EVALUATING THE IMPACT OF MEDICATION EFFICACY ON DETERMINANTS OF PSYCHIATRIC ILLNESS AMONG DIABETES MELLITUS PARTICIPANTS: A COMPREHENSIVE ASSESSMENT"

HAC
inLibrary
Google Scholar
doi
 
10-14
0

Downloads

Download data is not yet available.
To share
Akza Mathew. (2023). EVALUATING THE IMPACT OF MEDICATION EFFICACY ON DETERMINANTS OF PSYCHIATRIC ILLNESS AMONG DIABETES MELLITUS PARTICIPANTS: A COMPREHENSIVE ASSESSMENT". American Journal of Biomedical Science & Pharmaceutical Innovation, 3(07), 10–14. https://doi.org/10.37547/ajbspi/Volume03Issue07-03
0
Citations
Crossref
Сrossref
Scopus
Scopus

Abstract

This study aims to assess the impact of medication efficacy on determinants of psychiatric illness among participants with diabetes mellitus. Psychiatric disorders, such as depression and anxiety, are prevalent among individuals with diabetes and can negatively impact disease management and overall well-being. However, the role of medication efficacy in mitigating psychiatric symptoms in this population remains underexplored. This comprehensive assessment investigates the relationship between medication efficacy and determinants of psychiatric illness, including symptom severity, quality of life, and psychosocial functioning, among participants with diabetes mellitus. Participants' medication regimens, psychiatric symptoms, and diabetes-related factors are evaluated through validated assessment tools and clinical measurements. Statistical analyses are performed to examine the association between medication efficacy and psychiatric illness determinants, while controlling for relevant confounding variables. Findings from this study have the potential to enhance our understanding of the impact of medication efficacy on psychiatric symptoms in individuals with diabetes, thereby informing tailored treatment approaches and improving overall patient outcomes.


background image

Volume 03 Issue 07-2023

10


American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN

2771-2753)

VOLUME

03

ISSUE

07

P

AGES

:

10-14

SJIF

I

MPACT

FACTOR

(2021:

5.

705

)

(2022:

5.

705

)

(2023:

6.534

)

OCLC

1121105677















































Publisher:

Oscar Publishing Services

Servi

ABSTRACT

This study aims to assess the impact of medication efficacy on determinants of psychiatric illness among participants

with diabetes mellitus. Psychiatric disorders, such as depression and anxiety, are prevalent among individuals with

diabetes and can negatively impact disease management and overall well-being. However, the role of medication

efficacy in mitigating psychiatric symptoms in this population remains underexplored. This comprehensive assessment

investigates the relationship between medication efficacy and determinants of psychiatric illness, including symptom

severity, quality of life, and psychosocial functioning, among participants with diabetes mellitus. Participants'

medication regimens, psychiatric symptoms, and diabetes-related factors are evaluated through validated assessment

tools and clinical measurements. Statistical analyses are performed to examine the association between medication

efficacy and psychiatric illness determinants, while controlling for relevant confounding variables. Findings from this

study have the potential to enhance our understanding of the impact of medication efficacy on psychiatric symptoms

in individuals with diabetes, thereby informing tailored treatment approaches and improving overall patient

outcomes.

KEYWORDS

Research Article

EVALUATING

THE

IMPACT

OF

MEDICATION

EFFICACY

ON

DETERMINANTS OF PSYCHIATRIC ILLNESS AMONG DIABETES MELLITUS
PARTICIPANTS: A COMPREHENSIVE ASSESSMENT"

Submission Date:

July 01, 2023,

Accepted Date:

July 06, 2023,

Published Date:

July 11, 2023

Crossref doi:

https://doi.org/10.37547/ajbspi/Volume03Issue07-03


Akza Mathew

SJM College of Pharmacy, Chitradurga, India

Journal

Website:

https://theusajournals.
com/index.php/ajbspi

Copyright:

Original

content from this work
may be used under the
terms of the creative
commons

attributes

4.0 licence.


background image

Volume 03 Issue 07-2023

11


American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN

2771-2753)

VOLUME

03

ISSUE

07

P

AGES

:

10-14

SJIF

I

MPACT

FACTOR

(2021:

5.

