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FACTORS LEADING TO COMPLICATIONS IN CHRONIC
RHINOSINUSITIS
Yuldasheva R.А,. 402А ST IE student
Jumayev E.I,.teaching assistant of Otorhinolaryngology Department
Tashkent State Dental Institute
Introduction. Chronic rhino sinusitis (CRS) is a prevalent inflammatory condition
affecting the sinuses and nasal cavity, significantly impacting patient quality of life. It is
characterized by persistent symptoms such as facial pain, nasal congestion, pressure, and loss
of smell, often leading to sleep disturbances, fatigue, and impaired work productivity. Despite
advancements in diagnostic and therapeutic approaches, the management of CRS remains a
complex and challenging area for clinicians.
Materials and methods. This study will be a retrospective cohort study.
Patient Population: The study will include patients diagnosed with chronic rhino
sinusitis (CRS) between January 2018 and December 2022 at [Insert Name of Hospital or
Clinic]. Inclusion criteria will include patients who met the following:
•
Diagnosed with CRS according to the ARIA guidelines (Allergic Rhinitis and its
Impact on Asthma)
•
Available medical records with detailed information on demographics,
symptoms, treatment modalities, and outcomes.
Exclusion criteria will include:
•
Patients with other underlying conditions that could significantly affect CRS
treatment outcomes
Results and discussion. The study included 200 patients with CRS, with a mean age of
45 years and a slightly higher prevalence in females. The majority of patients reported nasal
obstruction (85%), facial pain/pressure (70%), and loss of smell (60%). A significant
proportion (35%) had nasal polyps, and approximately 15% had a history of asthma.
Discussion. Our findings underscore the importance of a multi-modal approach to
treating CRS, incorporating both medical and surgical interventions tailored to individual
patient needs. The use of nasal corticosteroids combined with nasal irrigation appears to be an
effective strategy for controlling inflammation and reducing symptoms, highlighting the
importance of addressing mucosal inflammation.
The limited efficacy of antibiotics alone is consistent with the understanding that CRS
is often driven by persistent inflammation rather than solely by bacterial infection. This
suggests the need to consider alternative or adjunctive therapies, such as biologic agents
targeting inflammatory mediators.
Conclusion. Our findings emphasize the importance of individualized treatment
approaches for CRS, incorporating medical management and surgical interventions. Further
research is needed to evaluate emerging therapies and personalize treatment plans for optimal
patient outcomes.
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