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PATHOMORPHOLOGICAL TYPES OF BRAIN ASTROCYTOMA
DISEASE AND TOPOGRAPHIC-ANATOMICAL MEETING
Beknazarov H.J., Rasulov H.A., Nishanov D.A.
Republican Center of Specialized Neurosurgery Scientific Practical Medicine,
Tashkent pediatric medical institute, Tashkent, Uzbekistan.
Data were analyzed from 971 patients with histological types of
astrocytomasregistered in the Republican Center of Specialized Neurosurgery
Scientific Practical Medicinebetween 2016 and 2020.
Our task was to analyze and evaluate the pathomorphological types and
anatomical location of astrocytomas, the most common brain glial tumors.
Patients received treatment. A retrospective analysis of the pathomorphological
types of astrocytoma was conducted in them.
According to the results, the age of the patients is from 1 to 70 years, of
which 315 (32.4%) were men, 656 (67.5%) were women, and 95 (9.7%) were
under the age of 20. All of the above patients underwent neurosurgery. If we look
at the topographic-anatomical location of astrocytomas. 674 cases (69.4%) in the
cerebral hemisphere, of which
–
340 (35.0%) of astrocytomas located in the right
cerebral hemisphere, 334 (34.3%) astrocytomas located in the left cerebral
hemisphere, 321 (321) in the frontal lobe of the cerebral hemisphere 33.0%), 158
(16.2%) in the right forehead lobe, 163 (16.7%) in the left forehead lobe. 165
(16.9%) in the top lobe, 91 (9.37%) in the right lobe, 74 (7.6%) in the left lobe.
153 (15.7%) in the temporal region, 72 (7.4%) in the right temporal region, 81
(8.3%) in the left temporal region.There were 35 (3.6%) cases in the occipital
region, 19 (1.9%) in the right occipital region, 16 (1.6%) in the left occipital
region. 38 (3.9%) astrocytomas were found in the lateral ventricles of the brain,
of which 18 (1.8%) were found in the right lateral ventricle of the brain, and 20
(2.0%) were observed in the left lateral ventricle of the brain. A total of 63 (6.5%)
cases of astrocytoma were detected in the cerebellar hemispheres. Of these, 33
(3.4%) cases were detected in the right cerebral hemisphere and 30 (3.0%) cases
in the left cerebral hemisphere. 14 (1.4%) cases of astrocytoma were detected in
the cerebellum and brainstem angle. Right-sided 6 (0.6%), left-sided
–
8 (0.8%).
95 (9.8%) in the cerebellum vermiform branch and IV ventricle cavity, 23 (2.3%)
in the III
–
ventricle cavity, 22 (2.2%) in the thalamic branch, 17 (1.7%) in the
chiasma sellar branch, 12 (1.2%) in the corpus callosum. %), 2 (0.2%) cases of
astrocytoma were detected in the pineal area, 9 (0.9%) of the lateral ventricles,
and 2 (0.2%) cases in the medulla oblongata.The following types of astrocytoma
were identified during the pathomorphological analysis of operative and biopsy
samples taken from patients. The most frequently identified anaplastic
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astrocytomas were 553 (57%), fibrillary astrocytomas 201 (20.7%), diffuse
astrocytomas
–
60 (6.2%), pilocytic astrocytomas
–
51 (5.2%), protoplasmic
astrocytomas
–
33 (3.4%), Hemistocytic astrocytoma
–
29 (3.0%), pilomyxoid
astrocytoma
–
16 (1.7%), subependymar giant cell astrocytoma
–
14 (1.4%),
plemorphic xanthoastrocytoma
–
14 (1.4%) were identified.
In conclusion, it can be said that astrocytoma is more common in men than
in women, according to the topographic-anatomical location of the brain, it is
found more in the right hemisphere, more in the left frontal lobe of the frontal
lobe, more in the right lobe in the parietal lobe, more in the temporal lobe in the
left temporal lobe, in the cerebellum. and it was found to be more common in the
right hemisphere. According to the pathomorphological type, anaplastic
astrocytoma took the first places, followed by fibrillary astrocytomas and diffuse
astrocytomas.
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