149
Under our supervision were women: 132 (I trimester); 110 (II trimester)
and 95 (III trimester) of pregnancy. 50 women of comparable age made up the
control group.
The state of periodontal tissues was assessed using the community periodontal
index (CPITN), developed by experts from the WHO/FDI working group for
epidemiological dental surveys of the population. This index allows you to determine
the prevalence and intensity of signs of periodontal tissue damage (gingival bleeding
during probing, the presence of sub- and supragingival tartar, periodontal pockets of
various depths) based on a sextant examination of the oral cavity.
As can be seen from the presented data in pregnant women, there is a sharp
increase in the number of sextants, reflecting a severe inflammatory-destructive
lesion of the periodontium. Thus, the number of sextants with bleeding (code 1)
increased by 5.38% (
Р>0.05); with tartar (code2)
– already by 38.17% (P<0.01); and
with a pocket >6 mm
– by 1600.0% (P<0.01); at the same time, unaccounted for
sextants appear in pregnant women (code X), which is absent in the control group.
Thus, in pregnant women, a sharp increase in the extreme degree of
periodontal damage is recorded, corresponding to high codes of the CPITN index.
References:
1.
Юлдашева
Н.А. «Состояние системы перекисного окисления липидов
ротовой жидкости у женщин с воспалительными заболеваниями пародонта в
разные периоды беременности»
.
Стоматология 95.5 (2016): 19 23.
2.
Юлдашева, Насиба, and Шоира Усманова. «Оценка состояния
пародонта по cpitn индексу в период беременности»
. Inter Conf (2020).
3. Shukurova, U. A., et al. “Local phytotherapy of chronic generalized periodontitis”.
ACADEMICIA: An International Multidisciplinary Research Journal 11A (2021)
INFLUENCE OF PERIODONTITIS ON DEGREE OF GRAVITY OF
CURRENT COVID
-
19
Yusupova N.A., Akramova R.S.
Tashkent state dental Institute, Uzbekistan
Relevance.
A strain of coronavirus SARS-CoV-2 associated with severe acute
respiratory syndrome belonging to the subgenus Sarbecovirus of the genus
Betacoronavirus is a causative agent of coronavirus infection COVID-2019.
According to Johns Hopkins University, which maintains statistics on the incidence
of coronavirus, as of February 21, 2022, more than 424 million infections with the
virus were detected in the world, about 5.9 million people died.
The severity of COVID-19 infection has been associated with patients’
comorbidities (Wu et al., 2020), old age, and obesity (Zhou et al., 2020). However,
to date, specific risk factors leading to worsening clinical outcomes have not been
fully elucidated. Periodontitis is one of the most common chronic inflammatory
150
diseases (Eke et al., 2015). According to a study of epidemiological studies, 50%
of adults suffer from mild to moderate periodontitis, severe form – 10%, which
makes it the sixth most common disease of all mankind (Kassebaum et al., 2014;
Petersen PE & H, 2012).
The purpose of the study.
The aim of this study was to assess the extent of
the effect of periodontitis on the occurrence of COVID-19 complications.
Research materials and methods.
Clinical, hygienic, microbiological,
radiological and biochemical research methods will be used to solve the tasks.
Results of the study.
The results of the study showed that periodontitis was
associated with an increased risk of developing general complications of COVID-
19, hospitalization in the intensive care unit, and the need for mechanical
ventilation in non-smoking patients, diabetic patients, and patients aged 18 to 40
years.After adjustment, periodontitis still had a significant impact on the course
of COVID-19 infection, with significant associations COVID 19 complications (OR
= 3.67, 95% CI 1.46-9.27), death (OR =8.81, 95% CI 1.00-77.7), ICU admission (OR
= 3.54, 95% CI 1.39-9.05) and need for assisted ventilation (OR = 4.57, 95% CI
1.19-17.4) (Nadya Marouf,Wenji Cai,Khalid N. Said.,Journal of Clinical
Periodontology, 2021)
Conclusions.Periodontitis significantly increased the risk of developing
COVID-19 complications, including hospitalization in the intensive care unit, the
need for mechanical ventilation, fatality, and was also associated with increased
levels of blood markers such as D-dimer, white blood cells, and C-reactive protein
adversely affecting outcome in COVID-19
References:
1.
Усманова, Шоира Равшанбековна, and Днлрабо Давлатназаровна
Давлатова. «Дисфункция эндотелиоцитов у больных хроническим
генерализованным пародонтитом»
.
Интернаука 44 (2020): 62
–64.
2.
Камилов, Хайдар, et al. «Вкусовая чувствительность языка у пациентов
с глоссалгией, перенесших covid
-
19 на этапе реабилитации»
.
Журнал
стоматологии и краниофациальных исследований 2.3 (2021): 11
-15.
3.
Алимова, Доно Миржамоловна, and Латофат Гайратжоновна
Фазылова. «Повышение эффективности лечения больных с хроническим
генерализованным пародонтитом после перенесенного коронавирусной
инфекцией covid
-19
»
.
Высшая школа: научные исследования. 2021.
