Volume 04 Issue 01-2024
93
American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN
–
2771-2753)
VOLUME
04
ISSUE
01
P
AGES
:
93-97
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
6.534
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
ABSTRACT
Hypersensitivity of hard dental tissues after whitening is one of the most common pathological conditions that create
discomfort and have a negative impact on the functional state of the oral cavity. For treatment, 66 patients aged 30
–
40 years with at least 20
–
25 natural teeth with a preserved crown and without severe concomitant pathology were
selected, with complaints of hyperesthesia of the teeth after professional whitening. Over the course of 6 months,
using clinical methods and subjective sensations of patients, the severity of hyperesthesia after treatment with various
desensitizers was compared . The high efficiency of Telio CS Desensitizer in the treatment and prevention of
hyperesthesia of hard dental tissues was revealed.
KEYWORDS
Hyperesthesia, teeth whitening, desensitizer.
INTRODUCTION
Purpose of the study: comparative assessment of the
clinical effectiveness of various desensitizers in the
prevention and treatment of dental hyperesthesia
after whitening.
Research Article
COMPARISON OF THE EFFECTIVENESS OF TREATMENT FOR DENTAL
HYPERESTHESIA
Submission Date:
January 21, 2024,
Accepted Date:
January 26, 2024,
Published Date:
January 31, 2024
Crossref doi:
https://doi.org/10.37547/ajbspi/Volume04Issue01-14
Daminova Sh.B.
Tashkent State Dental Institute, Uzbekistan
Khasanov E.T.
Tashkent State Dental Institute, Uzbekistan
Journal
Website:
https://theusajournals.
com/index.php/ajbspi
Copyright:
Original
content from this work
may be used under the
terms of the creative
commons
attributes
4.0 licence.
Volume 04 Issue 01-2024
94
American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN
–
2771-2753)
VOLUME
04
ISSUE
01
P
AGES
:
93-97
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
6.534
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
Beautiful and attractive teeth, as a sign of social well-
being and beauty, are becoming increasingly in
demand for practical dentistry in all social and age
groups of the population. Scientific research
conducted in this area has shown that people with
dental discoloration often experience certain
problems with social adaptation and are often subject
to some kind of discrimination in society. This leads to
the demand for both the whitening procedure itself
and the range of constantly improved whitening
products and techniques offered in dental clinics.
Increased sensitivity of hard dental tissues, often
observed after whitening, is one of the most common
pathological conditions that create discomfort and
have a negative impact on the functional state of the
mouth. According to some data, hyperesthesia affects
from 15 to 68% of the population, and the causes of its
occurrence are quite numerous. Increased sensitivity
also manifests itself in carious and non-carious lesions,
various damage to the enamel, in particular the
presence of cracks, as well as after preparation of hard
dental tissues. As stated earlier, increased sensitivity
also occurs after professional teeth whitening. The
high demand for this type of dental care also requires
a timely increase in the effectiveness of treatment and
prevention of dental hyperesthesia]. Thus, despite the
achievements of dental materials science in the
development of new means for the treatment and
prevention of dental hypersensitivity (based on
important micro- and macroelements, calcium,
fluorides, as well as modern desensitizers) that
improve the quality of life of the population, there is
still a need for further study and comparative
assessment of the clinical effectiveness of modern
drugs, and on this basis - their optimal individual choice
for each clinical situation.
MATERIALS AND METHODS
To determine the causes of discoloration , we
interviewed 66 patients aged 30 to 40 years who
wanted to improve the color aesthetics of their teeth
and change their color using professional chemical
whitening. In 35% of respondents, staining of the
surface of the crowns of vital teeth is caused by
ingestion of foods rich in dyes. Thus, almost 60% of
respondents regularly drink 2-3 cups of coffee a day,
and almost 15% of respondents drink carbonated drinks
with dyes. One of the main exogenous factors
contributing
to
the
development
of dental
discoloration is smoking. A change in the natural
appearance of tooth crowns was most often found in
unsatisfactory hygienic condition of the oral cavity in
combination with abundant deposition of smoker’s
plaque with subsequent pigmentation of the vestibular
and oral surfaces of the hard tissues of the teeth. A
relatively large proportion of respondents indicated a
low level of effectiveness of previously performed
whitening procedures.
