Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease primarily affecting the axial skeleton. Recent research has shed light on a concerning association between AS and venous thromboembolic disease (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE). This paper explores the emerging evidence elucidating the heightened risk of VTE in patients with AS, emphasizing the underlying mechanisms and clinical implications. Factors such as chronic inflammation, endothelial dysfunction, and immobility contribute to the prothrombotic state observed in AS patients. Understanding this association is crucial for timely recognition, risk stratification, and implementation of preventive measures in clinical practice.
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