The state of the hemostasis system during endoprosthetics of the joints of the lower extremities operated on under conditions of general anesthesia in people with high anesthetic risk

Endoprosthetics of the joints of the lower extremities is considered one of the most successful orthopedic procedures and more than a million such operations are performed every year in the world (4). It is predicted that by 2020, arthroplasty of the joints of the lower extremities will exceed more than one million per year in the United States alone (2). Historically, general anesthesia has been the gold standard in orthopedic surgery. At present, in research practice and in discussing the timely prevention of cardiovascular diseases, especially coronary heart disease, which occupies the first place among the causes of population death worldwide, it is necessary to take into account age-related changes that occur in the anatomical structures of the heart and the vessels supplying it. In the References:there is evidence of agerelated changes in coronary vessels. According to (1), in people of the second period of middle age and the elderly, age-related changes in the vascular wall are noted. According to (5), there is a direct correlation between the degree of tortuosity of the coronary vessels and the age of the patient