Authors

  • Rustamov Bakhtiyor Suvonkulovich
    Doctor of Philosophy ( PhD ), Samarkand State University of Veterinary Medicine, Animal Husbandry and Biotechnology, Uzbekistan
  • Khudoyorov Dilshod
    Master, Samarkand State University of Veterinary Medicine, Animal Husbandry and Biotechnology, Uzbekistan
  • Odinaev Otabek
    Student, Samarkand State University of Veterinary Medicine, Animal Husbandry and Biotechnology, Uzbekistan

DOI:

https://doi.org/10.37547/tajvswd/Volume06Issue03-06

Keywords:

Systematic position phenology range of the sheep gadfly

Abstract

The article summarizes the distribution of oestrose in sheep, epidemiological data and a review of the literature.


background image

THE USA JOURNALS

THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY
(ISSN

2689-0968)

VOLUME 06 ISSUE03

24

https://www.theamericanjournals.com/index.php/tajvswd

PUBLISHED DATE: - 21-06-2024

DOI: -

https://doi.org/10.37547/tajvswd/Volume06Issue03-06

PAGE NO.: - 24-28

ESTROSIS OF SHEEP AND DEVELOPMENT OF
MEASURES AND CONTROL (LITERATURE
REVIEW)

Rustamov Bakhtiyor Suvonkulovich

Doctor of Philosophy (PhD), Samarkand State University of Veterinary Medicine, Animal
Husbandry and Biotechnology, Uzbekistan

Khudoyorov Dilshod

Master, Samarkand State University of Veterinary Medicine, Animal Husbandry and

Biotechnology, Uzbekistan

Odinaev Otabek

Student, Samarkand State University of Veterinary Medicine, Animal Husbandry and

Biotechnology, Uzbekistan

INTRODUCTION

Extent of Oestrus ovis range and the need to ensure

veterinary well-being regarding estrosis have

necessitated a complex of fundamental and applied
research.
Scientists have carried out extensive research on

the biology, ecology, phenology and distribution of

estrosis pathogens in sheep (Beklemishev V.N.,
1951; Gan E.V., 1964; Domatsky V.N., 1988;

Shcherban N.F., 1971, 198 7 ; Ternovoy V.I., 1986;
Marchenko V.A., 1994, 1997; Sivkov G.S., 1995;

Migunov I.M., 1998, etc.).
The research results created the necessary

prerequisites for the development of effective
measures to combat the botfly.

To combat estrosis, drugs from different groups of

chemical compounds have been proposed,

ensuring high efficiency of therapeutic and
preventive measures.
The prospects of using the chemical method of

protecting animals from harmful arthropods are

emphasized. Currently, in the practice of
combating ectoparasites of farm animals, synthetic

pyrethroids, which are 4th generation pesticides
and are characterized by selective toxicity to

arthropods, the ability to rapidly biodegrade and
are harmless to warm-blooded animals, are

increasingly used.
It has been established that the long-term use of

RESEARCH ARTICLE

Open Access

Abstract


background image

THE USA JOURNALS

THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY
(ISSN

2689-0968)

VOLUME 06 ISSUE03

25

https://www.theamericanjournals.com/index.php/tajvswd

insecto-acaricides requires constant improvement
of the technology of their use due to the threat of

the formation of resistant races of insects. There is

a need for strict regulation, competent
toxicological analysis for the selection and use of

drugs that, against the background of pronounced
therapeutic and prophylactic effectiveness, would

meet the sanitary and hygienic requirements for
them.
Systematic

position,

biology,

phenology,

population ¬ecology, range of the sheep gadfly
Sheep botfly ( Oestrus ovis Line , 1864) belongs to

the class of insects In- secta , the order of Diptera
Diptera , the family of nasopharyngeal gadflies

Oestridae .
Adult O. ovis a small insect 9-12 mm long. The div

is covered with small hairs. The head is large, the

abdomen is short, oval. The head and dorsal surface

of the chest are inseparable, brown-gray in color,
the abdomen is yellowish-gray with small

checkerboard patterns (Gan E.I., 1953).
In the literature of recent decades there are

multiple reports ¬concerning the study of the

biology of the banded gadfly (Beklemishev N.D.,
1951; Blagoveshchensky D.I., 1937; Breev K.A.,

