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EVALUATING THE IMPACT OF FERTILITY PRESERVATION
PROGRAMS ON QUALITY OF LIFE AMONG ONCOLOGY PATIENTS:
INSIGHTS FROM THE FACT-G QUESTIONNAIRE
Khodjaeva N.Kh.
1,2
Tashkent State Dental Institute
1
, Medifarm EKO Private Clinic
1,2
Introduction:
As advancements in oncology have dramatically improved patient
survival rates, quality of life (QoL) has emerged as a critical concern for patients, particularly
for younger women facing reproductive challenges. Aggressive treatments such as
chemotherapy and radiation therapy may lead to fertility loss, adversely affecting life
satisfaction. Fertility preservation programs are gaining prominence as essential components
of treatment, offering women the opportunity to retain their reproductive functions and
enhance their quality of life.
Materials and Methods:
This comparative and descriptive study evaluated QoL
among oncology patients participating in fertility preservation programs against a control
group not receiving such interventions. The study included 140 patients, divided into a main
group (n=75) who engaged in fertility preservation and a control group (n=65) who did not.
Quality of life was measured using the FACT-G questionnaire, which assesses various
domains including physical wellbeing, emotional and social wellness, and daily life
satisfaction. Statistical analyses were performed using appropriate methods to compare the
groups.
Results:
The findings revealed significant differences in QoL between the two groups
(p < 0.001) across all measured domains. Notably, patients with lymphoma reported the
highest QoL scores, while those with gynecological cancers showed the lowest. Physical well-
being scores were highest among lymphoma patients (median: 14.00), compared to lower
scores in those diagnosed with gynecological cancer (median: 12.00). Emotional and social
wellness also reflected lower satisfaction levels among gynecological cancer patients (median:
10.00) compared to their counterparts with lymphoma (median: 14.00). The overall QoL score
also corroborated these observations, with lymphoma patients achieving a median score of
64.00 versus 49.00 in the gynecological cancer group.
Conclusion:
This study highlights the significant impact of fertility preservation programs on
the quality of life for oncology patients, revealing that the type of oncological pathology
notably influences their overall satisfaction. Specifically, patients diagnosed with lymphoma
experience higher emotional and social wellbeing compared to those with gynecological
cancers. These results underscore the critical need for integrating fertility preservation
programs into standard treatment protocols for cancer patients, as they can profoundly enhance
the psychological and emotional health of women facing fertility threats due to oncological
therapies.
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