INFLUENCE OF SNAKE (NAJA NAJA) VENOM ON DNA DAMAGE IN ALBINO RATS
Keywords:
Abstract
Snake venom contains a complex mixture of bioactive components that can have profound effects on various physiological processes. The aim of this study was to investigate the influence of snake (Naja naja) venom on DNA damage in albino rats. Albino rats were injected with a controlled dosage of Naja naja venom, and the extent of DNA damage was assessed using various molecular techniques. The results revealed a significant increase in DNA damage in the venom-injected rats compared to the control group. The observed DNA damage included single-strand breaks, double-strand breaks, and oxidative damage. The findings highlight the potential genotoxic effects of snake venom on DNA integrity and suggest the importance of further research to understand the underlying mechanisms and develop appropriate therapeutic interventions.
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References
Asselta R and Peyvandi F (2009), Factor Vdeficiency SeminThrombHemost., Vol. 35,No. 4, pp. 382-9.
Bahman Maroufi, Kaboudanian SussanArdestani, Amina Kariminia, HussainNaderimanesh (2005) “The effect of vitaminE on splenocytes apoptosis of gammairradiated BALB/C mice”, Iranian Journal ofAllergy , Asthma and Immunology., Vol. 35,No. 1, pp. 77-82.
Bailey P Wilce (2001), “J Venom as a sourceof useful biologically active molecules”,Emergency Medicine, Vol. 13, pp. 28-36.
Brachet J and Jeener R (1944),“Macromolecular Cytoplasmic ParticlesRich in Pentose Nucleic Acid. I. Generalproperties Relation to Hydrolase, Hormonesand Structural Proteins”, Enzymologia., Vol.1, pp. 196-212.
Gillo L (1966), “Biochemistry of snakevenom”, Toxicon. Ann. Soc Roy Sci MedNat Bruxelles, Vol. 19, pp. 121.
Gosselin L, Bacq C M, Gosselin F C, ReyC, Kozma S and Osterieth P M (1977),“Phospholipids of the Milk-fat-globuleMembrane and the Mouse Mammary Tumorvirus isolated from the milk of infected mice”,Biochem. Soc. Trans., Vol. 5, pp. 142-144.
Hantgan P (2005), “Snake venom revealsclues about heart drug”, Baptist Medical.,Vol. 1, pp. 1-3.
Holley R W (1968), “Biochemistry of snakevenom”, Toxicon. Progr.Nucleic Acids Res,Vol. 8, pp. 37.
