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POTENTIAL RISK FACTORS IN PATIENTS WITH AMI/ACS
Madjidova G.T.
Rofeev M.Sh.
Isometdinova Z.S.
Nazarova Z.Sh.
Samarkand State Medical University, Samarkand, Uzbekistan
Republican Scientific Center of Emergency Medical Care, Samarkand, Uzbekistan
https://doi.org/10.5281/zenodo.15203233
Objective:
To assess the potential of major risk factors ( RF ) in patients with AMI/ACS
(acute myocardial infarction/acute coronary syndrome) using the population of one of the
districts of Samarkand aged 20-69 years as an example.
Material and methods
: The present study was based on the data of the cohort study
"Register of acute myocardial infarction and acute coronary syndrome in one of the districts of
Samarkand . ACS and AMI were studied among the permanent population of one of the districts
of Samarkand, the age of patients included in the study was 20-69 years (since the beginning of
July 2009). The average age of the entire group was 58.5 ± 8.8 years, men - 56.8 ± 9.6 years,
women - 61.6 ± 5.8 years. A total of 216 patients with AMI/ACS admitted to hospital over 9
months were identified. Among them, AMI was detected in 75 (34.7%) cases, ACS in 141
(65.3%) cases. The results showed that the frequency of AMI/ACS in men was 2 times higher
than in women. In women, no cases of AMI/ACS were observed in the initial six five-year
periods, while 30 (21.7%) cases of the pathology under study were detected in men during this
period. Risk factor ( RF ) analysis showed that 28.2% of patients were smokers, with smokers
occurring among men 5.5 times more often. Overweight (BMI) and/or obesity were observed
in 76.8% of patients, with equal frequency among men and women. In the age group of 45-49
years, the incidence of this RF (obesity grades 1-3) was highest in men (82%) and women
(93%) . Hypercholesterolemia (> 200 mg/ dL ) was detected in 75 (34.7%) patients, including
44 (31.9%) men and 31 (39.7%) women. Analysis of the prevalence of hypercholesterolemia
depending on age showed that the highest values of this indicator were observed among 60-64
year old men 11 (25.2%) and 65-69 year old women 12 (38.7%). Diabetes mellitus (DM) was
suffered by 60 (27.8%) patients, women 2 times more often - (39.7% and 21.0%, respectively).
Arterial hypertension (AH) was suffered by 77.3% of patients (72.5% of men and 85.9% of
women), analysis by AH degrees showed that 28 (12.9%) had AH degree II, 10 (4.6%) - stage
III. Anamnesis data showed that a burdened family history of coronary heart disease was
observed in 113 (52.3%) men and women. This indicator did not differ significantly between
men and women (50.7% and 55.1%, respectively). In the group as a whole, 87 patients (40.2%)
had suffered AMI in the past, including 58 (42.0%) men and 29 (37.2%) women, stable angina
pectoris was suffered equally by men and women (66.6% and 73.0%, respectively
).
Conclusions
: The study demonstrated the highest prevalence of AMI/ACS in the age
group of 65-69 years. At the same time, the potential of the underlying risk factors among men
and women with AMI/ACS had its own characteristics: BMI was most common in the age groups
of 45-49 years and 55-59 years, respectively, in men and women. Hypercholesterolemia and
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hypertension were more often observed among women, while smoking was more typical for
men.
Foydalanilgan adabiyotlar/Используемая литература/References:
1.
Muinova KK et al. The role of risk factors in the development of myocardial infarction in
young men depending on family history // Achievements of science and education. - 2019. - No.
11 (52). - P. 70-74.
2.
Madjidova GT, Sunnatova GI, Hamidov NS CLINICAL AND HEMODYNAMIC CONDITIONS
AND HEART NATRIURETIC PEPTIDES IN THE BLOOD PLASMA OF PATIENTS WITH
HYPERTROPHIC CARDIOMYOPATHY //Eurasian Journal of Medical and Natural Sciences. –
2022. – T. 2. – No. 5. – pp. 211-219.
3.
Madjidova GT, Sunnatova GI, Usarov SA ABOUT THE SYSTEM OF TREATMENT OF
PATIENTS WITH ACUTE CORONARY SYNDROME //Eurasian Journal of Medical and Natural
Sciences. – 2022. – T. 2. – No. 5. – pp. 197-204.
4.
Alisherovna SN et al. Course of Myocardial Infarction in Young Women //Eurasian
Medical Research Periodical. – 2022. – T. 7. – S. 106 -111.
