On the basis of comparative studies of physicochemical parameters of the oral fluid in patients with normal blood pressure, pre-hypertension, and clinically verified arterial hypertension, a violation of physicochemical parameters of the oral fluid has been identified: reduced rate of salivation, decrease in pH, increase in viscosity and surface tension, and reduced buffering capacity to neutralize acids and bases associated with high blood pressure. Decreased functional activity of the salivary glands may be a potential biomarker of hypertension. To assess their diagnostic value, the physicochemical parameters of oral fluid in the diagnosis of arterial hypertension require further research.
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