UNRAVELING THE EVOLUTION OF PAIN SENSITIVITY: LONG-TERM INSIGHTS FROM AN ANIMAL MODEL OF SOCIAL ANXIETY

HAC
inLibrary
Google Scholar
doi
 
CC BY f
17-21
0
1
To share
Veronica Francia, . (2023). UNRAVELING THE EVOLUTION OF PAIN SENSITIVITY: LONG-TERM INSIGHTS FROM AN ANIMAL MODEL OF SOCIAL ANXIETY. The American Journal of Veterinary Sciences and Wildlife Discovery, 5(04), 17–21. https://doi.org/10.37547/tajvswd/Volume05Issue04-05
Crossref
Сrossref
Scopus
Scopus

Abstract

This study delves into the long-term alterations in pain sensitivity within an animal model of social anxiety. Social anxiety is a prevalent psychiatric disorder that profoundly affects an individual's emotional and social well-being. The investigation utilized a well-established animal model to explore the potential connection between social anxiety and pain perception. Through a series of behavioral tests and neurobiological assessments, the study reveals the enduring changes in pain sensitivity over time, shedding light on the intricate interplay between social anxiety and pain processing. The findings offer valuable insights into the evolutionary aspects of pain sensitivity and provide a foundation for further research in understanding the complex relationship between social anxiety and pain perception in humans.

References

Anisman, H.; Merali, Z.; Stead, J.D. Experiential and genetic contributions to depressive- and anxiety-like disorders: Clinical and experimental studies. Neurosci. Biobehav. Rev. 2008, 32, 1185–1206. [Google Scholar] [CrossRef]

Cirulli, F.; Alleva, E. The NGF saga: From animal models of psychosocial stress to stress-related psychopathology. Front Neuroendocrinol. 2009, 30, 379–395. [Google Scholar]

Cryan, J.F.; Holmes, A. The ascent of mouse: Advances in modelling human depression and anxiety. Nat. Rev. Drug Discov. 2005, 4, 775–790. [Google Scholar] [CrossRef]

Koolhaas, J.M.; de Boer, S.F.; Buwalda, B.; van Reenen, K. Individual variation in coping with stress: A multidimensional approach of ultimate and proximate mechanisms. Brain Behav. Evol. 2007, 70, 218–226. [Google Scholar] [CrossRef]

Miczek, K.A.; de Wit, H. Challenges for translational psychopharmacology research—Some basic principles. Psychopharmacology (Berl.) 2008, 199, 291–301. [Google Scholar] [CrossRef]

Koolhaas, J.M.; de Boer, S.F.; de Rutter, A.J.; Meerlo, P.; Sgoifo, A. Social stress in rats and mice. Acta Physiol. Scand Suppl. 1997, 640, 69–72. [Google Scholar]

Tamashiro, K.L.; Nguyen, M.M.; Sakai, R.R. Social stress: From rodents to primates. Front Neuroendocrinol. 2005, 26, 27–40. [Google Scholar] [CrossRef]

Willner, P. The validity of animal models of depression. Psychopharmacology (Berl.) 1984, 83, 1–16. [Google Scholar] [CrossRef]

Berry, A.; Bellisario, V.; Capoccia, S.; Tirassa, P.; Calza, A.; Alleva, E.; Cirulli, F. Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice. Psychoneuroendocrinology 2012, 37, 762–772. [Google Scholar] [CrossRef]

Kudryavtseva, N.N.; Bakshtanovskaya, I.V.; Koryakina, L.A. Social model of depression in mice of C57BL/6J strain. Pharmacol. Biochem. Behav. 1991, 38, 315–320. [Google Scholar] [CrossRef]

inLibrary — это научная электронная библиотека inConference - научно-практические конференции inScience - Журнал Общество и инновации UACD - Антикоррупционный дайджест Узбекистана UZDA - Ассоциации стоматологов Узбекистана АСТ - Архитектура, строительство, транспорт Open Journal System - Престиж вашего журнала в международных базах данных inDesigner - Разработка сайта - создание сайтов под ключ в веб студии Iqtisodiy taraqqiyot va tahlil - ilmiy elektron jurnali yuridik va jismoniy shaxslarning in-Academy - Innovative Academy RSC MENC LEGIS - Адвокатское бюро SPORT-SCIENCE - Актуальные проблемы спортивной науки GLOTEC - Внедрение цифровых технологий в организации MuviPoisk - Смотрите фильмы онлайн, большая коллекция, новинки кинопроката Megatorg - Доска объявлений Megatorg.net: сайт бесплатных частных объявлений Skinormil - Космецевтика активного действия Pils - Мультибрендовый онлайн шоп METAMED - Фармацевтическая компания с полным спектром услуг Dexaflu - от симптомов гриппа и простуды SMARTY - Увеличение продаж вашей компании ELECARS - Электромобили в Ташкенте, Узбекистане CHINA MOTORS - Купи автомобиль своей мечты! PROKAT24 - Прокат и аренда строительных инструментов