Infectious diseases are one of the most serious problems because they are the most widespread and the leading cause of death. Although significant advances have been made over the past decades in addressing this problem, this statement is still true today. Sepsis is the leading cause of death in critical care patients. It develops in 750000 people each year and more than 210000 of them die. Progress in the study of the pathophysiology and genetic basis of the individual response to sepsis has changed the common understanding of this syndrome, and some therapeutic interventions used in recent years have demonstrated efficacy; however, the problem of intensive care is still quite acute and requires further research.
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