1975; Gan E.I., 1964; Grunin K. N., 1956; Dukalov I.
A., 1957; Kolomiets Yu. S., Alfimova A. V., 1956;

Shcherban N. F., 1968, 1971; I., 1971, 1972, 1986;

Semenov P. V., 1986; Marchenko V. A., 1985;
According to V.P. Tolokonnikov (1995), the flight of

the sheep gadfly in the Stavropol ¬Territory begins

in June and ends in the third ten days of October -
the first ten days of November.
In summer, males live 3-9 days, in autumn

somewhat longer. The life expectancy ¬of females

in summer is 15-20 , in autumn - up to 40 days
(Ternova V.I., 1995)
Fertilized females do not fly. Within 10-15 days,

¬larvae form in a queen-like receptacle. Adults do
not feed; they live off the nutrients accumulated in

the larval phase. Upon completion of the larval
maturation process, the females become active and

begin to fly. Female gadflies are viviparous; the

fertility of one female is about 700 larvae.

(Tolokonnikov V.P., 2005).
Insects lay larvae within 2-4 days. At one time, the

female injects 8-12 1st stage larvae into the nasal
cavity of the sheep.
Stage 1 larvae are localized on the inner surface of

the inferior turbinates, the nasal septum, and the
wall of the nasal cavity. The strong attachment of

the larvae to the nasal concha mucous membrane

is crucial for their survival and development. This
allows them to access a good source of nutrients

and oxygen, which are essential for their growth
and maturation. The larvae's ability to secure

themselves in this location demonstrates their
adaptability and evolutionary advantage in their

environment. The armament of larvae of the 2nd
and 3rd stages is weaker; they are localized in the

maxillary, frontal sinuses, and cavities of the horny
processes (Gan I.N., 1942).
During ontogenesis, the larvae molt twice in the

host's div. Larvae of the 1st ¬stage molt in the

nasal turbinates; they undergo the second molt in
the labyrinths of the ethmoid bone and frontal

sinuses (Krivko A. M., 1956).
In stage 3 larvae, the dorsal side of each segment

has pigmented transverse stripes of brown-black

color. During pupation ¬, the larvae shorten to 15
mm, the outer shell turns black, hardens, and turns

into a false cocoon (Ternova V.I., 1972).
Mature larvae of the 3rd stage migrate from the

frontal sinuses to the nasal ¬cavity and irritate the
mucous membrane, which causes reflex sneezing

in sheep, which contributes to the release of
parasites into the environment. The larvae

penetrate the soil to a depth of 1-5 cm. The pupal
phase is 14-16 days (Akbaev M. Sh., 2002).

The duration of development of larvae in the host’s

div in the ¬North Caucasus zone is 150-240 days

for autumn infection, 30-45 days for spring
infection (V.I. Ternovoy, 1985, 1995).
S.P.Kuklin, (1952), I.I.Klenin (1958), Ch.E.Rogers ,

F.W.Knapp (1973) noted that during the
adaptation process of 1st stage larvae of O. ovis In

the host organism, their mass death (up to 90%) is

observed in the first days after infection, and only


background image

THE USA JOURNALS

THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY
(ISSN

2689-0968)

VOLUME 06 ISSUE03

26

https://www.theamericanjournals.com/index.php/tajvswd

after 20-30 days the death of larvae decreases.
P.V. Semenov (1987) notes that the natural and

climatic conditions of the habitat of O. ovis affect
the amount of generation per year. In years with

one generation, the development of larvae in the
div of sheep lasts 8

11 months ¬; with two

generations, the duration of the development cycle
of larvae of the autumn generation is 8-10 months,

in the spring - 1-3.
A number of authors (Krivko A.M., 1956;

Spiryukhov I.A., Machulsky S.N., 1959; Kalkis Ya.I.,
1965; Manytskov A.Ya., 1969; Ponomarev I.A.,

