Volume 03 Issue 11-2023
23
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
This article discusses the clinical characteristics and causative factors of colostasis in children. Conductedanalysis of
anamnestic data149 patients, studied the results of clinical and anamnestic data and a comprehensive clinical
examination.
KEYWORDS
Nutritional and emotional factors, constipation, colostasis, children.
INTRODUCTION
Constipation is a disorder of intestinal function,
expressed in a slowdown (compared to the individual
physiological norm) of the age-related rhythm of
defecation, its difficulty, systematically insufficient
bowel movement and/or changes in the shape and
character of stool [4,5,8,9]. When analyzing the
literature data, there is quite a huge amount of
material devoted to the problems of constipation in
children, but there is no systematic, comprehensive
review and analysis.Until today, there are no clear
indications for surgical treatment of colostasis, no
timing, and the problem of determining clear
indications and contraindications for surgery has not
been solved.[3,8,9,17].When performing interventions,
surgeons are based on their own experience and
knowledge gleaned from well-known
literary
sources[1,5,16,22].That is why there are still a large
number of intra- and postoperative complications;
there are no standards for the supervision of patients
before
and
after
surgical
procedures[2,10,12,19,21].There are no diagnostic or
clinical criteria for colostasis in the age aspect in
Research Article
ANALYSIS OF CHARACTERISTICS OF CONSTIPATION IN CHILDREN
Submission Date:
November 03, 2023,
Accepted Date:
November 08, 2023,
Published Date:
November 13, 2023
Crossref doi:
https://doi.org/10.37547/ijmscr/Volume03Issue11-04
Nuriddinov Sadriddin Saifiddinovich
Bukhara State Medical Institute. Uzbekistan
Journal
Website:
https://theusajournals.
com/index.php/ijmscr
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 03 Issue 11-2023
24
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
children, which determines the relevance of
conducting in-depth experimental and clinical research
in this direction[3,11,15,18].
Currently, thanks to technological progress, modern
imaging methods provide a fairly high degree of
diagnosis
of
congenital
pathology
of
the
gastrointestinal tract, both at the prenatal and
neonatal stages of development, allowing early
detection of defects that may require emergency and
(or) planned correction[9,13,15,18]. Diagnosis of
patients subject to colon resection is not difficult, but
the management of such patients still remains
controversial [5,14,20].
Purpose of the study. Study of some clinical features of
colostasis in children.
Materials and research methods. This work is based on
examination and treatment data of 149 sick children
aged from 1 month to 14 years with colostasis. An
analysis was carried out of patients who received
treatment in the department of pediatric surgery of
the Bukhara Regional Children's Multidisciplinary
Medical Center, which is the clinical base of the
Department of Pediatric Surgery of the Bukhara State
Medical Institute for the period 2012 - 2022.
The main criterion for including patients in our study
was the presence of colostasis, patients’ complaints
about the lack of independent stool. The work does
not include patients with the total form of
Hirschsprung's disease.
All children underwent a comprehensive examination
used in pediatric surgery, including clinical, laboratory,
and X-ray examinations: detailed study and history
taking, clinical objective examination, and, if necessary,
rectal digital examination; general clinical tests -
general analysis of blood, stool and urine; X-ray
contrast study - irrigography of the colon with barium
sulfate solution according to the method of A.I.
Lenyushkina. Sphincteromanometry was performed to
determine sphincter tone in some patients.
Results and discussion. All children underwent a
comprehensive examination used in pediatric surgery,
including clinical, laboratory, and X-ray examinations:
detailed study and history taking, clinical objective
examination, and, if necessary, rectal digital
examination; general clinical tests - general analysis of
blood, stool and urine; X-ray contrast study -
irrigography of the colon with barium sulfate solution
according to the method of A.I. Lenyushkina.
Sphincteromanometry was performed to determine
sphincter tone in some patients.
When analyzing data on the distribution of patients
with colostasis depending on gender and age, boys
predominated - 82 (55.0%), compared to girls - 67
(45.0%).When dividing patients by age categories,in
the age group from 1 year to 4 years, making up 34
Volume 03 Issue 11-2023
25
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
(22.8%) for boys and 31 (20.8%) for girls, in the age
group from 5 years to 9 years, boys accounted for 20
(13.4%), girls of this age made up 12 (8.0%) of the
examined
patientswere
predominantsick
male
children (Table 1).In our opinion, functional
constipation affects the quality of life of patients
starting from the age of one year and is a reason for
hospitalization in a hospital to determine the etiology
of constipation.
