Authors

  • Khidoyatova Zulfiya Sharifovna
    Associate Professor Candidate of Biological Sciences Tashkent Pharmaceutical Institute, Department of Organization of Pharmaceutical Work, Uzbekistan
  • Azimova Munira Takhirovna
    Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, Senior Lecturer, Uzbekistan
  • Urazbayeva Shakhrizoda Oybek kizi
    Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, assistant, Uzbekistan
  • Zhuraeva Sitora Lutfullaevna
    Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, assistant, Uzbekistan

DOI:

https://doi.org/10.37547/ajbspi/Volume05Issue05-02

Keywords:

Diabetes glucose insulin metabolism

Abstract

This article discusses the importance of phytotherapy in diabetes mellitus, medicinal plants used in medicine to lower blood sugar levels, and biologically active additives derived from them and various remedies based on them used in diabetes prevention. During the research, the results of studying several representatives of medicinal plants and their properties, instructions for use, and their technological properties are presented.


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American Journal Of Biomedical Science & Pharmaceutical Innovation

5

https://theusajournals.com/index.php/ajbspi

VOLUME

Vol.05 Issue05 2025

PAGE NO.

5-7

DOI

10.37547/ajbspi/Volume05Issue05-02



The Importance of Phytotherapy In Diabetesia, Analysis
of Medicinal Plants and Methods of Their Application

Khidoyatova Zulfiya Sharifovna

Associate Professor Candidate of Biological Sciences Tashkent Pharmaceutical Institute, Department of Organization of Pharmaceutical
Work, Uzbekistan

Azimova Munira Takhirovna

Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, Senior Lecturer, Uzbekistan

Urazbayeva Shakhrizoda Oybek kizi

Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, assistant, Uzbekistan

Zhuraeva Sitora Lutfullaevna

Tashkent Pharmaceutical Institute, Department of Pharmaceutical Work Organization, assistant, Uzbekistan

Received:

23 March 2025;

Accepted:

19 April 2025;

Published:

21 May 2025

Abstract:

This article discusses the importance of phytotherapy in diabetes mellitus, medicinal plants used in

medicine to lower blood sugar levels, and biologically active additives derived from them and various remedies
based on them used in diabetes prevention. During the research, the results of studying several representatives
of medicinal plants and their properties, instructions for use, and their technological properties are presented.

Keywords:

Diabetes, glucose, insulin, metabolism, phytotea, bioactive additive, infusion, decoction.

Introduction:

Currently, there is a growing demand and

interest in medicines of natural origin in our country
and abroad, especially medicines obtained on the basis
of medicinal plants. The terms phytopreparation,
phytobar, or phytotherapy are accepted by the general
public. The variety of phytopreparations and various
teas sold in pharmacies is also increasing. Along with
the development of the phytocosm, the requirements
for it are also increasing, increasing the quality and
competitiveness of products. Effective clinical trials of
new plant-based molecules and a reduction in the
proportion of chemotherapeutic agents are becoming
a requirement of the times. It should be noted that
phytopreparations cannot replace treatment with full-
fledged medications, but with their help, it is possible
to strengthen health and normalize the patient's
general condition.

Type 2 diabetes mellitus is an endocrine disease
characterized by impaired glucose tolerance. It is

among the top ten fatal diseases [1]. The pancreas
produces a sufficient amount of the hormone insulin,
but the impaired sensitivity of tissues to glucose leads
to the inability to break down sugar. To achieve normal
glucose levels, sugar-lowering medications, special
diets, and physical exercises are used. Medicinal plants
also participate in reducing blood glucose levels in type
2 diabetes mellitus, and additionally introduce vitamins
into the div and strengthen the immune system [2].

Purpose of the work

. Study of the importance of

medicinal plants in the treatment of diabetes mellitus
and the properties of some medicinal plants
recommended for use.