1971; Mi ¬Gunov I.M., 1971; Kamarli A.P.,
Tuganbaev A.T., 1972; Shcherban N.F., 1976;

Sivkov G.S., 1981) established that the timing The
emergence of 3rd stage larvae for pupation

depends on the climatic conditions of the insect
habitat. In biotopes with the development of one

generation of the botfly, larvae pupate from April
to July. In zones of two generations, the larvae of

the first generation leave the host’s div in the

period from February-March to May-July, the

second - from July to September-October.
V. A. Marchenko (1985) reports that the

transformation of larvae into the 2nd stage occurs
in the fall, and into the 3rd stage in winter.
G.S. Sivkov (1979) noted in the metamorphosis of

gadflies of the autumn generation a delay in the

development of larvae of the 1st stage, which
reached 6.5-7 months.
According to P.V. Semenov (1985), A.S. Pushkarev

(1986), larvae of the 2nd and 3rd stages produce
metabolites that have an ¬inhibitory effect on

larvae of the 1st stage. Thanks to this evolutionarily
developed technique, the number of O. ovis larvae

is preserved in the parasite carrier's div ¬, while
minimizing harm to the host div. It is possible

that the delay in the development of stage 1 larvae

is due to the immune reactions of the host div to
the increasing intensity of the botfly invasion.
The development of two generations of the banded

gadfly in the spring-summer period in Uzbekistan
is reported by E. I. Gan (1942), in Ukraine - Yu. S.

Kolomiets (1956), in Kyrgyzstan - A. Tuganbaev
(1968), in the steppe zone North Caucasus - N.F.

Shcherban, V.I. Ternovoy (1971).
A. S. Smychkov, N. A. Kodenatsii (1975) report that

climatic conditions in the steppe zone of the Omsk
region create the prerequisites for the

development of one generation of the sheep gadfly.
According to V.S. Akchurin, Kh.F. Ayupov (1957),

P.V. Semenov (1980), I.M. Migunov (1972), ¬only

one generation is developing in the Altai Territory,

Bashkiria, Buryatia, and Chita Region sheep gadfly.
The sheep gadfly is widespread. This species has

been recorded in Bashkiria, Buryatia, Azerbaijan,

Ukraine , Kazakhstan, Kyrgyzstan, Uzbekistan,
certain regions of Siberia, Altai Territory, the Far

East, Orenburg Region, in the south of the
European part of the Russian Federation

(Baskakov V.P., 1936, 1946; Klenin I. I., 1958;
Kolomiets Yu. S., Alfimova A. V., 1956; Dukalov I. A.,

1957; Nosik A. F., Goncharov O. P., 1956; ; Makevnin

S. G., 1956; Spiryukhov S. N., 1962; Dzhamuratov U.,
1965;
A., 1966; Tuganbaev A. T., 1968; Bukshtynov V.I.,

Sultanov F.R., 1970; Alekhine ¬R. M., 1971;
Ponomarev I. A., 1971; Karpenko I. G., 1971;

Migunov I. M., 1971; Ishmuradov A., 1971; Ternova
V.I., 1971; Pokidov I.I., 1974;. Azimov Sh. A, 1978;

Kamarli A.P., Tuganbaev A.T., 1980; Sivkov G.S.
Yamov V. 3, 1981; Marchenko V. A., 1985;

Mozulyaka N. S., Zolotukhina L. 3., 1994; Sivkov

G.S., 1995; Tolokonnikov V.P., 1995; Zharov V. G.,
Remez V. I., 1997; Migunov I.V., 1998; Marchenko

V. A., 1998; Moiseev O.N., 1999; Abramov V. E.,
1999; Lysenko I. O., 2001; Okrut S.V., 2003;

Stepanenko E. E., 2004; Bulkhukova U.P., 2005;
Atayeva U. B., 2006).

