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EFFECTIVENESS OF ANTIHELMINTIC MEDICINES IN THE TREATMENT OF
FASCIOLYSIS IN GOATS IN THE CONDITIONS OF SURKHANDARYO REGION
Togaymuradov Mansur Salomatovich
Independent researcher. (Department of Zooengineering,
Veterinary Medicine and Sericulture,
Termez State University of Engineering and Agrotechnology)
E-mail: togaymurodov69@inbox.ru
https://doi.org/10.5281/zenodo.15471733
Key words:
Fasciola hepatica, Fasciola gigantica bioekologiya, trematod, gelmint,
geksaxloretan, geksaxlorparaksilol, geksixol, bitionol, sulfen, diamfenetid, zanil, fazineks,
doveniks, rafoksanid, dertil, albendazol, alben, rolenol.
Currently, in the fight against and prevention of fascioliasis in goats, it is necessary to
pay attention to its regional epizootological characteristics, bioecology, and the intensity of
invasion of pathogens. It is also advisable to improve the methods of prevention and
treatment of the disease based on the mechanism of action of the tested drugs, their
application processes, and cost.
The majority of livestock, especially goats, currently kept in the Republic of Uzbekistan
is kept in the care of the population, therefore, all personal assistants, farmers and farms
require timely, high-quality and planned implementation of treatment and preventive
measures against helminthiasis and other dangerous parasitic diseases. Today, the territory of
the Republic of Uzbekistan has created a large number of private veterinary pharmacies, and
wide opportunities have been created for the import of many new anthelmintic and other
medicinal products from abroad. Currently, these pharmacies have anthelmintic drugs of
various forms and compositions used against helminthiasis, in particular, helminths of small
horned animals. Among them, albendazole, which is inexpensive and its various
pharmaceutical forms, is currently one of the most widely used medicinal anthelmintic agents
in veterinary practice for the treatment of fascioliasis in goats. Also, in current production
practice, veterinary specialists or animal owners are using these drugs unplanned, in excess of
the norm, many times, and in some cases, the same anthelmintic is repeatedly used on
animals every month. Such unplanned deworming activities cause a number of unpleasant
situations, such as increased costs, poisoning of the animal div, as well as harm to the
quality of products obtained from animals and their health due to their consumption by
humans. When treating fascioliasis in goats, it is advisable, first of all, to take into account the
season and type of trematode that causes it, the intensity of the invasion, and the course of the
disease, based on the regional epizootological characteristics of this disease, and to select
anthelmintic drugs and determine the duration of their use.
For many years, preparations such as carbon tetrachloride, hexachloroethane,
hexachloroparaxylene, hexychol, bithionol, sulfen, diamphenetide, zanil, fazinex, dovenix,
rafoxanide, dertil have been used to treat fascioliasis in goats. However, in recent years, the
influx of new medicinal substances from foreign countries has increased, and the
improvement in the quality of private veterinary pharmacies has created the opportunity to
recommend several types of drugs for a particular disease. As a result, the type of drugs used
against fascioliasis has changed, and the old anthelmintics have been replaced by combined
ones with new properties. Examples of such new chemical preparations include all
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albendazole preparations (alben, albasafe, albendazole, albenol, helmintol, albazen, albendex,
bendaz, etc.), rolenol, brontel-10, closan-50, closantel, faskotsid, helmicid, and many other
chemical preparations.
Conclusions:
1. For many years, preparations such as carbon tetrachloride, hexachloroethane,
hexachloroparaxylene, hexychol, bithionol, sulfen, diamphenetide, zanil, fazinex, dovenix,
rafoxanide, dertil have been used to treat fascioliasis in goats. However, in recent years, the
influx of new medicinal substances from foreign countries has increased, and the quality of
private veterinary pharmacies has improved, which has made it possible to recommend
several types of drugs for a particular disease. As a result, the type of drugs used against
fascioliasis has changed, and the old anthelmintics have been replaced by combined ones with
new properties. Examples of such new chemical preparations include all albendazole
preparations (alben, albasafe, albendazole, albenol, helmintol, albazen, albendex, bendaz, etc.),
rolenol, brontel-10, closan-50, closantel, faskotsid, helmicid, and many other chemical
preparations.
2. Taking into account the extensive and intensive effectiveness of all the used
anthelmintic drugs against fascioliasis in goats, when conditionally evaluating their
effectiveness, we note Rolenol injection solution in the first place, Albendazole 10%
suspension in the second place, and Alben tablets in the third place. However, when analyzed
in terms of economic cost and average cost, Metsalben suspension is a relatively cheap and
convenient drug to use. Closantel-50 solution is also a relatively cheap and convenient
anthelmintic.
References:
Используемая литература:
Foydalanilgan adabiyotlar:
1.
Ergashev E.Kh., Abdurakhmanov T.A. Helminthic diseases of livestock. // Textbook.
Tashkent Publishing House "Mehnat", 1992. 208 p.
2.
Salimov B.S., Otaboev Kh., Taylokov T.I. Exacerbation of the epizootological situation of
fascioliasis, dicroceliosis and gastrotyliacosis of sheep in the conditions of the Samarkand
region. Journal of Zooveterinary Sciences. Tashkent 2012. №7-8. P.17
3.
Salimov B.S, Daminov A.S, Urokov K.Kh. Trematodoses of farm animals and poultry.//
Monograph. Samarkand-2016.219 pp.
4.
Salimov B.S, Taylokov T.I, Kurbonov Sh, Otaboev Kh. New data on the important
biological, ecological, pathogenetic properties of liver flukes in Uzbekistan. // Prospects for
the development of veterinary medicine and animal husbandry: modern practice and
innovative technologies. Collection of materials of the Republican scientific and practical
conference. Samarkand-2020
5.
Daminov A.S. Taylokov T.I. The spread of fascioliasis of goats in the foothill and
mountain zones of the Samarkand region.// Journal of Livestock and Breeding. Tashkent,
2022. No. 6.-P.40-41.