METHODS

Raw materials used to normalize blood and urine sugar
levels, i.e., plants that exhibit medicinal properties due
to natural compounds similar to insulin in their
composition, such as blue cornflower, clover,


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American Journal of Applied Science and Technology

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American Journal of Applied Science and Technology (ISSN: 2771-2745)

blueberry, and andiz, were analytically studied. By
regularly using the above-mentioned medicinal plants,
it is possible to reduce the dose of sugar-lowering drugs
and even replace them. It has properties of natural
removal of excess glucose from the div, prevention of
diabetic complications such as damage to eyes, liver,
kidneys, blood vessels, skin, restoration of pancreatic
function, strengthening general health, increasing
immunity, improving psychological state, normalizing
sleep [3].

RESULTS

When collecting medicinal plants from natural areas, it
is preferable to collect them from representatives
growing in ecologically clean areas, such as mountains,
forests, riverbanks, plains, and similar areas where
human intervention is minimal. The use of roadsides,
industrial zones, animal pastures, and raw materials of
unguaranteed quality is not recommended.

Plants used in type 2 diabetes. When treating diabetes,
the type of plant is selected according to the set
therapeutic objectives. Since plants that restore
metabolism are directly related to the disruption of
metabolic processes in tissues in type 2 diabetes
mellitus, it is necessary to use plants that enhance
metabolic processes during the disease. In this case,
plants such as plantain, lemon grass, dandelion, black
tea, and mingbarg are used. For general strengthening
of the organism, wormwood, chicory, ginseng, hibiscus,
fragrant ruta and others are used, while sugar-lowering
agents include nettle root, meadow clover, andiz
leaves, blueberry leaves, cufflinks, licorice root and
others. Medicinal plants are used separately, as well as
in combinations of several plants. In addition, a
separate plant extract or a mixture of several plant
extracts in certain proportions is used. In addition, a
separate plant extract or a mixture of several plant
extracts in certain proportions is used. Despite the
seemingly safe nature of phytotherapy, in some cases,
treatment with plants is strictly prohibited, and these
include: a predisposition to allergies, severe diabetes,
and its life-threatening complications - hypoglycemic,
hyperglycemic coma, and other conditions.

Medicinal plants that lower sugar levels. Sugar-
lowering plants are part of many preparations used for
type 2 diabetes mellitus. These plants are rich in insulin-
like substances that regulate blood glucose
concentration [4].

Centaurea

(Centaurea cyanus L.) is an annual

herbaceous plant of the Asteraceae family, reaching up
to 1 m in height. Its product contains essential oils,
vitamins and minerals, anthocyanins, coumarins -
cycornine, as well as glycoside-centaurin and other
substances [5]. It is recommended to drink a decoction

made from the plant's root.

Preparation method: crush the dried leaves and roots
of the plant, place one tablespoon of raw material in an
enameled dish, pour a glass of boiling water over the
product, let it steep in a water bath for about 25
minutes, cool the prepared decoction, strain through a
cloth or fine sieve. The drink should be taken one
tablespoon three times a day before meals. The course
of treatment is 30 days.

Clover

(Trifolium) is an annual, biennial, and perennial

herbaceous plant belonging to the legume family; its
leaves contain carotene, phytoestrogens, flavonoids,
tannins, proteins, fats, organic acids, numerous
vitamins, and minerals. It has been scientifically proven
that celery helps normalize glucose concentration in
the div [6].

Preparation method: add one teaspoon of chopped
clover leaves to one cup of cooled water, mix well, let
steep for half an hour, then strain the drink and drink 2
tablespoons each time before meals. The drinking
period should last at least one month.

Blueberry leaves

. The fruits and leaves of common

blueberry (Vaccinium myrtillus L.) contain a large
number of components that can have a positive effect
on the whole organism. These include amber, apple,
acetic acid, beta-carotene, vitamins, and essential oils.
In diabetes mellitus, the plant helps improve pancreatic
function, saturate the div with vitamins, and restore
normal glucose levels [7].

Preparation method: Add one tablespoon of crushed
dried plant leaves to 500 ml of boiling water, let it steep
in steam or water bath for at least half an hour, then
remove the decoction from heat and let it steep well.
Drink 50 ml 4-5 times a day for 30 days, regardless of
meals.

Anise

(Jnula helenium L.) is a perennial herbaceous

plant belonging to the Asteraceae family. The product
consists of thick roots and rhizomes. To stimulate
pancreatic function and reduce blood sugar levels in
the div, patients with type 2 diabetes are prescribed
decoctions made from andiz root [8].

