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ADVANTAGES OF TRADITIONAL MEDICINE METHODS IN THE
TREATMENT OF PSORIASIS
Karimova Feruza Rakhmatbaevna, Kayumov Kholmurod Naimovich
ORCID:
https://orcid.org/0009-0008-5021-0029
, feruza_karimova@bsmi.uz
Bukhara state medical institute, Bukhara. Uzbekistan.
Psoriasis is a genetically determined chronic skin disorder of multifactorial origin,
characterized by a recurrent course and immune-mediated inflammation, often accompanied
by musculoskeletal involvement. It is considered one of the most common dermatological
conditions. According to the World Health Organization (WHO), the global prevalence of
psoriasis ranges from 0.5% to 5.5% of the general population, depending significantly on the
climate and geographic region [1]. In recent years, psoriasis has increasingly been classified
as a systemic disease due to its impact not only on the skin but also on joints, kidneys, and
the liver—hence the term "psoriatic disease." Despite extensive research, the exact etiology
of psoriasis remains unclear. The disease is characterized by epidermal hyperproliferation,
impaired keratinocyte differentiation, and immune system dysregulation, leading to the
production of immune-dependent cytokines and mediators that trigger inflammatory
responses in the dermis [2]. Emotional stress and the psycho-emotional state of the patient
are considered major triggering factors. In addition, chronic infections can provoke the
initial manifestation of psoriasis. The disease frequently develops at sites of mechanical skin
trauma—such as cuts, scratches, injections, abrasions, or burns—or after the use of certain
medications (e.g., beta-blockers, non-steroidal anti-inflammatory drugs, or interferon).
Climatic conditions also play a significant role; almost all patients report that sun exposure
has a beneficial effect on their symptoms [1]. In recent years, novel and highly effective
treatments based on the pathogenesis of the disease have been developed. Although these
therapies may not lead to a complete cure, they help eliminate scaling lesions, which are a
major factor in the reduction of patients' quality of life [3]. Treatment typically involves a
comprehensive approach, including systemic and topical therapies, as well as
physiotherapeutic procedures. When choosing the appropriate treatment method, clinicians
take into account the stage of the disease, its clinical form, seasonal type (summer or winter),
extent of skin involvement, comorbid conditions, and the patient’s age [Olisova O.Yu. et al.,
2020].
The aim of this study
is to evaluate the effectiveness of traditional (folk) medicine methods
in the treatment of patients with psoriasis.
Materials and methods of research:
This study was conducted based on clinical
observations at the Bukhara Regional Dermatology Center and the Integrative and Folk
Medicine Clinic of the Abu Ali Ibn Sina Bukhara State Medical Institute. A total of 35
patients diagnosed with psoriasis were admitted and underwent comprehensive medical
examination. The average age of the patients was 41 years.
All patients underwent abdominal ultrasound (USG) to assess comorbid gastrointestinal
pathologies. The examination revealed the following associated conditions:
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Chronic cholecystitis in 20 patients (57%)
Fatty liver disease (hepatic steatosis) in 10 patients (29%)
Chronic pancreatitis in 5 patients (14%)
The patients were randomly divided into two treatment groups:
Group 1 (n = 17): Received standard medical therapy, which included topical
corticosteroids, systemic anti-inflammatory drugs, and vitamin therapy.
Group 2 (n = 18): Received combined therapy, which included standard treatment plus
traditional medicine approaches.
The folk medicine methods used in Group 2 included:
Application of goose fat ointment (GOOSE FAT+) to affected skin areas
Acupuncture sessions targeting systemic immune and dermatological meridians
Detoxification of the gastrointestinal tract using a blend of medicinal herbs (e.g., milk
thistle, chamomile, nettle)
Treatment duration for both groups was 10 days. Clinical outcomes were assessed based on
changes in skin lesions (erythema, scaling, thickness), subjective symptoms (itching,
discomfort), and patient-reported quality of life.
Results and Discussion
The treatment response was noticeably different between the two groups.
In Group 1 (n = 17), improvement in skin condition and clinical symptoms was
gradual and typically observed by Day 7 of therapy. Patients showed reduced scaling and
moderate relief from itching and erythema.
In Group 2 (n = 18), patients demonstrated earlier and more pronounced
improvements, with clinical signs improving as early as Day 3. These included significant
reduction in skin inflammation, itch relief, and overall patient satisfaction.
Comparative observation showed that the integration of traditional medicine methods
enhanced the speed and effectiveness of psoriasis treatment.
Suggestions for Visuals and Additional Enhancements
Table 2: Clinical Response by Day
Day of Therapy % Improvement in Group 1 % Improvement in Group 2
Day 3
15%
60%
Day 5
40%
80%
Day 7
70%
90%
Day 10
90%
95%
Patient Characteristics
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Parameter
Group 1 (n = 17) Group 2 (n = 18) Total (n = 35)
Average Age (years)
40.7 ± 5.6
41.3 ± 6.1
41.0 ± 5.8
Gender (M/F)
10 / 7
11 / 7
21 / 14
Comorbidities
Chronic cholecystitis 10 (59%)
10 (56%)
20 (57%)
Fatty liver disease
5 (29%)
5 (28%)
10 (29%)
Chronic pancreatitis 2 (12%)
3 (17%)
5 (14%)
Psoriasis Type
Vulgaris (plaque)
13 (76%)
14 (78%)
27 (77%)
Guttate
3 (18%)
3 (17%)
6 (17%)
Others (e.g., pustular) 1 (6%)
1 (5%)
2 (6%)
Disease Duration
Less than 1 year
4 (24%)
5 (28%)
9 (26%)
1–5 years
8 (47%)
9 (50%)
17 (49%)
More than 5 years
5 (29%)
4 (22%)
9 (26%)
Conclusion
The results of this study demonstrate that integrating traditional medicine methods—such as
goose fat ointment, acupuncture, and herbal gastrointestinal detoxification—into the
standard treatment of psoriasis can significantly enhance therapeutic outcomes. Patients in
the combined therapy group (Group 2) experienced earlier and more pronounced
improvements in clinical symptoms, such as reduced erythema, scaling, and itching, as early
as the third day of treatment. In contrast, those receiving only standard therapy (Group 1)
showed slower progress, with notable changes emerging around the seventh day.
These findings suggest that traditional medicine practices, when used in conjunction with
evidence-based modern therapies, can accelerate recovery, improve skin healing, and
enhance patient satisfaction. Furthermore, addressing gastrointestinal comorbidities and
supporting systemic detoxification appears to play a critical role in achieving more stable
and sustained remission in psoriasis patients.
The study also underscores the importance of a holistic and personalized approach to
treating chronic inflammatory skin diseases like psoriasis. Emotional stress, dietary habits,
and organ dysfunction—particularly of the liver and gallbladder—should be considered
when designing treatment plans. Folk medicine, when applied rationally and under medical
supervision, offers a valuable complementary strategy, especially in regions where
traditional healing practices are culturally accepted and accessible.
However, further large-scale, randomized controlled trials are necessary to confirm these
results and standardize protocols for the clinical use of traditional therapies in psoriasis
management. Future research should also focus on identifying the molecular mechanisms
behind the observed effects, optimizing treatment combinations, and ensuring safety and
long-term efficacy.
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In conclusion, the integration of traditional medicine methods with conventional
dermatological treatment holds promise as a cost-effective, accessible, and holistic strategy
for improving the quality of care for patients with psoriasis.
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