The American Journal of Medical Sciences and Pharmaceutical Research
36
https://www.theamericanjournals.com/index.php/tajmspr
TYPE
Original Research
PAGE NO.
36-38
10.37547/tajmspr/Volume07Issue05-07
OPEN ACCESS
SUBMITED
23 March 2025
ACCEPTED
19 April 2025
PUBLISHED
21 May 2025
VOLUME
Vol.07 Issue05 2025
CITATION
Ozodbekova Sitora, & Tashmatova Gulnoza. (2025). The impact of
breastfeeding on the development of allergic diseases in children. The
American Journal of Medical Sciences and Pharmaceutical Research, 7(05),
36
–
https://doi.org/10.37547/tajmspr/Volume07Issue05-07
COPYRIGHT
© 2025 Original content from this work may be used under the terms
of the creative commons attributes 4.0 License.
The impact of
breastfeeding on the
development of allergic
diseases in children
Ozodbekova Sitora
Medical School Student, Kimyo International University in Tashkent,
Tashkent, Uzbekistan
Tashmatova Gulnoza
Associate of Professor, PhD, Department of children’s diseases of
Tashkent medical academy, Tashkent, Uzbekistan
Abstract:
A study conducted from January 2024 to
January 2025 at the Tashkent Medical Academy and the
44th Family Polyclinic aimed to assess the impact of
breastfeeding on the risk of allergic diseases in children
and the mechanisms of its protective effects. A total of
187 children aged 0 to 3 years participated in the study.
The primary assessment method was a survey of
mothers, along with an analysis of clinical data,
including skin manifestations, respiratory symptoms,
and food intolerance. Children with identified
neurological disorders, congenital anomalies, and
severe somatic diseases were excluded from the study.
The results showed that breastfeeding for six months or
more significantly reduces the risk of developing
allergies (p<0.05). The prevalence of atopic dermatitis
among breastfed children was 12.4%, whereas among
formula-fed children, it reached 34.7%. A similar trend
was observed for respiratory allergies: 9.8% in breastfed
children versus 27.3% in formula-fed children. A
correlation was found between the duration of
breastfeeding and a reduction in skin allergies (r=-0.42,
p<0.01) as well as food intolerance (r=-0.36, p<0.05).
Additionally, children who were breastfed for more than
12 months had lower IgE levels (p<0.05), indicating a
stronger immune defense.Conclusion. Breastfeeding,
particularly for six months or longer, has a pronounced
protective effect, reducing the risk of allergic diseases,
including skin, respiratory, and food allergies. These
findings
confirm
the
importance
of
natural
breastfeeding as an effective allergy prevention strategy
in early childhood.
The American Journal of Medical Sciences and Pharmaceutical Research
37
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The American Journal of Medical Sciences and Pharmaceutical Research
Keywords:
Breastfeeding, allergic diseases, survey,
immune protection.
Introduction:
The health of mothers and children, as
well as the improvement of pediatric care worldwide,
remains a top priority in healthcare. It is recognized
that maternal and child health indicators should be
used as criteria for assessing a society’s socio
-
economic development. A multifactorial approach is
crucial, focusing on proper nutrition, physical
development, intellectual potential, and overall health
throughout life [1,2,5].
Breastfeeding is an integral part of the reproductive
cycle, a cornerstone of child survival, nutrition, and
development, and a determinant of maternal health in
both the short and long term. It is also one of the
fundamental components of neonatal care and quality
medical assistance[3,4]. Children who are exclusively
breastfed for the first six months have lower rates of
infectious and non-infectious diseases, lower mortality
rates, and higher intelligence levels compared to those
who receive breast milk for a shorter duration or not
at all. These health disparities persist throughout life
[6,7].
To assess the impact of breastfeeding on the risk of
developing allergic diseases in children and to
investigate its protective mechanisms.
METHODS
The study was conducted from January 2024 to
January 2025 at the Tashkent Medical Academy and
the 44th Family Polyclinic. A total of 187 children aged
0 to 3 years participated. The study utilized a survey
method for breastfeeding mothers to evaluate the
influence of breastfeeding on allergy development.
Children’s allergic conditions were assessed based on
clinical data, history of diathesis, and anamnesis.
Additionally, an allergy status assessment scale was
used to measure the severity of skin manifestations,
frequency of respiratory symptoms, and presence of
food intolerance.
Children with diagnosed neurological disorders,
congenital anomalies, and severe somatic diseases
that could influence allergic pathology development
were excluded from the study.
RESULTS AND DISCUSSION
According to the survey data, 132 children (70.6%)
were exclusively breastfed for the first six months,
while 55 children (29.4%) received mixed or formula
feeding. Among exclusively breastfed children, allergic
diseases were recorded in 14.4% of cases. In contrast,
the prevalence was 36.3% in the mixed or formula-fed
group. The frequency of diathesis among breastfed
children was 10.6%, compared to 28.1% in non-
breastfed children. Respiratory allergic manifestations
(such as bronchial asthma and allergic rhinitis) were
found in 8.3% of breastfed children and 22.7% of
formula-fed children. Food intolerance was observed in
12.1% of breastfed children and in 31.8% of formula-fed
children. Data analysis indicated that children who were
exclusively breastfed for the first six months had a
significantly lower risk of developing allergic diseases
than those who received mixed or formula feeding
(p<0.05). The prevalence of atopic dermatitis among
exclusively breastfed children was 12.4%, while it was
34.7% among formula-fed children. The development of
respiratory allergic symptoms (allergic rhinitis, bronchial
asthma) was observed in 9.8% of breastfed children and
in 27.3% of formula-fed children. It was found that the
duration of breastfeeding correlated with a lower
frequency of skin allergy manifestations (r=-0.42,
p<0.01) and a reduction in cases of food intolerance (r=-
0.36, p<0.05). Further analysis showed that children
who were breastfed for more than 12 months had
significantly lower serum IgE levels (p<0.05), confirming
the protective effect of breastfeeding against
sensitization.
CONCLUSION
The study results confirm that breastfeeding has a
protective effect against the development of allergic
diseases in children. Exclusively breastfed children
during the first six months of life had lower rates of skin
allergies, respiratory diseases, and food intolerance.
These findings emphasize the importance of promoting
breastfeeding as a strategy for preventing allergic
diseases in young children.
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The American Journal of Medical Sciences and Pharmaceutical Research
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