Diabetes mellitus is a chronic metabolic disorder characterized by impaired insulin production or insulin resistance, affecting millions of individuals worldwide. Peri-operative management of diabetes in surgical patients poses unique challenges due to the potential impact on glycemic control, wound healing, and post-operative complications. This review aims to explore the strategies and considerations for peri-operative management of diabetes mellitus. Key aspects include pre-operative assessment and optimization of glycemic control, individualized insulin regimens, management of peri-operative hyperglycemia, and post-operative monitoring and care. Additionally, the role of multidisciplinary collaboration, patient education, and risk stratification for surgical procedures is discussed. Adherence to evidence-based guidelines, close monitoring, and tailored interventions can contribute to improved outcomes and reduced complications in surgical patients with diabetes. Healthcare providers involved in peri-operative care should be knowledgeable about the unique considerations and best practices in managing diabetes during the peri-operative period.