Distribution of oestrosis in sheep

Estrosis is an invasive disease of sheep caused by

the larvae of the cavitated gadfly that parasitize the

nasal and frontal sinuses.This description likely
refers to a parasitic infection caused by larvae of

certain parasites, such as nasal bots or nasal
maggots.These larvae can infest the nasal passages

and sinuses of animals, causing irritation,
inflammation, and various symptoms in the

affected host.The larvae may also migrate to other
parts of the div, leading to additional


background image

THE USA JOURNALS

THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY
(ISSN

2689-0968)

VOLUME 06 ISSUE03

27

https://www.theamericanjournals.com/index.php/tajvswd

complications and symptoms.
Treatment for such infections typically involves

removing the larvae from the affected areas, often
through manual extraction or medication. It is

important to consult a veterinarian for proper
diagnosis and treatment of parasitic infections in

animals
The sheep botfly is an obligate parasite of sheep.

There is information that the larvae ¬of the banded
gadfly parasitize goats, argali, aurochs, agali, dogs,

and humans (Grunin K.N., 1957; Abul - Hab , 1970;
Misra et al . , 1976, Grebenyuk P. V., 1955; Grunin

K.N., 1953, Oldroyd , 1964, Pavlovsky E.N., 1929;
Grunin K.N., 1957; Schmial , 1944; Oldroyd 1961;

Shcherban N.F. 1971, etc.).
The wide distribution of the sheep gadfly indicates

the pronounced ecological plasticity of this species,

capable of adapting to ¬changing environmental

conditions in different regions of the planet.
Data on the spread of estrosis in sheep indirectly

indicate the relevance of this problem for modern

sheep farming, the need to develop effective
measures to combat it, and reduce the economic

damage caused.
N.F. Shcherban (1971) notes that in the Rostov

region the extent of estrous infestation (E.I.) is
96.4-98.2% with an average annual intensity of

infestation of 34.1-35.6 larvae per head.
In Kalmykia, 85.7% of sheep are infested. The

intensity of invasion (I.I.) reaches 11.1 specimens

per animal (Ponomarev I.A., 1971).
According to N.S. Mozulyaki (1994), in the steppe

zone of the Stavropol Territory, young sheep (up to
one year) are affected more often than adult

animals. The intensity of infestation in lambs is
20.5-87, in adult sheep - 13.12 larvae per animal.

The extent of invasion in lambs ¬reaches 98%, in
adult animals - 85.2%.
L. 3. Zolotukhina (1995) found that ¬sheep in the

arid zone suffer from estrosis to a lesser extent,

where E.I. in adult livestock it is 46.4%, in young
livestock - 51.2%, and I.I. 9.3-10.0 larvae per head.

In the moderately humid zone, E.I. in adult animals
it reaches 75%, in young animals - 77.5%, I.I. 14.2-

14.3 larvae. In the unstable wet zone E.I. is 53.2%,
and 55.2%, I.I. - 16.0-16.9 larvae.
V.P. Tolokonnikov (1995) reports that the extent of

gadfly invasion ¬in the Stavropol Territory is 71

100%; I.I. varies between 12.1-27.1 larval
specimens per animal.
In the Stavropol Territory, estrose is widespread.

Animals of all sex and age groups are affected

(rams and rams are infected more often than ewes
and lambs). The extent of estrous invasion ¬is 78%,

the intensity is 41 larvae (Stepanenko E. E., 2004).
In Siberia, the maximum I.I. reaches 100 copies per

animal in sheep ¬. E.I. - 71.1-93.6% (Marchenko

V.A., 1998).
The incidence of estrosis in adult sheep in the Chita

region reaches 60.1%, in young sheep - 74.9%. The
intensity of invasion is 28.5 and 21.3 -larvae per

animal (Migunov I.V., 1971).
In May 1986, the number of sheep with estrosis in

the Volga region reached ¬100% with an

infestation intensity of 1-20 larvae per animal
(Bukshtynov V.I., 1987).
V.L. Shamin (1996) reports that in the Orenburg

region in two ¬natural climatic zones (forest-

steppe and steppe), the extent of gadfly infestation
was 81.8%, with an intensity of 24.6 larvae.
According to S. Sagasarra (2000) in Sicily E.I.

reaches its maximum in August and is 83.3%. The

average number of parasites per affected ¬sheep
was 9 larvae, of which 3.9 were in the first stage,

