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THE ROLE AND PLACE OF ENTEROSORBTION IN THE COMPLEX
TREATMENT OF ACUTE INTESTINAL OBSTRUCTION
Inagamova S.D., student, 3 year – Treatment faculty
Supervisor: Boltayev Sh.Sh. – Senior lecturer of Department Surgery and
MFS, Pulatov M.M. – PhD, associate professor of Department Surgery and MFS,
Yunusov S.Sh. – PhD, of Department Surgery and MFS, Vali-zoda F.V. – assistant of
Department Surgery and MFS
Tashkent State dental institute
Progression of AIO and peritonitis of various etiologies contributes to disruption of the
gastrointestinal tract and metabolic processes in it with the development of intestinal paresis,
the formation of toxic substances and overfilling with the toxic liquid contents of its lumen
and lead to disturbances of microcirculation in the intestinal wall, have a detrimental effect on
the nerve elements and musculature of the intestinal wall and together with other numerous
pathogenetic changes in homeostasis cause the translocation of microorganisms and
endotoxins from the lumen of the intestine to the systemic circulation
The purpose
of our study was to evaluate the effectiveness of the use of naso-intestinal
decompression with enterosorption in the complex treatment of patients with AIO.
Materials and research methods.
The results of examination and treatment of 63
patients with non-tumor origin AIO, hospitalized in the surgical department base of the
Surgery and Military field surgery in 2018-2024 are analyzed. The most common cause of
AIO was adhesive intestinal obstruction - in 57.1% patients, strangulation IO in 28.6% and
obturation IO in 11.1%. Depending on the treatment measures used, patients were divided into
2 groups: 25 patients made up a control group without sorbent, 38 patients with enterosorbent
were included in the main group.
Patients of the main group received a complex of therapeutic measures supplemented
with enterosorption. As an enterosorbent, a Zerotox preparation based on hydrolytic lignin of
cottonseed husks (manufactured by the A. Sultanov Uzbek Scientific Research Chemical and
Pharmaceutical Institute, Tashkent) was used. To do this, a suspension was prepared based on
10.0 g zerotox powder per 1000 ml of a 0.9% sodium chloride solution.
Results and its discussion.
In patients of the main group after the application of
enterosorbent, on the 3rd day after the operation in the exudate of the abdominal cavity the
local factors of protection were restored, approaching the control values.
Analysis of the results of treatment showed that due to a differentiated approach to the
treatment of AIO in the main group, postoperative complications occurred only in 5 (13.2%)
patients 1 (2.6%) died of myocardial infarction.
Conclusion.
After the application of
enterosorbent, the quantitative and qualitative composition of the intestinal microflora is
significantly improved, an earlier cessation of exudation into the abdominal cavity is observed,
as well as positive shifts of all local defense indicators already on the 3rd day after the
operation, which significantly reduces the number of postoperative complications and
lethality.
REFERENCES:
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1.
Пазилова, С. А., Абдужабарова, З. М., Шадиева, М. С., & Шахизирова, И. Д.
(2020). ОСОБЕННОСТИ МОРФОЛОГИЧЕСКИХ ИЗМЕНЕНИЙ СЛИЗИСТОЙ
ОБОЛОЧКИ ЖЕЛУДКА И ДВЕНАДЦАТИПЕРСТНОЙ КИШКИ ПРИ НР
АССОЦИИРОВАННОЙ ПАТОЛОГИИ ГАСТРОДУОДЕНАЛЬНОЙ ЗОНЫ У ДЕТЕЙ.
In Университетская наука: взгляд в будущее (pp. 631-636).
2.
Khalmukhamedov, J., Rasulev, Y., Daminov, B., & Yoo, T. H. (2025). WCN25-1089
THE USE OF ACETAMINOPHEN FOR PAIN RELIEF IN PATIENTS WITH STAGE 5
CHRONIC
KIDNEY
DISEASE
ON
HEMODIALYSIS. Kidney
International
Reports, 10(2), S97.
3.
Агзамова, Ш. А. "Клеточный и гуморальный иммунитет у детей раннего
возраста, инфицированных внутриутробно цитомегаловирусом и вирусом простого
герпеса." Вятский медицинский вестник 2 (46) (2015): 13-17.
4.
Abdusalamovna, Agzamova Shoira. "Factor analysis of cause-effect relationship of
fetal infections of children by the agents of TORCH—complex." European science review 5-
6 (2015): 43-46.
5.
Агзамова, Ш. "Артериальная гипертензия у детей: Полиморфизм BsmI
(rs1544410) гена VDR и витамина D." Актуальные вопросы практической
педиатрии 1.1 (2023): 17-19.