Today, there are many desensitizers from various
manufacturers on the domestic market, operating on
the basis of one or a combination of several
Volume 04 Issue 01-2024
95
American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN
–
2771-2753)
VOLUME
04
ISSUE
01
P
AGES
:
93-97
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
6.534
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
mechanisms. Many desensitizers are based on
modified dentine primer hydroxyethyl methacrylate
(HEMA). Additionally, drugs are introduced into it that
cause sealing of the dentinal tubules, fluorides and
antibacterial components in various combinations. To
achieve this goal, the materials of scientific and medical
resources on the subject under consideration were
studied and analyzed due to the wide variety of
combinations of drugs used to reduce the
hypersensitivity of hard dental tissues. And based on
the results obtained, drugs were selected to assess the
clinical effectiveness of their use. This study involved
66 patients aged 30-40 years, with at least 20-25
natural teeth with a preserved crown and without
severe comorbidity, with complaints of hyperesthesia
of the teeth after professional whitening. In the first
group of patients, the drug was GC " Tooth Mousse "
(Japan). The drug is a water-soluble cream containing
the Recaldent complex , consisting of CPP (casein
phosphopeptide ) and ACP (amorphous calcium
phosphate), which has the ability to bind a large
amount of calcium and phosphate ions, keeping them
in an amorphous non - crystalline state and provides
high adhesion of the drug to the hard tissues of the
tooth, pellicle, plaque components and soft tissues of
the oral cavity, thereby providing a prolonged effect of
the drug. Paste applications were carried out in a
clinical setting in accordance with the manufacturer's
instructions for 3 minutes. Patients were advised to
refrain from eating for 30 minutes. Each patient was
instructed on the use of this drug at home . The drug
was applied 2 times a day with a dry finger or applicator
after brushing the teeth for 5 minutes. For better
penetration of the drug into the interdental spaces, it
was recommended to use floss . During the procedure,
it was not recommended to spit and swallow saliva.
Additional rinsing of the oral cavity was not required.
For the next 30 minutes, you should not drink or eat.
Control examinations of patients were carried out at
the beginning of the study (initial examination) and
during the period of application of the remineralizing
drug - after 1 and 2 weeks. The obtained data were
entered into a special survey card. Gluma was chosen
as the basis for the treatment of patients in the second
group. Desensitizer ( Heraues Kulzer , Germany ) .
Gluma Desensitizer is a product containing HEMA (
hydroxyethyl ) methacrylate , glutaraldehyde and
distilled water. The mechanism of action of this drug is
that it coagulates the proteins of the dentinal fluid
inside the dentinal tubules, forming transverse
partitions that block the movement of dentinal fluid,
which reduces the sensitivity of the dentin. Due to the
presence of HEMA in the composition, its penetration
depth increases to 200 microns (0.2 mm). Paste
applications were carried out in a clinical setting in
accordance with the manufacturer's instructions. To
begin, the dentin to be treated was cleaned under local
anesthesia and then rinsed with water. The mucosa
was protected with a rubber dam. Then, a small
amount of GLUMA® Desensitizer needed for
Volume 04 Issue 01-2024
96
American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN
–
2771-2753)
VOLUME
04
ISSUE
01
P
AGES
:
93-97
SJIF
I
MPACT
FACTOR
(2021:
5.
705
)
(2022:
5.
705
)
(2023:
6.534
)
OCLC
–
1121105677
Publisher:
Oscar Publishing Services
Servi
treatment was applied to the treated dentin surface
with a brush and left for 30-60 seconds. During this
time, we carefully monitored that GLUMA®
Desensitizer did not drip from the application area.
After that, the surface was carefully dried with a jet of
air until the liquid film disappeared and the surface
stopped shining, then washed with plenty of water.
Control examinations of patients were carried out at
the beginning of the study (initial examination) and
during the period of application of the remineralizing
drug - after 1 and 2 weeks.
The results of the study showed that patients in the
first group, when treated with water-based
remineralizing paste GC ToothMousse , had comments
about the pleasant taste and smell, as well as the
convenience and comfort of using this paste. After
using it, the feeling of fresh breath remained for a long
time. During the study period, according to control
dental examinations, there were no cases of local
irritating or allergenic effects of the paste on the oral
mucosa. Thus, regular use of a remineralizing drug
contributed to the fact that in 22 patients (88%)
complaints about tooth sensitivity disappeared, and in
3 (12%) the symptoms of this pathology decreased. In
patients of the second group, on whom GLUMA®
Desensitizer was used , before treatment, all patients
were clinically determined to have a noticeable pain
reaction to irritants. After treatment, dental
hypersensitivity disappeared in 20 (80%) patients, and
decreased in only 5 (20%) patients. We also found that
with repeated local application of GLUMA®
Desensitizer , the therapeutic effect is enhanced. The
results of treatment of patients were assessed using
basic (questioning, examination) and additional (
thermal diagnostics ) research methods.
Conclusion
Thus, our research has shown that the most effective
remedy for reducing tooth sensitivity was the water-
based remineralizing paste GC ToothMousse .
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American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN
–
2771-2753)
VOLUME
04
ISSUE
01
P
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93-97
SJIF
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FACTOR
(2021:
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1121105677
Publisher:
Oscar Publishing Services
Servi
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