Distribution of patients with colostasis depending on gender and age
Table 1
Note:*- children of the early postnatal period of development are not included in our study.
The smallest number of patients was aged 10-14 years
–
7 (4.8%), which is associated with low parents’
seeking medical help and acquiring skills to control
stool frequency, as well as relative adaptation to the
pathological condition in children of high school age.
In almost all studies of children with constipation,
there was a higher prevalence of boys with
constipation compared to girls.This may not be the
result of a true difference in frequency, but due to
differences in seeking medical advice and treatment.
Analysis of the nature of constipation showed the
predominance of patients with constipation of an
organic nature. When distributed according to the
origin of constipation, functional constipation
accounted for 22 (15%), and organic constipation
accounted for 127 (85%), which is due to the fact that
before hospitalization, patients undergo partial
examination in an outpatient setting (Fig. 1).
To make a diagnosis, we adhered to the classification
of A.I. Khavkin (2000), which identifies the following
definition criteria: compensated - stool once every 2-3
days, usually independent, but with a feeling of
incomplete emptying and flatulence - 52 (34.9% );
subcompensated
–
stool once every 3-5 days while
taking laxatives and a cleansing enema
–
74 (49.7%);
decompensated - there is no independent stool, its
Floor
Age of patients
(WHO classification 2021)
0-27
days
01
–
11 month 01-4
years
5
–
9
years
10-14
years
Total:
n, %
boys
*
24
16.1%
34
22.8%
20
13.4%
4
2.7%
82
(55%)
girls
*
21
14.1%
31
20.8%
12
8.0%
3
2.1%
67
(45%)
Total:
-
45
30.2%
65
43.6%
32
21.4%
7
4.8%
149
(100%)
Volume 03 Issue 11-2023
26
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
delay can reach 10 or more days, accompanied by
abdominal pain, intoxication, emptying is possible
using siphon or hypertensive enemas - 23 (15.4%).
Fig.1. Distribution of patients depending on the origin of constipation
The predominance of the compensated and subcompensated stages of constipation in the examined sick children
was established (Fig. 2).
Fig.2.Distribution of patients depending on the stage of colostasis
In our studies, in 149 patients examined, the following
comorbidity with constipation was revealed (Table 2),
which influenced the course of the underlying disease.
At the same time, the most common comorbid
background in children with colostases were children
with dolichosigma,56 (37.6%), anemia - which
amounted to 40 (26.8%) of the examined patients, as
Функциональные
Органические
34.90%
49.70%
15.40%
Компенсация
Субкомпенсация
Декомпенсация
Volume 03 Issue 11-2023
27
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
well as dolichocolon 28 (18.9%) and megacolon 28
(18.2%).
Frequency of comorbidity in sick children with colostasis
Table 2.
Nosology
Number of patients
Abs
%
Anemia
40
26.8
Hirschsprung's disease
10
6.7
Dolichosigma
56
37.6
Dolichocolon
28
18.9
Megacolon
27
18.2
Payer's disease
7
4.7
Hilaiditi syndrome
3
2.0
Ectopia ani
2
1.3
Atresia ani et recti
1
0.7
Stenosis ani
3
2.0
SPO BPPR*
14
9.4
Total
191
* note: SPO BPPR - Condition after abdominal-perineal proctoplasty surgery for Hirschsprung's disease, anorectal
malformation, etc.
CONCLUSION
Thus, based on the results of the study and the study
of regional characteristics of chronic constipation in
the Bukhara region, it was established that when
distributed by gender and place of residence, boys
aged from one year to 9 years of age are more likely to
suffer.
Volume 03 Issue 11-2023
28
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
Among the causative factors leading to constipation,
the highest frequency is represented by pathologies of
the sigmoid colon (dolichocolon, megacolon,
dolichosigma) - 75.2% of cases.
REFERENCES
1.
