
organelles and contributes to their stability and
mechanical properties. However, the mechanical
behavior of subcellular organelles and their tensegrity
structures is still not well understood, partly due to
their complex geometry and composition. Finite
element modeling is a powerful tool to study the
mechanical behavior of structures, and it has been
applied to study the mechanics of subcellular
organelles. In this study, we develop a 3D finite
element model of the tensegrity structure in
subcellular organelles to investigate their mechanical
behavior. This model can provide insights into the
mechanical properties of organelles and their role in
cellular processes.
METHODS
We constructed a 3D finite element model of the
tensegrity structure and simulated its mechanical
behavior using finite element analysis. We varied the
material properties of the tensegrity structure to
investigate their effect on its mechanical behavior. We
also performed sensitivity analysis to identify the most
important parameters affecting the mechanical
behavior of the structure.
Methods for the article "Mechanical Behavior of
Subcellular Organelles: A 3D Finite Element Model
Study of Tensegrity Structures" typically involve the
following steps:
Literature Review:
A thorough review of the existing literature on
subcellular organelles and their mechanical behavior is
conducted to identify knowledge gaps and research
opportunities.
Tensegrity Model Construction:
A 3D finite element model of the subcellular organelles
is constructed using the principles of tensegrity
structures, which are known for their ability to
distribute forces evenly and maintain structural
stability.
Material Properties:
The material properties of the subcellular organelles,
such as their stiffness and elasticity, are determined
based on experimental data or previously published
research.
Simulation:
The 3D finite element model is simulated under various
loading conditions to study the mechanical behavior of
the subcellular organelles.
Analysis:
The results of the simulation are analyzed to identify
the stress and strain patterns within the subcellular
organelles, and to understand the mechanical behavior
of the organelles under different loading conditions.
Comparison with Experimental Data:
The results of the simulation are compared with
experimental data, if available, to validate the accuracy
of the 3D finite element model.
Volume 03 Issue 05-2023
30
American Journal Of Applied Science And Technology
(ISSN
–
2771-2745)
VOLUME
03
ISSUE
05
Pages:
28-31
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
7.063
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
Conclusion:
The study concludes with a summary of the key
findings and implications for future research in the field
of subcellular mechanics and tensegrity structures.
RESULTS
Our results showed that the tensegrity structure
exhibits a nonlinear response to external loads, with a
region of linear elasticity at low loads followed by
nonlinear deformation at higher loads. The mechanical
behavior of the structure was found to be sensitive to
the material properties of its components. In
particular, the stiffness of the struts and the pre-stress
of the cables were found to have a significant effect on
the overall mechanical behavior of the structure.
CONCLUSION
Our study provides insights into the mechanical
behavior of subcellular organelles and demonstrates
the potential of the tensegrity structure as a model for
their mechanical properties. The 3D finite element
model developed in this study can be used to
investigate the mechanical behavior of other
subcellular organelles and to design synthetic
structures with similar mechanical properties.
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