LABORATORY CHARACTERISTICS OF PATIENTS WITH DIABETES MELLITUS DEPENDING ON THE RISK OF CONTRAST INDUCED AKI

HAC
inLibrary
Google Scholar
doi
 
CC BY f
32-36
3
1
To share
Muminov Sh.K., ., & Nigmonov B.B., . (2023). LABORATORY CHARACTERISTICS OF PATIENTS WITH DIABETES MELLITUS DEPENDING ON THE RISK OF CONTRAST INDUCED AKI. The American Journal of Medical Sciences and Pharmaceutical Research, 5(01), 32–36. https://doi.org/10.37547/TAJMSPR/Volume05Issue01-04
Crossref
Сrossref
Scopus
Scopus

Abstract

Aim of the work: assessment of laboratory characteristics in patients with type 2 diabetes, depending on the risk of developing CI-AKI.

Materials and methods: The study included 56 patients with type 2 diabetes, the average age of the patients was 58 years, the CG consisted of 20 healthy volunteers. In most patients, the reason for which the endovascular radiopaque procedure (EVRCP) was performed was associated with atherosclerotic lesions: coronary artery disease, chronic lower limb ischemia (CLLI), atherosclerosis of the brachiocephalic arteries (BCA). EVRCP was performed on the vessels of the coronary basin, BCA, abdominal aorta and its branches, lower extremities. A retrospective analysis included a comparative analysis of two groups of patients with type 2 diabetes who underwent EVRCP: 29 patients who developed CI-AKI (CI-AKI+ group) and 27 patients in whom the post-procedure period was uneventful.

Results: The CI-AKI+ and CI-AKI- groups did not differ in nosological distribution: in both groups, half of the patients with EVRCP were performed due to the presence of coronary pathology (51.72% and 48.15%, respectively), the rest in patients it was comparable for CCI and CVD (27.59% and 20.69% in the CI-AKI+ group and 25.93% each in the CI-AKI- group).

Conclusion: Thus, based on the results of this study, it was possible to identify risk factors for the development of CI-AKI in patients with DM in the post-procedure period and to develop a scale that allows identifying DM patients predisposed to the development of CI-AKI as a hospital complication of endovascular interventional procedures, which is especially often observed in patients with DM.

 

Similar Articles

References

Li Y, Ren K. The Mechanism of Contrast-Induced Acute Kidney Injury and Its Association with Diabetes Mellitus. Contrast Media Mol Imaging. 2020 Jun 23;2020:3295176. doi: 10.1155/2020/3295176.

Marenzi G, Lauri G, Assanelli E, Campodonico J, De Metrio M, Marana I, Grazi M, Veglia F, Bartorelli AL. Contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarction. J Am Coll Cardiol. 2004 Nov 2;44(9):1780-5. doi: 10.1016/j.jacc.2004.07.043.

van der Molen A. J., Reimer P., Dekkers I. A., et al. Post-contrast acute kidney injury—part 1: definition, clinical features, incidence, role of contrast medium and risk factors. European Radiology. 2018;28(7):2815–2855. doi: 10.1007/s00330-017-5246-5.

Makris K, Spanou L. Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes. Clin Biochem Rev. 2016 May;37(2):85-98.

Stacul F., van der Molen A. J., van der Molen A. J., et al. Contrast induced nephropathy: updated ESUR contrast media safety committee guidelines. European Radiology. 2011;21(12):2527–2541. doi: 10.1007/s00330-011-2225-0.

Келлум Д.А. Острое почечное повреждение. Клинические практические рекомендации KDIGO (основные положения) / Д.А. Келлум, Н. Лемер // Нефрология и диализ. – 2012. – Т. 14, № 2. – С. 86–94.

Hose E. A., Kellum J. A., Selby N. M., et al. Global epidemiology and outcomes of acute kidney injury. Nature Reviews Nephrology. 2018;14(10):607–625. doi: 10.1038/s41581-018-0052-0.

Morabito S., Pistolesi V., Benedetti G., et al. Incidence of contrast-induced acute kidney injury associated with diagnostic or interventional coronary angiography. Journal of Nephrology. 2012;25(6) doi: 10.5301/jn.5000101.

Katzberg R. W., Newhouse J. H. Intravenous contrast medium-induced nephrotoxicity: is the medical risk really as great as we have come to believe? Radiology. 2010;256(1):21–28. doi: 10.1148/radiol.10092000.

Shiyovich A, Skalsky K, Steinmetz T, Ovdat T, Eisen A, Samara A, Beigel R, Gleitman S, Kornowski R, Orvin K. Acute Kidney Injury Following Admission with Acute Coronary Syndrome: The Role of Diabetes Mellitus. J Clin Med. 2021 Oct 25;10(21):4931. doi: 10.3390/jcm10214931. PMID: 34768451;

Liu Y, Liang X, Xin S, Liu J, Sun G, Chen S, Cen X, Dai X, He Y, Song F, Liang Y, Hu Y, Zhou Y, Chen Z, Tan N, Chen J. Risk factors for contrast-induced acute kidney injury (CI-AKI): protocol for systematic review and meta-analysis. BMJ Open. 2019 Aug 15;9(8):e030048. doi: 10.1136/bmjopen-2019-030048.

Thomas MC, Brownlee M, Susztak K, Sharma K, Jandeleit-Dahm KA, Zoungas S, Rossing P, Groop PH, Cooper ME. Diabetic kidney disease. Nat Rev Dis Primers. 2015 Jul 30;1:15018. doi: 10.1038/nrdp.2015.18.

inLibrary — это научная электронная библиотека inConference - научно-практические конференции inScience - Журнал Общество и инновации UACD - Антикоррупционный дайджест Узбекистана UZDA - Ассоциации стоматологов Узбекистана АСТ - Архитектура, строительство, транспорт Open Journal System - Престиж вашего журнала в международных базах данных inDesigner - Разработка сайта - создание сайтов под ключ в веб студии Iqtisodiy taraqqiyot va tahlil - ilmiy elektron jurnali yuridik va jismoniy shaxslarning in-Academy - Innovative Academy RSC MENC LEGIS - Адвокатское бюро SPORT-SCIENCE - Актуальные проблемы спортивной науки GLOTEC - Внедрение цифровых технологий в организации MuviPoisk - Смотрите фильмы онлайн, большая коллекция, новинки кинопроката Megatorg - Доска объявлений Megatorg.net: сайт бесплатных частных объявлений Skinormil - Космецевтика активного действия Pils - Мультибрендовый онлайн шоп METAMED - Фармацевтическая компания с полным спектром услуг Dexaflu - от симптомов гриппа и простуды SMARTY - Увеличение продаж вашей компании ELECARS - Электромобили в Ташкенте, Узбекистане CHINA MOTORS - Купи автомобиль своей мечты! PROKAT24 - Прокат и аренда строительных инструментов