Role And Significance Of Kisspeptin In The Female Reproductive System

HAC
inLibrary
Google Scholar
doi
 
CC BY f
31-38
5
1
To share
F.A.Xaydarova, ., N.M. Baqoyeva , ., & Y.X.Turakulov , . (2021). Role And Significance Of Kisspeptin In The Female Reproductive System. The American Journal of Medical Sciences and Pharmaceutical Research, 3(04), 31–38. https://doi.org/10.37547/TAJMSPR/Volume03Issue04-04
Crossref
Сrossref
Scopus
Scopus

Abstract

The functioning of the female reproductive system depends on the proper development and regulation of the hypothalamic-pituitary-ovarian axis. It is based on the secretion of GnRH, which stimulates the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). There have been many studies investigating the factors that regulate the secretion of gonadotropins. In recent years, the significance and role of kisspeptin and its receptor has aroused interest. This review will provide data from foreign studies and literature on the role of kisspeptin in the regulation of the female reproductive system.

Similar Articles

References

JH Lee, ME Miele, DJ Hicks et al., “KiSS-1, a novel human malignant melanoma metastasis-suppressor gene,” Journal of the National Cancer Institute, vol. 88, no. 23, pp. 1731-1737, 1996.

Y. Horikoshi, H. Matsumoto, Y. Takatsu et al., “Dramatic elevation of plasma metastin concentrations in human pregnancy: metastin as a novel placenta-derived hormone in humans,” Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 2, pp. 914-919, 2003.

Mead EJ, Maguire JJ, Kuc RE, Davenport AP Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. J. Pharmacol. 2007; 151 (8): 1143-53.

Zeydabadi Nejad S., et al. “The Role of Kisspeptin in Female Reproduction”. International Journal of Endocrinology and Metabolism 15.3 (2017): e44337.

Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice / D. Grattan, C. Jasoni, X. Liu [et al.] // Endocrinology. - 2007. - Vol. 148, N 9. - P.4344–4351. doi: 10.1210 / en.2007-0403.

Kokay, I. Identification of prolactin-sensitive GABA and kisspeptin neurons in regions of the rat hypothalamus involved in the control of fertility / I. Kokay, S. Petersen, D. Grattan // Endocrinology. - 2011. - Vol.152, N 2. - P.526–535. doi: 10.1210 / en.2010-0668.

Hyperprolactinemia-induced ovarian acyclicity is reversed by kisspeptin administration / C. Sonigo, J. Bouilly, N. Carré [et al.] // J. Clin. Investig. 2012. - Vol. 122, N 10. - P.3791-3795. doi: 10.1172 / jci63937.

The GPR54 gene as a regulator of puberty / S. Seminara, S. Messager, E. Chatzidaki [et al.] // New Engl. J. Med. - 2003. - Vol.349. - P.1614-1627. doi: 10.1056 / NEJMoa035322.

Silveira, L. Kisspeptin and clinical disorders / L. Silveira, A. Latronico, S. Seminara // Adv. Exp. Med. Biol. - 2013. - Vol.784. - P.187-199. doi: 10.1007 / 978-1- 4614-6199-9_9.

Partsch, C. Management and outcome of central precocious puberty / C. Partsch, S. Heger, W. Sippell // Clin. Endocrinol. - 2002. - Vol.56. - P.129-148.

A GPR54-activating mutation in a patient with central precocious puberty / M. Teles, S. Bianco, V. Brito [et al.] // New England J. Med. - 2008. - Vol.358. - P.709-715. doi: 10.1056 / NEJMoa073443.

KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation / S. Bianco, L. Vandepas, M. Correa-Medina [et al.] // Endocrinology. - 2011. - Vol. - P.152: 1616-1626. doi: 10.1210 / en.2010-0903.

Kisspeptin serum levels in girls with central precocious puberty / L. de Vries, B. Shtaif, M. Phillip, G. Gat-Yablonski // Clin. endocrinol. - 2009. - Vol.71. - P.524-528.doi: 10.1111 / j.1365-2265.2009.03575.x

Lee, P. Puberty and its disorders / P. Lee, C. Houk // Pediatric Endocrinology / ed. F. Liftshitz. - N.-Y .: Informa Healthcare Inc., 2000. - P.274-290.

