Vol. 2 No. 12 (2022): Volume 02 Issue 12

Vol. 2 No. 12 (2022): Volume 02 Issue 12
Published: 01-12-2022

Articles

21-28 33 17

STRUCTURE OF THE METABOLIC SYNDROME AND COMORBID BACKGROUND IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

M.B. Kholjigitova

This article discusses structure of the metabolic syndrome and comorbid background in patients with chronic obstructive pulmonary disease. In addition, pharmacological and non-pharmacological treatment of COPD can mask the impact of comorbidities, including obesity, and this factor has not been considered in almost any large study.


 

09-20 45 9

PRE-CLINICAL STUDIES OF THE ANTITUBERCULOUS DRUG BIOMAYRIN

Mamatmusaeva N.E., Shomuratov Sh.А., Sagdullaev B.Т., Turaev А.S.

By chemical modification of polygalacturonic acid with anti-TB drugs isoniazid, ethambutol and rifampicin, the macromolecular system Biomayrin was obtained. Pharmaco-toxicological studies have ascertained that Biomayrin is less toxic than low-molecular counterparts and has pronounced anti-tuberculosis activity, and with a two-fold lower dose when calculating the active substance, it has identical activity with the combined anti-tuberculosis drug Mayrin. Pharmacokinetic studies have shown that with the introduction of Biomayrin, the therapeutic concentration of the active ingredients (isoniazid, ethambutol and rifampicin) in the blood lasts longer than that of their low-molecular counterparts. It should also be noted that the chemical binding of isoniazid to the polysaccharide matrix slows down its metabolism to therapeutically inactive acetylisoniazid.

04-08 37 21

TUMORS OF THE LEFT VENTRICLE CLINICAL CASE

Munira S. Mahmudova, Surayyo M. Shukurdjanova, Nigora B. Nuritdinova

Heart tumors are rarely met in clinic practice. They are divided into benignant and malignant tumors. In this article is given the clinical case of patient, which had the diagnosis of Ischemic heart disease (IHD) postinfarction cardiosclerosis (PICS) during years due to the complaints of pain in the area of heart and locus changes in ECG. The echocardiogram showed up two tumors in the left ventricle of the heart.


 

01-03 46 56

HYPOXIA. ETIOLOGY, PATHOGENESIS, TYPES OF HYPOXIA. DISTRIBUTION OF TYPES OF HYPOXIA, DEVELOPMENT SPEED AND DEGREE. PREVENTION AND TREATMENT OF HYPOXIA

Qarshiyev Mashxur Shuxrat o’g’li, Rafiqov Dostonbek Sodig’ali o’g’li

In this article, the definition of hypoxia, the factors that cause it, the conditions observed in the body during hypoxia, and the definition of hypoxia. Ideas and concepts about the widespread use of methods of prevention and treatment of hypoxia in modern medicine are presented.