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УДК: 615.5-002.2+615.89.615.26
REFINING THE THERAPEUTIC USE OF GOOSE FAT NATURAL OINTMENT IN
CHRONIC ALLERGIC SKIN CONDITIONS
Karimova F.R.
ORCID:
https://orcid.org/0009-0008-5021-0029
, feruza_karimova@bsmi.uz
Bukhara state medical institute, Bukhara. Uzbekistan.
Annotation.
According to current data from the World Health Organization (WHO),
allergic dermatitis affects approximately 15% of the global population. On a global scale, it
accounts for 20% to 40% of all dermatological conditions. The prevalence among pediatric
populations can reach up to 20%, while among adults, it ranges between 2% and 8%. The
condition affects males and females equally. Higher incidence rates are observed in regions
characterized by advanced industrial development, particularly those with extensive
chemical production. In European countries, contact dermatitis affects an estimated 10% to
15% of the adult population. Conversely, certain areas in Asia and Africa report relatively
lower prevalence rates. The burden of chronic allergic dermatitis is notably greater in
industrialized and urbanized settings, where it is estimated that 1 to 2 individuals per 100
may suffer from the condition.
Key words:
allergic dermatit, chemical industries, contact dermatit.
Abstract:
Allergic dermatitis remains one of the most widespread inflammatory skin
conditions globally. According to World Health Organization (WHO) statistics,
approximately 15% of the global population is affected by this condition, and it accounts for
20–40% of all dermatological disorders worldwide. The disease exhibits a particularly high
prevalence among children, with reported rates reaching up to 20%, while adult populations
demonstrate a prevalence ranging from 2% to 8% [1,2]. Allergic contact dermatitis, a
subtype of allergic dermatitis, is a non-infectious skin disorder characterized by immune-
mediated inflammatory responses following direct contact with specific allergens. Despite
its non-contagious nature, the disease poses a significant public health concern due to its
chronic and recurrent course [3]. Epidemiological studies indicate no significant difference
in prevalence between males and females. However, regional disparities in incidence are
observed. In industrialized countries, allergic dermatoses are reported in up to 30% of the
population, often linked to increased exposure to chemical irritants and environmental
allergens. Furthermore, in over one-third of affected individuals, the condition persists into
adulthood, negatively impacting quality of life and work productivity [4,5]. The growing
incidence of allergic skin diseases is attributed to multiple factors, among which the
immunosuppressive effects of modern lifestyle and environmental pollution play a central
role. Urbanization, industrial development, and widespread use of synthetic chemicals
contribute to immune dysregulation, making individuals more susceptible to allergic
reactions [6,7]. Given the limitations and side effects associated with long-term use of
corticosteroids and antihistamines, increasing attention has been directed toward natural
remedies with anti-inflammatory and regenerative properties. Among these, goose fat—a
traditional animal-based product—has shown promise due to its emollient, antioxidant, and
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skin barrier-restoring effects [8].
The purpose of the study:
to justify the effectiveness of using goose fat for the treatment of
allergic dermatitis.
Materials and methods.
62 patients with chronic allergic dermatitis participated in the
study. Patients were divided into two groups: a group treated with traditional medicine and a
group treated with folk medicine.
Patients participating in the study were diagnosed with chronic allergic dermatitis and were
in various stages of the disease. During the selection process, the age, gender, duration and
complexity of the disease were taken into account. Consent for participation and data
disclosure was obtained from patients prior to the study.
Patients were assessed with special quantitative scales (eg SCORAD - Scoring Atopic
Dermatitis) and other skin-related symptoms. Patients were evaluated for symptoms such as
itching, redness, inflammation, and dryness of the skin. Blood eosinophils, IgE levels and
other allergy-related indicators were analyzed.
Glucocorticoids and antihistamine drugs, as well as skin care products, were used as
traditional treatment. Natural ointment with goose fat was used for treatment using folk
medicine methods. The effectiveness of treatment was evaluated based on disease symptoms
or their absence. Disease recurrence, reduction or disappearance of symptoms were taken as
primary indicators. The research results were analyzed using statistical methods. These
analyzes were used to determine differences between treatment groups and to evaluate the
effectiveness of each treatment.