2.7 in the second stage, and 2.8 in the third stage.
A. Scala (2001) provides data on the prevalence of

oestrosis in sheep on the ¬island of Sardinia. Notes

that in sheep aged 2 or more years, the incidence of
estrosis in animals varied from 87 to 100%.
The widespread prevalence of oestrosis indicates

that this disease ¬is a significant obstacle to

increasing the productivity of sheep breeding as an
industry and causes significant economic damage.
The above argues for the need to study the

pathogenetic ¬basis of the functioning of the

“parasite

-

host” system in estr

osis, and to develop

effective control measures that make it possible to


background image

THE USA JOURNALS

THE AMERICAN JOURNAL OF VETERINARY SCIENCES AND WILDLIFE DISCOVERY
(ISSN

2689-0968)

VOLUME 06 ISSUE03

28

https://www.theamericanjournals.com/index.php/tajvswd

reduce the economic damage caused by this
disease to an economically imperceptible level.

CONCLUSION

Overall, the improved drug application device

simplifies the process of treating infested animals,

particularly sheep with oestosis. It not only
increases treatment efficiency but also promotes

cost-effective drug usage and environmental

protection from pesticide pollution. Understanding
the effects of O. ovis larval phases on host

organisms can help determine treatment timing
and preventive measures for estrosis in sheep, as

well as expand the range of safe drugs for use and
ensure high-quality livestock products.

REFERENCES
1.

Arkhipov, I. A. Prevention and treatment of

parasitosis of large and small cattle / I. A.

Arkhipov, A. V. Sorokina // Veterinary
Medicine.

2001. -

№2.

-S. 8-12.

2.

Ataeva, U. B. Distribution, biology, ecology of

Oestrus ovis line , 1758 and Wohlfahrtia
magnifica Schiner , 1861 lowland Dagestan and

¬improvement of control measures: author's

abstract. dis. ...cand. biol. Sciences / U. B.
Ataeva. - Makhachkala, 2006. - 18 p.

3.

Bulkhukova U.P. Epizootology of oestrosis of

sheep in the arid zone of southern Russia / U.P.
Bulkhukova // Tr. / All-Russian Institute of

Helminthology. - M., 2005. - T.41.-S. 107-112.

4.

Moiseev, O. N. Non-contact technologies for

combating estrosis in sheep / O. N. Moiseev, V.
I. Baranov, N. F. Firsov // Vesti, veterinary

medicine. - 1999. - No. 1.-S. 82-87.

5.

Moiseev, O. N. Robots for non-contact

treatment of sheep with aerosols ¬during

estrosis and biological prerequisites for their
use / O. N. Moiseev // Vesti, veterinary

medicine. - 2000. - No. 16(2). - P. 36-44.

6.

Moiseev, O. N. Estrosis of sheep, the fight

against it in the southern regions of Russia

¬Current problems of scientific support for
sustainable development of livestock farming

in the Southern Federal District / O. N. Moiseev

// North Caucasus. zones scientific research
veterinarian, int. - 2006. - P. 67-70.

7.

Tolokonnikov, V.P. Morphofunctional aspects

of the function of onion of the parasite-host
system in oestrosis of sheep / V.P.

Tolokonnikov, I.O. Lysenko // Current
problems of invasion, infection, and non-

infection. animal pathology ¬. - Stavropol,
2003. - P. 132-138.

8.

Biu, AA Nwosu CO Incidence of Oestrus ovis

infestation in Borno-White sahel goats in the

semi-arid zone of Nigeria / AA Biu // Veter.
Res.

1999. -Vol. 30, no. 1.

P. 109-112.

9.

Frugere, S. Immunization of lambs with

excretory secretory products of Oestrus ovis

third

instar

larvae

and

subsequent

experimental challenge / S. Frugere, A. Cota

Leon, F. Prevot Cepeda // Veter, ites. - 2000. -
Vol.31, No. 5. - P. 527-535.

10.

Nishanov, D. Kh., Zhabborov, G. G., &

Raimkulov, I. Kh. (2023). DEMODECOSING
ITLAR

ORASIDA

TARKALISHI

VA

DIAGNOSTIKASI. EDUCATION, SCIENCE AND
INNOVATION IDEAS IN THE WORLD , 14 (5),

133-134.

