COMPARATIVE FREQUENCY OF PREVALENCE OF INDIVIDUAL FORMS OF CONGENITAL CURVATURES OF THE GENITAL PENIS IN CHILDREN OF NAMANGAN

Annotasiya

Hypospadias as a disease was first described by Galen. However, hypospadias remains the most important medical and medical - social problem today throughout the world.

Manba turi: Konferentsiyalar
Yildan beri qamrab olingan yillar 2022
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Chiqarish:
57-59
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Кўчирилди

Кўчирилганлиги хақида маълумот йук.
Ulashish
Mamasaliev , N., Nurmatov , E., Alimov , M., Mamasaliev , Z., & Qurbonova , R. (2025). COMPARATIVE FREQUENCY OF PREVALENCE OF INDIVIDUAL FORMS OF CONGENITAL CURVATURES OF THE GENITAL PENIS IN CHILDREN OF NAMANGAN. Теоретические аспекты становления педагогических наук, 4(6), 57–59. Retrieved from https://inlibrary.uz/index.php/tafps/article/view/78084
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Annotasiya

Hypospadias as a disease was first described by Galen. However, hypospadias remains the most important medical and medical - social problem today throughout the world.


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THEORETICAL ASPECTS IN THE FORMATION OF

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COMPARATIVE FREQUENCY OF PREVALENCE OF INDIVIDUAL

FORMS OF CONGENITAL CURVATURES OF THE GENITAL PENIS IN

CHILDREN OF NAMANGAN

Mamasaliev N.S.

Nurmatov E.Kh.

Alimov M.M.

Mamasaliev Z.N.

Qurbonova R.R.

Andijan State Medical Institute, Uzbekistan

https://doi.org/10.5281/zenodo.15130925

Relevance.

Hypospadias as a disease was first described by Galen.

However, hypospadias remains the most important medical and medical - social
problem today throughout the world.

The medical and social significance of hypospadias is due to its high

prevalence, the tendency to a constant increase in the number of patients -
children, high disability due to complications and great economic damage.

In recent years, special attention has been paid to the issues of

epidemiology and prevention of hypospadias. This is due to the fact that despite
the large number of proposed methods of surgical correction, the treatment of
hypospadias still remains one of the most difficult problems in pediatric urology
due to the high percentage of complications.

Treatment of hypospadias is not only a complex, but also not fully resolved

problem. Therefore, the frequency of births of children with various forms of
hypospadias and the high percentage of postoperative complications, which,
according to modern researchers, reach 50%, continues to increase.

In this regard, the search for and study of safe and highly effective screening

(epidemiological innovative approaches) methods for early pre-nosological
prevention and treatment of hypospadias is a pressing problem for medical
science and practical healthcare.

The aim of the study:

to study the prevalence, improve the effectiveness of

prevention and surgical treatment of hypospadias based on our own innovative
developments in children of the Fergana Valley.

The object of the study

was 914 children with hypospadias from the

Fergana Valley (202 in the Andijan region, 467 in the Namangan region and 245
in the Fergana region) aged 0–18 years.

The subjects of the study

were venous and capillary blood, urine, analysis

of subjective and objective data, assessment of risk factors, materials, digital


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rectal examination of the prostate gland, data from drug therapy and surgical
treatment, as well as endoscopic and urodynamic equipment.

Research methods.

To achieve the goal of the dissertation and fulfill the

set

tasks,

subjective,

physical,

survey,

clinical,

biochemical,

pharmacoepidemiological, instrumental, special (digital rectal, echographic,
transrectal ultrasound, uroflowmetric, urethrocystoscopic, surgical) and
statistical methods were used.

Results of the study:

the presented results of the analysis of the obtained

results on the comparative frequency of prevalence of individual forms of
congenital curvature of the penis (CCP) in children of Namangan. It is noted that
CCP and CCp in the age group of children 0-18 years are observed with a
prevalence rate of 43.9% and 19.5% (P < 0.01), respectively. Depending on age,
their detection rates varied by up to 44% and 50% (P< 0.05) and were
determined at the following levels: at 0–1 years by 5.6% and 12.5% (P< 0.01), at
2–4 years by 50.0% and 50.0%, at 5–9 years by 27.8% and 25.0% (P> 0.05), at
10–14 years by 11.1% and 12.5% (P> 0.05), at 15–18 by 5.6% and 0.0% (P<
0.01). Other forms of HIV, HIVDSU and Peno TPPF in individual age groups of the
studied population were characterized by the following prevalence,
respectively: at 0-1 years by 14.3% and 0.0% (P< 0.01), at 2-4 years by 42.9%
and 50.0% (P< 0.05), at 5-9 years by 28.6% and 37.5% (P< 0.05), at 10-14 years
by 14.3% and 12.0% (P> 0.05), at 15-18 years by 17.1% and 19.5% (P> 0.05).