Method of preparing the decoction: pour half a liter of
boiling water over one tablespoon of peeled and
chopped root vegetables, let it steam in a steam bath
for about an hour, cool the prepared decoction, and
strain through a fine sieve or cloth. The drink should be
taken half a glass twice a day before meals.

Method of preparing the tincture: 500 ml of alcohol or
plain vodka should be mixed with 50 g of dry andiz root,
the tincture is kept in a dark room at a cool
temperature for at least 8-10 days. After preparation, it
is filtered and stored in the refrigerator. The obtained


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American Journal of Applied Science and Technology (ISSN: 2771-2745)

medication is taken 20 drops three times a day.

To restore metabolic processes, people with diabetes
are recommended to use medicinal plants that improve
metabolism in the div. Such plants include plantain,
lemon grass, and dandelion.

Plants with general strengthening and vitamin content.
Herbs containing vitamins help saturate the div with
necessary vitamins and minerals, strengthen immunity,
improve emotional state, and normalize the function of
all internal organs and systems. These include dodder,
brusnika, ginseng, eleutherococcus [9].

CONCLUSION

Thus, our analytical studies show that medicinal plants
used in the treatment and prevention of diabetes
mellitus can be used in combination with full-blooded
drugs, even as a substitute for them. Based on the
above information, it can be concluded that plant
materials, infusions, decoctions, and other forms of
anti-diabetic agents are currently widely used in
practice. In experiments, it has been proven that the
therapeutic effectiveness of biologically active
antidiabetic supplements depends on the base of plant-
based active substances. Therefore, the use of
medicinal plant materials is becoming increasingly
important.

REFERENCES

Boltaeva N.O. Study of the effect of the supramolecular
complex of glycyrrhizic acid and quercetin on the
antioxidant system in the liver cells of diabetic rats
Journal of Pharmacy, Immunity and Vaccines, No4,
2024. P. 103.

B. Shogazatova.

🔹

Diet for Diabetes

🔹

"Sihat-

salomatlik" magazine 29.02.2016 P. 7.

https://xn--80aqooi4b.xn--
p1acf/education/articles/kak-diabet-vliyaet-na-
immunitet

.

Samaneh Fattaheian-Dehkordi, Reza Hojjatifard, Mina
Saeedi, Mahnaz Khanavi. A Review on the Antidiabetic
Activity of Centaurea spp.: A New Approach for
Developing

Herbal

Remedies.

"Evidence-Based

Complementary and Alternative Medicine." Volume
2021, Article ID 5587938, 23 p.

https://aromarin.ru/vasilek-sinii-lepestki-travi-
gornogo-krima

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Longxin Qiu1,2,, Tong Chen1,2,, Fojin Zhong1, Yamin
Hong1, Limei Chen1, Hong Ye1. Anti-diabetic and
hypolipidemic

effects

of

clover

extract

in

mice."Experimental and Therapeutic Medicine" 9.09; 4
(4):699-704 p.

References

Boltaeva N.O. Study of the effect of the supramolecular complex of glycyrrhizic acid and quercetin on the antioxidant system in the liver cells of diabetic rats Journal of Pharmacy, Immunity and Vaccines, No4, 2024. P. 103.

B. Shogazatova. ????Diet for Diabetes ???? "Sihat-salomatlik" magazine 29.02.2016 P. 7.

Samaneh Fattaheian-Dehkordi, Reza Hojjatifard, Mina Saeedi, Mahnaz Khanavi. A Review on the Antidiabetic Activity of Centaurea spp.: A New Approach for Developing Herbal Remedies. "Evidence-Based Complementary and Alternative Medicine." Volume 2021, Article ID 5587938, 23 p.

Longxin Qiu1,2,, Tong Chen1,2,, Fojin Zhong1, Yamin Hong1, Limei Chen1, Hong Ye1. Anti-diabetic and hypolipidemic effects of clover extract in mice."Experimental and Therapeutic Medicine" 9.09; 4 (4):699-704 p.