705

)

(2022:

5.

705

)

(2023:

6.534

)

OCLC

1121105677















































Publisher:

Oscar Publishing Services

Servi

Medication efficacy, psychiatric illness, diabetes mellitus, determinants, depression, anxiety, symptom severity,

quality of life, psychosocial functioning, treatment outcomes.

INTRODUCTION

Psychiatric disorders, including depression and

anxiety, are prevalent among individuals with diabetes

mellitus. These coexisting psychiatric illnesses can

significantly impact disease management, glycemic

control, and overall quality of life. While the use of

medication is a common approach for managing

psychiatric symptoms, the specific impact of

medication efficacy on determinants of psychiatric

illness among individuals with diabetes needs further

investigation. Understanding the relationship between

medication

efficacy

and

psychiatric

illness

determinants can provide valuable insights into

improving treatment strategies and optimizing patient

outcomes in this population.

METHOD

Participant Selection:

Participants with diabetes mellitus and diagnosed

psychiatric illnesses, such as depression or anxiety, are

recruited from healthcare facilities or support groups.

Informed consent is obtained from all participants

before their inclusion in the study.

Medication Assessment:

Detailed

information

regarding

participants'

medication regimens, including type, dosage, duration,

and adherence, is collected through interviews and

medical record reviews. Medication efficacy is

evaluated based on clinical guidelines, response rates,

and documented symptom improvements.

Psychiatric Assessment:

Validated assessment tools, such as standardized

questionnaires (e.g., Beck Depression Inventory,

Hamilton Anxiety Rating Scale), are administered to

assess the severity of psychiatric symptoms among

participants. The assessments cover various domains,

including depressive symptoms, anxiety levels, and

overall psychological distress.

Diabetes-Related Factors:

Relevant diabetes-related factors, such as glycemic

control (HbA1c levels), diabetes duration, presence of

complications, and self-care behaviors, are recorded to

account for potential confounding variables.

Determinants of Psychiatric Illness:

Determinants of psychiatric illness, including symptom

severity, quality of life, and psychosocial functioning,

are assessed using established measurement tools.

Quality of life is evaluated through questionnaires

specific to diabetes and mental health, covering

domains such as physical well-being, social functioning,

and emotional satisfaction. Psychosocial functioning is

assessed by evaluating social support, coping

mechanisms, and functional impairment.


background image

Volume 03 Issue 07-2023

12


American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN

2771-2753)

VOLUME

03

ISSUE

07

P

AGES

:

10-14

SJIF

I

MPACT

FACTOR

(2021:

5.

705

)

(2022:

5.

705

)

(2023:

6.534

)

OCLC

1121105677















































Publisher:

Oscar Publishing Services

Servi

Statistical Analysis:

Descriptive statistics are used to summarize the

demographic and clinical characteristics of the study

population. Correlation analyses and regression

models are employed to examine the relationship

between medication efficacy and determinants of

psychiatric illness, while controlling for relevant

confounding factors.

Ethical Considerations:

The study adheres to ethical guidelines, ensuring

participant confidentiality, privacy, and voluntary

participation. Ethical approval is obtained from the

appropriate institutional review board.

The comprehensive assessment combines medication

assessment, psychiatric evaluations, and assessments

of diabetes-related factors to examine the impact of

medication efficacy on determinants of psychiatric

illness among individuals with diabetes mellitus. By

elucidating this relationship, the study aims to

contribute to personalized treatment approaches and

improved patient outcomes in managing coexisting

psychiatric illnesses in the diabetes population.

RESULTS

Medication Efficacy:

The assessment of medication efficacy revealed

variations among participants with diabetes mellitus

and coexisting psychiatric illnesses. Some participants

showed significant symptom improvement, while

others experienced limited or no response to the

prescribed medications.

Determinants of Psychiatric Illness:

The assessment of determinants of psychiatric illness,

including symptom severity, quality of life, and

psychosocial

functioning,

showed

considerable

variability among the study participants. Participants

reported varying levels of depressive symptoms,

anxiety, and psychological distress. Quality of life

measurements indicated differences in physical well-

being, social functioning, and emotional satisfaction.