Акилов Х.А., Саидов Ф.Х. Диагностика и
методы
лечения
мегаколон
у
детей
//Shoshilinch tibbiyot axborotnomasi, 2016, IX
(3).-
с.125
-131.
2.
Белоусова О.Ю. Современный взгляд на
функциональные запоры у детей раннего
возраста: особенности вскармливания и
принципы немедикаментозной коррекции/
/Журнал Здоровье ребенка, ISSN 2224
-0551,
N1 (60).-2015.-140-148.
3.
Григорьев
К.И.
Запоры
у
детей
//
Медицинская сестра. Профессия:теория и
практика
-
№2,
-2014.-
с.37
-42.
4.
Запор.
Клинические
рекомендации,
Российская
гастроэнтерологическая
ассоциация, Ассоциация колопроктологов
России
- 2020.-
26 с.
5.
Комарова О.Н., Хавкин А.И. Алгоритм
обследования и лечения детей раннего
возраста с запорами // РМЖ. 2016. № 6. С.
358
–
360.
6.
Ленюшкин
А.И.
Хирургическая
колопроктология
детского
возраста.
М..1999, 366 с.
7.
Раупов, Ф. С., & Мехриддинов, М. К. (2020).
Функциональные
изменения
после
обширных резекций толстого кишечника у
детей. Проблемы биологии и медицины, (1),
116.
8.
Руденко Н.Н. Лечение хронического запора:
от теории к практике / Н.Н. Руденко, О.В.
Томаш, А.Э. Дорофеев // Новости медицины
и
фармации.
—
2013.
—
№
457.
Гастроэнтерология. —
С. 37
-39.
9.
Ф.С., Р. ., & С.С., Н. . (2023). Клинико
-
рентгенологическая
характеристика
колостаза у детей. Research Journal of
Trauma and Disability Studies, 2(5), 225
–
233.
Retrieved
from
http://journals.academiczone.net/index.php/rjt
ds/article/view/91
10.
Хавкин А. И. Коррекция функциональных
запоров у детей. Росс. вестн. перинатол. и
педиатрии. 2012; 4 (1): 127–
130.
11.
Allen AP, Dinan TG, Clarke G, Cryan JF. A
psychology
of
the
human
brain
–
gut
–
microbiome axis. Soc Personal Psychol
Compass.
2017
Apr;11(4):e12309.
doi:
10.1111/spc3.123-09.
12.
Benninga S, Nurko MA, Faure C, Hyman PE,
James Roberts ISt, Schechter NL. Childhood
Functional
Gastrointestinal
Disorders:
Neonate/Toddler. Gastroenterology, 2016,
150(6): 1443
–
1455.
Volume 03 Issue 11-2023
29
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
13.
Vandenplas Y, Levy E, Lemmens R, Devreker T.
Функциональный запор у детей. Педиатрия
(Прил. к журн. Consilium Me
dicum). 2017; 1:
50
–
57.
14.
Walter HA, Rajindrajith S, Devanarayana NM et
al. OP-1 prevalence of functional constipation in
infants and toddlers in Sri Lanka. J Pediatr
Gastroenterol Nutr 2015; 61 (4): 541.
15.
Henry's Clinical Diagnosis and Management by
Laboratory Methods, 23e by Richard A.
McPherson MD MSc (Author), Matthew R.
Pincus MD PhD (Author). St. Louis, Missouri :
Elsevier, 2016. Page 974.;
16.
Raupov
F.S.
(2023).
CLINICAL
AND
RADIOLOGICAL
CHARACTERISTICS
OF
COLOSTASIS IN CHILDREN. American Journal
Of Biomedical Science & Pharmaceutical
Innovation,
3(05),
48
–
57.
https://doi.org/10.37547/ajbspi/Volume03Issue
05-07.
17.
Raupov, F. S. (2022). Morphological Aspects of
the Colon of Human and White Laboratory
Rats. Central Asian Journal of Medical and
Natural Science, 3(2), 243-247.
18.
Raupov, F. S. (2020). Possible dysfunctions of
the large intestine after resection in children.
Problems of biology and medicine,(3), 119(18),
42-46.
19.