In general, summarizing the noted epidemiological trends, it can be

concluded that the prevalence of HIV in the population of children in Namangan,
depending on age, is noted with a difference of 26.9%. The highest detection rate
is observed at the age of 2-4 years (48.8%) and 5-9 years (29.3%). Significantly
low prevalence rates are observed at the age of 0-1 years 7.3%, 10-14 years
12.2% and 15-18 years 2.4% [Хи2 = 3.052; Df = 12; P> 0.05]. Taking these
characteristics into account is important when planning and implementing
prognostic and preventive programs for HIV in children in this region.

Literatures:

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methods and major patterns in GloBocan 2012. Int J Cancer, 2015. 136: E 359.
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2013. 16: 254.
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Gorduza DB, Gay GL, de Mattos E Silva E, et al. Does androgen stimulation

prior to hypospadias surgery increase the rate of heating complications – A
preliminary report. J Pediatr Urol 2011; 7: 158 – 61.
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Haid, B., et al. Penile appearance after hypospadias earrection from a

parent`s point of view: Comparison of the hypospadias objective penile
evaluation score and parents penile perception score. J Pediatr Urol. 2016. 12:
33e1.

Bibliografik manbalar

Гарманова Т.Н. Итальянские каникулы детских урологов // Дайдонет Урологии. Специальный выпуск. – 2013. - № 3. – С. 16 – 23.

Текчюл С. Главное в детской урологии – создание и внедрение образовательных программ // Дайджет Урологии. Специальный выпуск. – 2013. - № 3. – С. 7 – 14.

Anderson, M., et al. Hypospadias repair with tubularized incised plate: Does the obstructive flow pattern resolve spontaneously ? J Pediatr Urol, 2011. 7: 441.

Alexander. D.D. et al. Meta – Analysis of Long Chain Omega – 3 Polyunsaturated Fatty Acids (L Comega – 3 PUFA) and Prostate Cancer. Nutr CanCer. 2015. 67: 543.

Adams, J. et al. Reconstructive surgery for hypospadias: A systematic review of long – term patient satisfaction with cosmetic outcomes. Indian J Urol, 2016. 32:93.

Basros AN, Oliveira LR, Ferrarez CE, et al. Structural study of prepuce in hypospadias does topical treatment with testosterone produse alterations in prepuce vascularization ? J Urol 2011: 185: 2474 – 8.

Blanc – Lapierre, A. et al. Metabolic syndrome and prostate cancer risk a population – based casecontrol study in Montreal. Canada. BMC Public Health. 2015. 15: 913.

Breslow, N. et al. Latent carcinoza of prostate at outopsy in seven areas. The International Agency for Research on Cancer, Lyons, France. Int J Cancer, 1977.20: 680.

Chen, P., et al. Lycopene and rick of Prostate Cacer: A Systematic Review and Meta – Analysis Medicine (Baltimore). 2016. 94: e 1260.

Davies, N.M., et al. The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20.214 controls from the Practical Consortium. Cancer Causes Control. 2015.26: 1603.

Esposito, C., et al. Effect of metabolic syndrome and its components on prostate cancer risk: metaannalysis. J Endocrinol Invest. 2013.36:132.

Ferlay, J., et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GloBocan 2012. Int J Cancer, 2015. 136: E 359.

Freedland, S.J., et al. Statin use and risk of prostate cancer and high – grade prostate cancer: results from the REDUGE study. Prostate Cancer Prostatie Dis. 2013. 16: 254.

Gorduza DB, Gay GL, de Mattos E Silva E, et al. Does androgen stimulation prior to hypospadias surgery increase the rate of heating complications – A preliminary report. J Pediatr Urol 2011; 7: 158 – 61.

Haid, B., et al. Penile appearance after hypospadias earrection from a parent`s point of view: Comparison of the hypospadias objective penile evaluation score and parents penile perception score. J Pediatr Urol. 2016. 12: 33e1.