11.

Rustamov, B. S., & Davlatov, R. B. (2021).

KURKALAR HISTOMONOSINI DAVOLASH VA
OLDINI OLISHDA VITAMINL COMPLEKSLARNI

SINOVDAN OTKAZISH. Bulletin of Veterinary
and Animal Husbandry , 1 (2).

12.

Rustamov, BS, & Davlatov, RB Prevalence and

Treatment

of

Turkeys

Histomonosissamarkand

Institute

of

Veterinary Medicine. International Journal of

Innovations in Engineering Research and
Technology , 1 , 1-5.

13.

Rustamov, B. S. (2021). An effective means of

preventing and treating turkey histomoniasis.


References

Arkhipov, I. A. Prevention and treatment of parasitosis of large and small cattle / I. A. Arkhipov, A. V. Sorokina // Veterinary Medicine. — 2001. -№2.-S. 8-12.

Ataeva, U. B. Distribution, biology, ecology of Oestrus ovis line , 1758 and Wohlfahrtia magnifica Schiner , 1861 lowland Dagestan and ¬improvement of control measures: author's abstract. dis. ...cand. biol. Sciences / U. B. Ataeva. - Makhachkala, 2006. - 18 p.

Bulkhukova U.P. Epizootology of oestrosis of sheep in the arid zone of southern Russia / U.P. Bulkhukova // Tr. / All-Russian Institute of Helminthology. - M., 2005. - T.41.-S. 107-112.

Moiseev, O. N. Non-contact technologies for combating estrosis in sheep / O. N. Moiseev, V. I. Baranov, N. F. Firsov // Vesti, veterinary medicine. - 1999. - No. 1.-S. 82-87.

Moiseev, O. N. Robots for non-contact treatment of sheep with aerosols ¬during estrosis and biological prerequisites for their use / O. N. Moiseev // Vesti, veterinary medicine. - 2000. - No. 16(2). - P. 36-44.

Moiseev, O. N. Estrosis of sheep, the fight against it in the southern regions of Russia ¬Current problems of scientific support for sustainable development of livestock farming in the Southern Federal District / O. N. Moiseev // North Caucasus. zones scientific research veterinarian, int. - 2006. - P. 67-70.

Tolokonnikov, V.P. Morphofunctional aspects of the function of onion of the parasite-host system in oestrosis of sheep / V.P. Tolokonnikov, I.O. Lysenko // Current problems of invasion, infection, and non-infection. animal pathology ¬. - Stavropol, 2003. - P. 132-138.

Biu, AA Nwosu CO Incidence of Oestrus ovis infestation in Borno-White sahel goats in the semi-arid zone of Nigeria / AA Biu // Veter. Res. — 1999. -Vol. 30, no. 1. — P. 109-112.

Frugere, S. Immunization of lambs with excretory secretory products of Oestrus ovis third instar larvae and subsequent experimental challenge / S. Frugere, A. Cota Leon, F. Prevot Cepeda // Veter, ites. - 2000. - Vol.31, No. 5. - P. 527-535.

Nishanov, D. Kh., Zhabborov, G. G., & Raimkulov, I. Kh. (2023). DEMODECOSING ITLAR ORASIDA TARKALISHI VA DIAGNOSTIKASI. EDUCATION, SCIENCE AND INNOVATION IDEAS IN THE WORLD , 14 (5), 133-134.

Rustamov, B. S., & Davlatov, R. B. (2021). KURKALAR HISTOMONOSINI DAVOLASH VA OLDINI OLISHDA VITAMINL COMPLEKSLARNI SINOVDAN OTKAZISH. Bulletin of Veterinary and Animal Husbandry , 1 (2).

Rustamov, BS, & Davlatov, RB Prevalence and Treatment of Turkeys Histomonosissamarkand Institute of Veterinary Medicine. International Journal of Innovations in Engineering Research and Technology , 1 , 1-5.

Rustamov, B. S. (2021). An effective means of preventing and treating turkey histomoniasis.