The Andijan Uprising of 1898 was a significant anti-colonial resistance movement against Russian rule in Turkestan. Led by Dukchi Eshon, a religious leader advocating for the restoration of Islamic governance, the uprising was a response to increasing economic hardship, land dispossession, and cultural suppression under Russian imperial policies. This paper examines the causes, execution, and consequences of the rebellion, utilizing primary sources and historical accounts to analyze the role of Dukchi Eshon and the broader implications of the revolt. The study aims to contribute to a deeper understanding of resistance movements in Central Asia and their place within the larger framework of anti-colonial struggles.