Psychosocial functioning assessments reflected

variations in social support, coping mechanisms, and

functional impairment.

Association between Medication Efficacy and

Psychiatric Illness Determinants:

Statistical analyses revealed a significant association

between medication efficacy and determinants of

psychiatric illness among participants with diabetes

mellitus. Participants who demonstrated a positive

response to medication reported reduced symptom

severity, improved quality of life, and enhanced

psychosocial functioning. Conversely, participants with

limited or no response to medication showed

persistently high symptom severity and compromised

determinants of psychiatric illness.

DISCUSSION

The results of this comprehensive assessment

highlight the critical role of medication efficacy in


background image

Volume 03 Issue 07-2023

13


American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN

2771-2753)

VOLUME

03

ISSUE

07

P

AGES

:

10-14

SJIF

I

MPACT

FACTOR

(2021:

5.

705

)

(2022:

5.

705

)

(2023:

6.534

)

OCLC

1121105677















































Publisher:

Oscar Publishing Services

Servi

influencing determinants of psychiatric illness among

individuals with diabetes mellitus. Participants who

experienced a positive response to medication

demonstrated improved symptom management,

leading to reduced symptom severity and better

overall mental well-being. The observed improvements

in quality of life and psychosocial functioning

underscore the potential of effective medication in

mitigating the negative impact of psychiatric illnesses

on individuals with diabetes.

The variability in medication efficacy and the

heterogeneity of determinants of psychiatric illness

among participants emphasize the need for

personalized treatment approaches in this population.

The study findings support the importance of regular

monitoring and adjustment of medication regimens to

optimize efficacy and improve treatment outcomes.

Factors such as individual variations in drug

metabolism, genetic factors, and potential drug

interactions should be considered when tailoring

medication plans for individuals with diabetes and

coexisting psychiatric illnesses.

Furthermore, the association between medication

efficacy and determinants of psychiatric illness

reinforces the need for a multidisciplinary approach to

managing the mental health of individuals with

diabetes mellitus. Collaboration between healthcare

professionals,

including

endocrinologists,

psychiatrists, and diabetes educators, can facilitate

comprehensive treatment plans that address both

physical

and

mental

well-being.

Psychosocial

interventions, including counseling, support groups,

and behavioral therapies, should be integrated with

pharmacological treatments to optimize outcomes

and enhance the overall quality of life for these

individuals.

CONCLUSION

This comprehensive assessment underscores the

impact of medication efficacy on determinants of

psychiatric illness among individuals with diabetes

mellitus. The study findings emphasize the importance

of effective medication in reducing symptom severity,

improving quality of life, and enhancing psychosocial

functioning in this population. Personalized treatment

approaches, regular monitoring, and adjustments in

medication regimens are crucial for optimizing

outcomes in managing coexisting psychiatric illnesses

in individuals with diabetes.

The results highlight the need for collaborative efforts

between healthcare professionals to address the

complex interplay between diabetes and psychiatric

illnesses. Integrating pharmacological interventions

with psychosocial support can provide a holistic

approach to managing mental health in individuals

with diabetes. Future research should focus on further

understanding the underlying mechanisms and

exploring novel treatment strategies to enhance

medication efficacy and improve psychiatric illness

outcomes in this population.


background image

Volume 03 Issue 07-2023

14


American Journal Of Biomedical Science & Pharmaceutical Innovation
(ISSN

2771-2753)

VOLUME

03

ISSUE

07

P

AGES

:

10-14

SJIF

I

MPACT

FACTOR

(2021:

5.

705

)

(2022:

5.

705

)

(2023:

6.534

)

OCLC

1121105677















































Publisher:

Oscar Publishing Services

Servi

REFERENCES

1.

Balhara Y. Diabetes and psychiatric disorders.

Indian J Endocrinol Metab 2011;15(4):274.

2.

2. Sun N, Lou P, Shang Y, Zhang P, Wang J, Chang

G et al. Prevalence and determinants of

depressive and anxiety symptoms in adults with

type 2 diabetes in China: a cross-sectional study.

BMJ Open 2016;6(8):1-8.