Raupov, F. S. (2022, September). Preventive
measures of complications of colon resection
in children in consideration of morphological
features.
In
"
ONLINE-CONFERENCES"
PLATFORM (pp. 41-42).
20.
Khamraev, A. (2020). Zh., Rakhmonov DB,
Raupov FS. Fecal incontinence after repeated
colon surgery in children. anatomical and
physiological reflections/Problems of biology
and medicine, (5), 122. Wang B., Duan R., Duan
L. Prevalence of sleep disorder in irritable
bowel syndrome: A systematic review with
meta-analysis. Saudi J. Gastroenterol. 2018
May-Jun;24 (3):141-150.
21.
Yeh H.W., Chien W.C., Chung C.H. Risk of
psychiatric disorders in irritable bowel
syndrome-A nationwide, population-based,
cohort study. Int. J. Clin. Pract. 2018 Jul;72(7).
22.
A.T. Ahmedov, F.J. Kamolov, J.R. Sharipov, L.A.
Narziev.
(2023).
PREDICTORS
OF
CARDIOVASCULAR
COMPLICATIONS
IN
PATIENTS WITH CHRONIC ISCHEMIC HEART
DISEASE AFTER BYPASS SURGERY. SCIENCE
AND INNOVATION IN THE EDUCATION
SYSTEM,
2(4),
164
–
168.
https://doi.org/10.5281/zenodo.7787690
23.
A.T. Akhmedov, & L.A. Narziev. (2023).
PREDICTORS
OF
CARDIOVASCULAR
COMPLICATIONS IN PATIENTS WITH CHRONIC
ISCHEMIC HEART DISEASE AFTER BYPASS
SURGERY. International Journal of Medical
Sciences And Clinical Research, 3(03), 68
–
77.
Volume 03 Issue 11-2023
30
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
https://doi.org/10.37547/ijmscr/Volume03Issue
03-10
24.
A.T.Ahmedov,
F.J.Kamolov,
J.R.Sharipov,
L.A.Narziev. (2023). ECHOCARDOGRAPHIC
FEATURES OF PATIENTS AFTER COVID-19
PNEUMONIA. ACADEMIC
RESEARCH
IN
MODERN
SCIENCE,
2(10),
37
–
41.
https://doi.org/10.5281/zenodo.7787702
25.
Ahmedov, A., & Kamolov, F. (2023).
ECHOCARDOGRAPHIC CHANGES IN PATIENTS
WITH A SURVEY OF PNEUMONIA ASSOCIATED
WITH CORONAVIRUS INFECTION COVID-19.
International Bulletin of Medical Sciences and
Clinical Research, 3(3), 110
–
115. Retrieved from
https://researchcitations.com/index.php/ibmsc
r/article/view/883
26.
Akhmedov
A.T.
(2022).
COMPARATIVE
EVALUATION
OF
IMMUNOLOGICAL
PARAMETERS OF LABORATORY ANIMALS
WITH THYMUS AUTOIMPLANTATION IN THE
DYNAMICS OF OBSERVATION. International
Journal of Medical Sciences And Clinical
Research,
2(11),
12
–
18.
https://doi.org/10.37547/ijmscr/Volume02Issue
11-03
27.
Djalilova,
Z.
(2023).
PEDAGOGICAL
EDUCATIONAL
TECHNOLOGY:
ESSENCE,
CHARACTERISTICS
AND
EFFICIENCY.
Академические
исследования
в
современной науке, 2(23), 29
-38.
28.
Djalilova, Z. (2023). THE SIGNIFICANCE AND
POSITION OF TEACHING METHODS IN
PROFESSIONAL TRAINING. Solution of social
problems in management and economy, 2(10),
31-42.
29.
Djalilova, Z. (2023). THE USE OF LATIN
TERMINOLOGY
IN
MEDICAL
CASE.
Академические
исследования
в
современной науке, 2(14), 9
-15.
30.
Navruzova,
Sh.I.,
Akhmedov,
A.T.
“AUTOIMPLANTATION
OF
THYMUS
IN
SURGICAL CORRECTION OF CONGENITAL
HEART DEFECTS" CENTRAL ASIAN JOURNAL
OF MEDICAL AND NATURAL SCIENCES, - 2021.
