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THE IMPACT OF HYPERSALIVATION IN YOUNG CHILDREN DIAGNOSED
WITH CEREBRAL PALSY ON CHILD HEALTH AND THE ROLE OF
BOTULINUM THERAPY IN ITS TREATMENT
Assistant:
Ermatov Farhod Akhmedovich
Central Asian Medical University
International Medical University
Department of Pediatrics and Pediatric Surgery
Relevance:
Cerebral palsy (CP) is a neurological disorder in children characterized by motor and
movement impairments. One common complication is hypersalivation (excessive drooling),
which negatively affects the child's health. Hypersalivation can disrupt oral hygiene,
nutrition, psycho-emotional state, and social functioning. Botulinum therapy has emerged as
an effective method for treating hypersalivation. Our study investigates the benefits of
botulinum therapy in children with CP.
Objective of the Study:
1. To identify the physiological causes of hypersalivation in children diagnosed with
cerebral
palsy.
2. To evaluate the effectiveness of botulinum therapy in treating hypersalivation.
3. To study the impact of botulinum therapy on reducing hypersalivation and improving
children's health.
Materials and Methods:
The study involved 60 children aged 1 to 3 years diagnosed with cerebral palsy between
2023–2024. Each child was assessed for the degree and cause of hypersalivation. The
following
methods
were
used:
1. Clinical Examination: Assessment of hypersalivation severity and identification of
neurological
and
motor
symptoms.
2. Neurological Examination: Investigation of the neurological causes of hypersalivation in
children
with
cerebral
palsy.
3. Botulinum Therapy: Application of botulinum toxin to inhibit salivary gland function and
evaluate its effect on reducing hypersalivation.
Results and Discussion:
The findings indicate that hypersalivation in children with CP is primarily associated with
motor
and
neurological
disorders.
Key
contributing
factors
include:
1. Neurological Disorders: Impairment in the brain’s motor control centers initiates
hypersalivation. These indicators are notably high in children with CP.
2. Dysfunction in the Digestive System: Gastroesophageal reflux or other feeding-related
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issues
can
lead
to
hypersalivation.
3. Neural Signal Transmission Issues: Any neurological disruption can exacerbate
hypersalivation.
Botulinum therapy proved effective, reducing salivation within 3–6 weeks. Study results
showed high efficacy, confirming botulinum therapy's critical role in managing
hypersalivation in young children.
Conclusion:
Treating hypersalivation in children with cerebral palsy is of great importance. Botulinum
therapy is an effective method that reduces salivation by inhibiting salivary glands.
Treatment should be personalized based on each child’s neurological condition.
References:
1. Mazzone, L., et al. “Botulinum Toxin for Drooling in Children with Cerebral Palsy.”
Pediatric
Neurology,
2017;
68:
1–8.
2. Ferro, A., et al. “Management of Drooling in Children with Neurological Disabilities: A
Review of Treatment Options.” European Journal of Paediatric Neurology, 2018; 22(4):
678–684.
3. WHO. “Management of Neurological Disorders in Children.” Geneva: World Health
Organization,
2020.
4. El-Salem, K., et al. “Efficacy of Botulinum Toxin in the Treatment of Drooling in
Children with Cerebral Palsy.” Pediatric Rehabilitation, 2019; 12(3): 139–144.
5. Pavone, V., et al. “Treatment of Drooling in Cerebral Palsy: New Insights into Botulinum
Toxin Use.” Neurorehabilitation and Neural Repair, 2021; 35(2): 152–158.
