Determine the role of studying socio-biological factors and obstetric-gynecological history in predicting and early diagnosis of the threat of termination in the first trimester of pregnancy. We analyzed 210 case histories of patients who were treated in the gynecological department of the Perinatal Center in Bukhara and were observed in antenatal clinics No. 6 and No. 11 of the same city for the period of 2019. All pregnant women were divided into two groups. The main I-group consisted of 110 women, whose pregnancies with the threat of termination with clinical symptoms - pain in the lower abdomen with the onset of the 1st trimester at gestation periods from 5 to 12 weeks. The control group included 100 patients with the physiological course of pregnancy II – group.
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