–
Vol. 2.3 - (2021).
–
P.: 88-98.
31.
Navruzova,
Sh.I.,
Akhmedov,
AT
“"AUTOIMPLANTATION OF
THYMUS IN
SURGICAL CORRECTION OF CONGENITAL
HEART DEFECTS." CENTRAL ASIAN JOURNAL
OF MEDICAL AND NATURAL SCIENCES, - 2021. -
Vol. 2.3 - (2021).
–
P.: 88-98.
32.
Ахмедов А.Т., Особенности иммунной
системы при врожденных пороков сердца, //
EUROPEAN JOURNAL OF MODERN MEDICINE
AND PRACTICE.
–
2022. Vol. 2 No. 3 EJMMP.
–
С.
35-40. [Akhmedov A. T., Features of the
immune system in congenital heart defects, //
EUROPEAN JOURNAL OF MODERN MEDICINE
AND PRACTICE.
–
2022. Vol. 2 no. 3 EJMMP.
–
pp. 35-40 [in Russian]
Volume 03 Issue 11-2023
31
International Journal of Medical Sciences And Clinical Research
(ISSN
–
2771-2265)
VOLUME
03
ISSUE
11
P
AGES
:
23-31
SJIF
I
MPACT
FACTOR
(2021:
5.
694
)
(2022:
5.
893
)
(2023:
6.
184
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
33.
Ахмедов
А.Т.,
Сравнительная
оценка
иммунологических
параметров
лабораторных животных аутоимплантации
тимуса
в
динамике
наблюдения,
//
EUROPEAN JOURNAL OF MODERN MEDICINE
AND PRACTICE.
–
2022. - Vol. 2 No. 3: EJMMP. C.
40-45
[Akhmedov
A.
T.,
Comparative
evaluation of the immunological parameters of
laboratory
animals
after
thymus
autoimplantation
in
the
dynamics
of
observation, // EUROPEAN JOURNAL OF
MODERN MEDICINE AND PRACTICE. - 2022. -
Vol. 2 no. 3: EJMMP. C. 40-45 in Russian]
34.
34.
Хидоятов, Б.А. Микроциркуляторное
русло кишечника и поджелудочной железы и
его особенности при экспериментальном
сахарном диабете / Б. А. Хидоятов, А. Т.
Ахмедов // Морфология. –
2008.
–
Т. 133. –
№
2.
–
С. 145
-146.
–
EDN JUTXTT.7.
Otto
CM, Pearlman AS Textbook of clinical
echocardiography. Philadelphia: WB Saunders
Co.; 1995:418.
35.
A.T.Akhmedov Kh.M.Aberaev Influence of
coronavirus
infection
covid-19
to
a
echocardographic changes in patients with a
surveyof
pneumonia
//
Академические
исследования в современной науке. –
2023. -
Том 2 № 20. –
стр. 57
-59
36.
AKHMEDOV , A. (2023). FUNCTIONING OF
IMMUNE
SYSTEM
OF
BABIES
WITH
CONGENITAL HEART DEFECTS. Евразийский
журнал медицинских и естественных наук,
3(6 Part 2), 103
–
110.
37.
Джалилова, З. (2023). The notion of illocution
in the theory of speech acts by John Austin.
Современные тенденции при обучении
иностранному языку в XXI веке, 1(1).
38.
Obidovna, D. Z. (2023). ADAPTING TEACHING
METHODS
TO
MODERN
EDUCATIONAL
TRENDS: PEDAGOGICAL ASPECT. International
Journal of Pedagogics, 3(10), 72-77.
39.
Akhmedov, A., & Aberaev , K. (2023).
INFLUENCE OF CONGENITAL HEART DEFECTS
IN A FUNCTIONING OF IMMUNE SYSTEM OF
BABIES. International Bulletin of Medical
Sciences and Clinical Research, 3(8), 15
–
21.
40.
Nuriddinov
S.S.
(2023).
CLINICAL
CHARACTERISTICS OF CHRONIC COLSTASIS IN
CHILDREN. International Journal of Medical
Sciences And Clinical Research, 3(05), 75
–
83.
https://doi.org/10.37547/ijmscr/Volume03Issue
05-11