Results and discussion:
62 patients with chronic allergic dermatitis participated in the study.
These patients were divided into two groups: traditional medical treatment (TMT) group and
folk medicine methods (FMM) group. In the study, when IgE levels were checked before
and after treatment, the following results were noted:
Table 1
Dynamics of IgE amount during the study
Methods
of
treatment
IgE before treatment
Post-treatment IgE
Traditional treatment 200 IU/ml
182.4 IU/ml
Treatment
using
goose fat ointment
200 IU/ml
141.5 IU/ml
Both groups of patients in the study had the same amount of IgE before treatment,was equal
to 200 IU/ml. After traditional treatment, it decreased by 1.09 times to 170 IU/ml, and after
using goose fat ointment in patients treated with folk medicineThe amount of IgE decreased
to 140 IU/ml. This is a 1.4 times improvement compared to the initial indicators. When both
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methods were compared, it was confirmed that the use of Natural ointment with goose fat
was 1.2 times more effective.
Post-treatment changes in clinical symptoms in patients in the study group are presented in
figure 1.
Figure 1. The occurrence of clinical symptoms after therapeutic use of natural
ointment with goose fat in patients in the study group
Before treatment, hyperemia was noted in 25 (78.1%) patients, skin itching in 22 (68.8%),
skin dryness in 24 (75.0%) patients, and after treatment, the number of patients with
hyperemia decreased by 3.1 times. In 8 (25.0) patients, skin itching decreased by 1.57 times
in 14 (43.8%) patients, skin dryness was detected in 11 (34.4%) patients.
The occurrence of clinical symptoms after traditional treatment in patients in the study group
is presented in figure 2.
Figure 2. The occurrence of clinical symptoms after the use of traditional medicine in
patients in the study group
Before traditional treatment, hyperemia was noted in 27 (84.3%) patients, skin itching in 16
(75.0%) patients, and skin dryness in 16 (75.0%) patients. After treatment, the number of
patients with hyperemia decreased by 2.07 times to 13 ( 40.6) patients, skin itching and skin
dryness decreased by 1.5 times in 16 (50.0 %) patients, 16 (50.0 %) patients were observed.
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Figure 3 and 4 below shows the condition of patients before and after natural ointment with
goose fat treatment.
Figure 3. Allergic dermatitis on the face of patients before use natural ointment with
goose fat
Figure 4. Healing of allergic dermatitis on the face of patients after the use of natural
ointment with goose fat
Based on the results of the study, differences in effectiveness were noted between traditional
medical treatment and folk medicine methods. Patients in the TT group showed a slower
reduction in symptoms, but in some cases, adverse effects were observed. This condition
may be due to the strong effect of glucocorticoid and antihistamine drugs.
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On the other hand, in the group of folk medicine methods (natural ointment with goose fat),
the use of natural remedies gave good results in patients without adverse effects. These
methods have been shown to be harmless to the div and acceptable for long-term use.
Conclusions:
Prior to treatment with folk medicine methods, hyperemia was observed in 25
patients (78.1%), skin itching in 22 patients (68.8%), and dry skin in 24 patients (75.0%).
Following treatment, the number of patients with hyperemia decreased 3.1-fold to 8 patients
(25.0%), itching decreased 1.57-fold to 14 patients (43.8%), and dry skin was noted in 11
patients
(34.4%).
In the group receiving traditional medical treatment, hyperemia was initially observed in 27
patients (84.3%), itching in 24 patients (75.0%), and dry skin in 24 patients (75.0%). After
treatment, hyperemia decreased by 2.07 times to 13 patients (40.6%), while itching and
dryness were reduced by 1.5 times, each reported in 16 patients (50.0%).
A noticeable difference in therapeutic efficacy was observed between the traditional
treatment group and the group treated with folk medicine methods. Patients receiving
traditional pharmacological therapy demonstrated a comparatively slower resolution of
symptoms, and in some cases, adverse reactions were reported. These side effects may be
attributed to the potent pharmacodynamic effects of glucocorticoids and antihistamines
commonly used in conventional therapy. In contrast, the use of folk remedies, particularly
those based on natural ingredients such as goose fat, appeared to promote symptom relief
with fewer side effects and improved tolerability.
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1.
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3.
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