Katulski K, Podfigurna A, Czyzyk A, Meczekalski B, Genazzani AD. Kisspeptin and LH pulsatile temporal coupling in PCOS patients. Endocrine. (2018) 61: 149-57. doi: 10.1007 / s12020-018-1609-1

Pielecka-Fortuna, J. Kisspeptin Acts Directly and Indirectly to Increase Gonadotropin-Releasing Hormone Neuron Activity and Its Effects Are Modulated by Estradiol / J Pielecka-Fortuna, Z. Chu, S. Moenter // Endocrinology. - 2008. - Vol. 149, N 4. - P. 1979-1986. doi: 10.1210 / en.2007-1365.

Increased plasma metastin levels in adolescent women with polycystic ovary syndrome / X. Chen, Y. Mo, L. Li [et al.] // Eur. J. Obstet. Gynecol. Reprod. Biol. - 2010. - Vol. 149, N 1. - P.72-76. doi: 10.1016 / j.ejogrb.2009.11.018.

Genazzani A. D., Gastaldi M., Petraglia F., Battaglia C., Surico N., Volpe A. et al. Naltrexone administration modulates the neuroendocrine control of luteinizing hormone secretion in hypothalamic amenorrhoea. Hum. Reprod. 1995; 10(11): 2868–71.

Guran T., Tolhurst G., Bereket A., Rocha N., Porter K., Turan S. et al. Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor. J. Clin. Endocrinol. Metab. 2009; 94(10): 3633–9.

Navarro V. M., Gottsch M. L., Chavkin C., Okamura H., Clifton D. K., Steiner R. A. Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. J. Neurosci. 2009; 29(38): 11859–66.

Topaloglu A. K., Reimann F., Guclu M., Yalin A. S., Kotan L. D., Porter K. M. et al. TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. Nat. Genet. 2009; 41(3): 354–8.

Navarro V. M. Interactions between kisspeptins and neurokinin B. Adv. Exp. Med. Biol. 2013; 784: 325–47.

Maalhagh M., Jahromi A. S., Yusefi A., Razeghi A., Zabetiyan H., Karami M. Y. et al. Effects of prepubertal acute immobilization stress on serum kisspeptin level and testis histology in rats. Pak. J. Biol. Sci. 2016; 19(1): 43–8.

Hirano T., Kobayashi Y., Omotehara T., Tatsumi A., Hashimoto R., Umemura Y. et al. Unpredictable chronic stress-induced reproductive suppression associated with the decrease of kisspeptin immunoreactivity in male mice. J. Vet. Med. Sci. 2014; 76(9): 1201–8.

inLibrary — это научная электронная библиотека inConference - научно-практические конференции inScience - Журнал Общество и инновации UACD - Антикоррупционный дайджест Узбекистана UZDA - Ассоциации стоматологов Узбекистана АСТ - Архитектура, строительство, транспорт Open Journal System - Престиж вашего журнала в международных базах данных inDesigner - Разработка сайта - создание сайтов под ключ в веб студии Iqtisodiy taraqqiyot va tahlil - ilmiy elektron jurnali yuridik va jismoniy shaxslarning in-Academy - Innovative Academy RSC MENC LEGIS - Адвокатское бюро SPORT-SCIENCE - Актуальные проблемы спортивной науки GLOTEC - Внедрение цифровых технологий в организации MuviPoisk - Смотрите фильмы онлайн, большая коллекция, новинки кинопроката Megatorg - Доска объявлений Megatorg.net: сайт бесплатных частных объявлений Skinormil - Космецевтика активного действия Pils - Мультибрендовый онлайн шоп METAMED - Фармацевтическая компания с полным спектром услуг Dexaflu - от симптомов гриппа и простуды SMARTY - Увеличение продаж вашей компании ELECARS - Электромобили в Ташкенте, Узбекистане CHINA MOTORS - Купи автомобиль своей мечты! PROKAT24 - Прокат и аренда строительных инструментов