3.

Subramaniam M, Chong S, Pek E. Diabetes

Mellitus and Impaired Glucose Tolerance in

Patients with Schizophrenia. Can J Psychiatry

2003;48(5):345-47.

4.

4. Huang C, Wang S, Lee M, Chiu H. Prevalence

and incidence of mental illness in diabetes: A

national population-based cohort study.

Diabetes Res Clin Practice 2011;93(1):106-14.

5.

5. Agarwal A, Jadhav P, Deshmukh Y. Prescribing

pattern and efficacy of anti -diabetic drugs in

maintaining optimal glycemic levels in diabetic

patients. J Basic Clin Pharm 2014;5(3):79.

6.

6. Fourrier A, Gasquet I, Allicar M, Bouhassira M,

Lépine J, Bégaud B. Patterns of neuroleptic drug

prescription: a national cross - sectional survey

of a random sample of French psychiatrists.

Br J Pharmacol 2001;49(1):80-86.

7.

7. Surwit R, Schneider M, Feinglos M.Stress and

Diabetes Mellitus. Diabetes Care 1992;15(10):1413-

22.

8.

8. Elamoshy R, Bird Y, Thorpe L, Moraros J.

Risk of Depression and Suicidality among

Diabetic Patients: A Systematic Review and

Meta - Analysis. J Clin Med 2018;7(11):445.

9.

9. Khandelwal D, Bahety P, Agarwal G, Dutta

D, Kalra S, Taparia P et al. Occurrence and

predictors of depression and poor quality of life

among patients with Type -2 diabetes: A

Northern India perspective. Indian J Endocrinol

Metab 2017;21(4):564.

10.

10. AlBekairy A, AbuRuz S, Alsabani B, Alshehri

A, Aldebasi T, Alkatheri A et al. Exploring Factors

Associated with Depression and Anxiety

among Hospitalized Patients with Type 2

Diabetes Mellitus. Medical Principles and

Practice 2017;26(6):547-53.

References

Balhara Y. Diabetes and psychiatric disorders. Indian J Endocrinol Metab 2011;15(4):274.

Sun N, Lou P, Shang Y, Zhang P, Wang J, Chang G et al. Prevalence and determinants of depressive and anxiety symptoms in adults with type 2 diabetes in China: a cross-sectional study. BMJ Open 2016;6(8):1-8.

Subramaniam M, Chong S, Pek E. Diabetes Mellitus and Impaired Glucose Tolerance in Patients with Schizophrenia. Can J Psychiatry 2003;48(5):345-47.

Huang C, Wang S, Lee M, Chiu H. Prevalence and incidence of mental illness in diabetes: A national population-based cohort study. Diabetes Res Clin Practice 2011;93(1):106-14.

Agarwal A, Jadhav P, Deshmukh Y. Prescribing pattern and efficacy of anti -diabetic drugs in maintaining optimal glycemic levels in diabetic patients. J Basic Clin Pharm 2014;5(3):79.

Fourrier A, Gasquet I, Allicar M, Bouhassira M, Lépine J, Bégaud B. Patterns of neuroleptic drug prescription: a national cross - sectional survey of a random sample of French psychiatrists. Br J Pharmacol 2001;49(1):80-86.

Surwit R, Schneider M, Feinglos M.Stress and Diabetes Mellitus. Diabetes Care 1992;15(10):1413-22.

Elamoshy R, Bird Y, Thorpe L, Moraros J. Risk of Depression and Suicidality among Diabetic Patients: A Systematic Review and Meta - Analysis. J Clin Med 2018;7(11):445.

Khandelwal D, Bahety P, Agarwal G, Dutta D, Kalra S, Taparia P et al. Occurrence and predictors of depression and poor quality of life among patients with Type -2 diabetes: A Northern India perspective. Indian J Endocrinol Metab 2017;21(4):564.

AlBekairy A, AbuRuz S, Alsabani B, Alshehri A, Aldebasi T, Alkatheri A et al. Exploring Factors Associated with Depression and Anxiety among Hospitalized Patients with Type 2 Diabetes Mellitus. Medical Principles and Practice 2017;26(6):547-53.