Risk factors and prognosis of the development of pseudophakic myopia in children

Lola Khamrayeva, D.Y. Narzullaeva

Recent studies indicate the prevalence of myopic refraction in children with pseudophakia, which significantly reduces the func­tional results of treatment and may be an indication for replacing the intraocular lens (IOL). Therefore, studies conducted to achieve the target refraction in children with pseudophakia are relevant.

Purpose — to determine the risk factors for the prognosis of myopic refraction in children after extraction of congenital cataract and IOL implantation.

Material and methods. The study presents the results of refraction examination in 69 (110 eyes) children aged 1 to 12 years 36 months after extraction of congenital cataract with implantation of soft IOL.

Results. The obtained data of anamnesis, results of ophthalmological, echobiometric, clinical and laboratory studies were sub­jected to statistical processing assessing the significance of differences in outcomes depending on the impact of possible risk fac­tors for the development of pseudophakic myopia; a regression logistic model and a ROC-curve were constructed.

Conclusion. According to the authors, reliable risk factors for the development of pseudophakic myopia in children can be such in­dicators as axial eye length at the time of IOL implantation exceeding the age norm by more than 0.2 mm; the child from the first pregnancy; the AL/CR ratio of 23.0; myopia on the paired eye; strabismus of more than 4 prism diopters; hereditary load; tension of eye's fibrous capsule: pressure of SI 80 mm Hg at the time of IOL implantation. The presented reliable factors, as well as a combi­nation of less significant signs (the child being outside for less than 1 hour per day, intermarriage of the patients parents, near-sight visual loads ot more than 3 hours per day, the blood Ca level of less than 1.8 mmol/L) can be used for prognosis of the development of pseudophakic myopia and to help make adjustments in the management tactics for patients to achieve target refraction.

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